(Q40915793)

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Axin forms a complex with MEKK1 and activates c-Jun NH(2)-terminal kinase/stress-activated protein kinase through domains distinct from Wnt signaling

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Europe PubMed Central

PubMed publication ID

24 September 2017

Axin forms a complex with MEKK1 and activates c-Jun NH(2)-terminal kinase/stress-activated protein kinase through domains distinct from Wnt signaling (English)

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

author name string

Zhang Y

1

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

Neo SY

2

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

Wang X

3

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

Han J

4

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Europe PubMed Central

PubMed publication ID

24 September 2017

Lin SC

5

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Europe PubMed Central

PubMed publication ID

24 September 2017

language of work or name

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publication date

1 December 1999

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Europe PubMed Central

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24 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

24 September 2017

274

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Europe PubMed Central

PubMed publication ID

24 September 2017

49

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

35247-35254

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation

1 reference

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Wnt signaling: a common theme in animal development

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Wnt signaling: why is everything so negative?

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Mechanisms of Wnt signaling in development

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Basic processes underlying Agrobacterium-mediated DNA transfer to plant cells

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Lessons learned, promises kept: a biologist's eye view of the Genome Project

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Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta

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21 January 2018

Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin

1 reference

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21 January 2018

Axis determination in Xenopus involves biochemical interactions of axin, glycogen synthase kinase 3 and beta-catenin.

1 reference

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Axin, a negative regulator of the wnt signaling pathway, directly interacts with adenomatous polyposis coli and regulates the stabilization of beta-catenin

1 reference

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Bridging of beta-catenin and glycogen synthase kinase-3beta by axin and inhibition of beta-catenin-mediated transcription

1 reference

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Axin prevents Wnt-3a-induced accumulation of beta-catenin

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XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos

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Functional interaction of beta-catenin with the transcription factor LEF-1

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Identification of c-MYC as a target of the APC pathway

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RGS proteins and signaling by heterotrimeric G proteins

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Mammalian RGS proteins: barbarians at the gate

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Mitogen-activated protein kinase cascades and regulation of gene expression

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Mitogen-activated protein kinase pathways

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Organization and regulation of mitogen-activated protein kinase signaling pathways

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Mitogen-activated protein kinases: specific messages from ubiquitous messengers

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Platelet-activating factor induces NF-kappa B activation through a G protein-coupled pathway

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21 January 2018

Characterization of the structure and function of a novel MAP kinase kinase (MKK6)

1 reference

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21 January 2018

Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH2-terminal kinase

1 reference

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21 January 2018

Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

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Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

1 reference

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Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways

1 reference

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Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx

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Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction

1 reference

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21 January 2018

Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms

1 reference

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14-3-3 proteins interact with specific MEK kinases

1 reference

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Grb2 interaction with MEK-kinase 1 is involved in regulation of Jun-kinase activities in response to epidermal growth factor

1 reference

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JNKK1 organizes a MAP kinase module through specific and sequential interactions with upstream and downstream components mediated by its amino-terminal extension

1 reference

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21 January 2018

Identification of a domain of Axin that binds to the serine/threonine protein phosphatase 2A and a self-binding domain

1 reference

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21 January 2018

Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta

1 reference

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21 January 2018

Axil, a member of the Axin family, interacts with both glycogen synthase kinase 3beta and beta-catenin and inhibits axis formation of Xenopus embryos

1 reference

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21 January 2018

Phosphorylation of axin, a Wnt signal negative regulator, by glycogen synthase kinase-3beta regulates its stability

1 reference

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21 January 2018

Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex

1 reference

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Functional domains of axin. Importance of the C terminus as an oligomerization domain

1 reference

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Domains of axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization

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Phosphorylation of the MAP kinase ERK2 promotes its homodimerization and nuclear translocation

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Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling

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Dishevelled proteins lead to two signaling pathways. Regulation of LEF-1 and c-Jun N-terminal kinase in mammalian cells

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The dishevelled protein is modified by wingless signaling in Drosophila

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The role of RhoA in tissue polarity and Frizzled signalling

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DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta-catenin stability

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Integration of MAP kinase signal transduction pathways at the serum response element

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Distortion of proximodistal information causes JNK-dependent apoptosis in Drosophila wing

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Identifiers

10.1074/JBC.274.49.35247

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

ResearchGate publication ID

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