(Q38079791)

28 August 2017

title

Parkinson's disease and alpha synuclein: is Parkinson's disease a prion-like disorder? (English)

1 reference

28 August 2017

0 references

1 reference

1 reference

Patrik Brundin

1 reference

28 August 2017

Charles Warren Olanow

series ordinal

object named as

C Warren Olanow

1 reference

28 August 2017

language of work or name

English

0 references

publication date

1 January 2013

1 reference

28 August 2017

1 reference

28 August 2017

1 reference

28 August 2017

1 reference

28 August 2017

page(s)

31-40

1 reference

Cell biology. A unifying role for prions in neurodegenerative diseases

28 August 2017

cites work

1 reference

Shattuck lecture--neurodegenerative diseases and prions

21 January 2018

1 reference

21 January 2018

1 reference

Lewy-body formation is an aggresome-related process: a hypothesis

21 January 2018

1 reference

Lewy pathology is not the first sign of degeneration in vulnerable neurons in Parkinson disease

21 January 2018

1 reference

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

21 January 2018

1 reference

α-Synuclein in Lewy bodies

21 January 2018

1 reference

Alpha-synuclein locus duplication as a cause of familial Parkinson's disease

21 January 2018

1 reference

alpha-Synuclein locus triplication causes Parkinson's disease

21 January 2018

1 reference

Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease

21 January 2018

1 reference

Genome-wide association study reveals genetic risk underlying Parkinson's disease

21 January 2018

1 reference

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

21 January 2018

1 reference

Modeling CNS neurodegeneration by overexpression of disease-causing proteins using viral vectors

21 January 2018

1 reference

Neuropathology of sporadic Parkinson's disease: evaluation and changes of concepts

21 January 2018

1 reference

Staging of brain pathology related to sporadic Parkinson's disease

21 January 2018

1 reference

A critical evaluation of the Braak staging scheme for Parkinson's disease.

21 January 2018

1 reference

A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease

21 January 2018

1 reference

Evidence for long-term survival and function of dopaminergic grafts in progressive Parkinson's disease

21 January 2018

1 reference

Neuropathological evidence of graft survival and striatal reinnervation after the transplantation of fetal mesencephalic tissue in a patient with Parkinson's disease

21 January 2018

1 reference

Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease

21 January 2018

1 reference

Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation

21 January 2018

1 reference

Is Parkinson's disease a prion disorder?

21 January 2018

1 reference

Are synucleinopathies prion-like disorders?

21 January 2018

1 reference

Research in motion: the enigma of Parkinson's disease pathology spread

21 January 2018

1 reference

Intravesicular localization and exocytosis of alpha-synuclein and its aggregates.

21 January 2018

1 reference

Assembly-dependent endocytosis and clearance of extracellular alpha-synuclein.

21 January 2018

1 reference

Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein

21 January 2018

1 reference

α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells

21 January 2018

1 reference

Transfer of host-derived α synuclein to grafted dopaminergic neurons in rat

21 January 2018

1 reference

Exogenous alpha-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells

21 January 2018

1 reference

Exogenous α-synuclein fibrils induce Lewy body pathology leading to synaptic dysfunction and neuron death

21 January 2018

1 reference

Neuron-to-neuron transmission of α-synuclein fibrils through axonal transport

21 January 2018

1 reference

Prion-like acceleration of a synucleinopathy in a transgenic mouse model

21 January 2018

1 reference

Pathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice

21 January 2018

1 reference

Alpha-synuclein cell-to-cell transfer and seeding in grafted dopaminergic neurons in vivo

21 January 2018

1 reference

Cell-produced alpha-synuclein is secreted in a calcium-dependent manner by exosomes and impacts neuronal survival

21 January 2018

1 reference

Exosomal cell-to-cell transmission of alpha synuclein oligomers.

21 January 2018

1 reference

Lysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission.

21 January 2018

1 reference

Direct observation of the interconversion of normal and toxic forms of α-synuclein

21 January 2018

1 reference

α-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation

21 January 2018

1 reference

Alpha-synuclein: normal function and role in neurodegenerative diseases.

21 January 2018

1 reference

Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions

21 January 2018

1 reference

Clearance of alpha-synuclein oligomeric intermediates via the lysosomal degradation pathway.

21 January 2018

1 reference

Wild type alpha-synuclein is degraded by chaperone-mediated autophagy and macroautophagy in neuronal cells

21 January 2018

1 reference

Endoproteolytic activity of the proteasome

21 January 2018

1 reference

A precipitating role for truncated alpha-synuclein and the proteasome in alpha-synuclein aggregation: implications for pathogenesis of Parkinson disease

21 January 2018

1 reference

Chaperone-mediated autophagy markers in Parkinson disease brains

21 January 2018

1 reference

Failure of the ubiquitin-proteasome system in Parkinson's disease

21 January 2018

1 reference

Impairment of the ubiquitin-proteasome system causes dopaminergic cell death and inclusion body formation in ventral mesencephalic cultures

21 January 2018

1 reference

Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis

21 January 2018

1 reference

Aggregated and monomeric alpha-synuclein bind to the S6' proteasomal protein and inhibit proteasomal function

21 January 2018

1 reference

Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy

21 January 2018

1 reference

Parkinson's disease, proteins, and prions: milestones

21 January 2018

1 reference

Alterations in lysosomal and proteasomal markers in Parkinson's disease: relationship to alpha-synuclein inclusions

21 January 2018

1 reference

Frequency of bowel movements and the future risk of Parkinson's disease

21 January 2018

1 reference

Progression of Parkinson's disease pathology is reproduced by intragastric administration of rotenone in mice

21 January 2018

1 reference

Environmental toxins trigger PD-like progression via increased alpha-synuclein release from enteric neurons in mice

21 January 2018

1 reference

Transmission of Synucleinopathies in the Enteric Nervous System of A53T Alpha-Synuclein Transgenic Mice

21 January 2018

1 reference

α-Synuclein and protein degradation systems: a reciprocal relationship

21 January 2018

1 reference

Age-associated increases of alpha-synuclein in monkeys and humans are associated with nigrostriatal dopamine depletion: Is this the target for Parkinson's disease?

21 January 2018

1 reference

Characterization of semisynthetic and naturally Nα-acetylated α-synuclein in vitro and in intact cells: implications for aggregation and cellular properties of α-synuclein

21 January 2018

1 reference

Effects of alpha-synuclein immunization in a mouse model of Parkinson's disease

21 January 2018

1 reference

Antibody-aided clearance of extracellular α-synuclein prevents cell-to-cell aggregate transmission

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/MDS.25373

1 reference

release_lkthhjkp75eapilmiqog552jdy

28 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/lkthhjkp75eapilmiqog552jdy

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference