(Q38299882)

1 September 2017

title

Differential molecular assemblies underlie the dual function of Axin in modulating the WNT and JNK pathways (English)

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1 September 2017

Zhang Y

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1 September 2017

Qiu WJ

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1 September 2017

Liu DX

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1 September 2017

Neo SY

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1 September 2017

He X

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1 September 2017

Lin SC

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1 September 2017

language of work or name

English

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publication date

14 June 2001

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Journal of Biological Chemistry

1 September 2017

published in

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1 September 2017

volume

276

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1 September 2017

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1 September 2017

page(s)

32152-32159

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Wnt signaling: a common theme in animal development

1 September 2017

cites work

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beta-Trcp couples beta-catenin phosphorylation-degradation and regulates Xenopus axis formation

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A member of the Frizzled protein family mediating axis induction by Wnt-5A

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The dishevelled protein is modified by wingless signaling in Drosophila

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XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos

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Functional interaction of beta-catenin with the transcription factor LEF-1

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Identification of c-MYC as a target of the APC pathway

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Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

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The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway

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Essential role for protein kinase B (PKB) in insulin-induced glycogen synthase kinase 3 inactivation. Characterization of dominant-negative mutant of PKB.

21 January 2018

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Phosphorylation and inactivation of glycogen synthase kinase 3 by protein kinase A

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Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos

21 January 2018

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Role of glycogen synthase kinase 3 beta as a negative regulator of dorsoventral axis formation in Xenopus embryos.

21 January 2018

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The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3

21 January 2018

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Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin

21 January 2018

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Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly

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Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

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Stabilization of beta-catenin by genetic defects in melanoma cell lines

21 January 2018

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21 January 2018

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21 January 2018

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Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex

21 January 2018

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The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation

21 January 2018

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Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta

21 January 2018

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Casein kinase iepsilon in the wnt pathway: regulation of beta-catenin function

21 January 2018

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Identification of a domain of Axin that binds to the serine/threonine protein phosphatase 2A and a self-binding domain

21 January 2018

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Axin and hepatocellular carcinomas.

21 January 2018

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AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1

21 January 2018

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Association of the APC gene product with beta-catenin

21 January 2018

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Association of the APC tumor suppressor protein with catenins

21 January 2018

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Regulation of beta-catenin signaling by the B56 subunit of protein phosphatase 2A

21 January 2018

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The APC tumour suppressor has a nuclear export function.

21 January 2018

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Down-regulation of beta-catenin by the colorectal tumor suppressor APC requires association with Axin and beta-catenin.

21 January 2018

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Casein kinase I transduces Wnt signals

21 January 2018

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Axin forms a complex with MEKK1 and activates c-Jun NH(2)-terminal kinase/stress-activated protein kinase through domains distinct from Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104451200

Dimerization choices control the ability of axin and dishevelled to activate c-Jun N-terminal kinase/stress-activated protein kinase

21 January 2018

1 reference

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De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin

21 January 2018

1 reference

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21 January 2018

APC: the plot thickens

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Differential regulation of glycogen synthase kinase 3beta by insulin and Wnt signaling

21 January 2018

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Diverse functions of JNK signaling and c-Jun in stress response and apoptosis

21 January 2018

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Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

21 January 2018

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Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation

21 January 2018

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The adenomatous polyposis coli tumor suppressor protein localizes to plasma membrane sites involved in active cell migration.

21 January 2018

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Deletion of an amino-terminal sequence beta-catenin in vivo and promotes hyperphosporylation of the adenomatous polyposis coli tumor suppressor protein

21 January 2018

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NH2-terminal deletion of beta-catenin results in stable colocalization of mutant beta-catenin with adenomatous polyposis coli protein and altered MDCK cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104451200

Apical membrane localization of the adenomatous polyposis coli tumor suppressor protein and subcellular distribution of the beta-catenin destruction complex in polarized epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104451200

Domains of axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104451200

MEK kinase 1 (MEKK1) transduces c-Jun NH2-terminal kinase activation in response to changes in the microtubule cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104451200

21 January 2018

Identifiers

DOI

10.1074/JBC.M104451200

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1 September 2017

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