(Q37986997)

26 August 2017

title

Neuroprotective mechanisms of hypothermia in brain ischaemia (English)

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26 August 2017

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Midori A Yenari

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26 August 2017

Hyung Soo Han

series ordinal

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26 August 2017

language of work or name

English

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publication date

22 February 2012

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Nature Reviews Neuroscience

26 August 2017

published in

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26 August 2017

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26 August 2017

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26 August 2017

page(s)

267-278

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Small differences in intraischemic brain temperature critically determine the extent of ischemic neuronal injury

26 August 2017

cites work

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Metabolic downregulation: a key to successful neuroprotection?

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31 March 2020

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31 March 2020

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31 March 2020

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General versus specific actions of mild-moderate hypothermia in attenuating cerebral ischemic damage

31 March 2020

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The changing landscape of ischaemic brain injury mechanisms.

31 March 2020

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Hypothermia rescues hippocampal CA1 neurons and attenuates down-regulation of the AMPA receptor GluR2 subunit after forebrain ischemia

31 March 2020

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Intraischemic but not postischemic brain hypothermia protects chronically following global forebrain ischemia in rats

31 March 2020

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Biphasic Expression of the Fos and Jun Families of Transcription Factors Following Transient Forebrain Ischaemia in the Rat. Effect of Hypothermia

31 March 2020

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Hypothermia enhances heat-shock protein 70 production in ischemic brains

31 March 2020

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Characterization of hypothermia-induced cellular stress response in mouse tissues

31 March 2020

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Antiapoptotic and anti-inflammatory mechanisms of heat-shock protein protection

31 March 2020

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The effect of hypothermia on induction of heat shock protein (HSP)-72 in ischemic brain

31 March 2020

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Mild hypothermia reduces apoptosis of mouse neurons in vitro early in the cascade.

31 March 2020

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The MicroRNAs and Stroke: No Need to be Coded to be Counted

31 March 2020

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Therapeutic hypothermia alters microRNA responses to traumatic brain injury in rats

31 March 2020

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Mitochondria and apoptosis

31 March 2020

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Death receptors: signaling and modulation

31 March 2020

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Therapeutic hypothermia: neuroprotective mechanisms

31 March 2020

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Protein kinase C delta mediates cerebral reperfusion injury in vivo.

31 March 2020

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Protein kinase C delta cleavage initiates an aberrant signal transduction pathway after cardiac arrest and oxygen glucose deprivation

31 March 2020

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The protective effect of early hypothermia on PTEN phosphorylation correlates with free radical inhibition in rat stroke

31 March 2020

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Epsilon PKC may contribute to the protective effect of hypothermia in a rat focal cerebral ischemia model

31 March 2020

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Fas (CD95/APO-1) plays a role in the pathophysiology of focal cerebral ischemia

31 March 2020

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FasL shedding is reduced by hypothermia in experimental stroke

31 March 2020

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Multiple roles for MMPs and TIMPs in cerebral ischemia

31 March 2020

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The metalloproteinase matrilysin proteolytically generates active soluble Fas ligand and potentiates epithelial cell apoptosis

31 March 2020

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Mild to moderate hypothermia prevents microvascular basal lamina antigen loss in experimental focal cerebral ischemia

31 March 2020

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Reduction in levels of matrix metalloproteinases and increased expression of tissue inhibitor of metalloproteinase-2 in response to mild hypothermia therapy in experimental stroke.

31 March 2020

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Influence of therapeutic hypothermia on matrix metalloproteinase activity after traumatic brain injury in rats

31 March 2020

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Topographically graded postischemic presence of metalloproteinases is inhibited by hypothermia

31 March 2020

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Mild hypothermia attenuates cytochrome c release but does not alter Bcl-2 expression or caspase activation after experimental stroke

31 March 2020

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Molecular characterization of mitochondrial apoptosis-inducing factor

31 March 2020

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Conditions of protection by hypothermia and effects on apoptotic pathways in a rat model of permanent middle cerebral artery occlusion

31 March 2020

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PTEN deletion prevents ischemic brain injury by activating the mTOR signaling pathway

31 March 2020

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Delayed hypothermia preferentially increases expression of brain-derived neurotrophic factor exon III in rat hippocampus after asphyxial cardiac arrest

31 March 2020

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Hypothermic reperfusion after cardiac arrest augments brain-derived neurotrophic factor activation

31 March 2020

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Regional changes in glial cell line-derived neurotrophic factor after cardiac arrest and hypothermia in rats

31 March 2020

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The effect of hypothermia on the expression of neurotrophin mRNA in the hippocampus following transient cerebral ischemia in the rat.

31 March 2020

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Hypothermia differentially increases extracellular signal-regulated kinase and stress-activated protein kinase/c-Jun terminal kinase activation in the hippocampus during reperfusion after asphyxial cardiac arrest

31 March 2020

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Hypothermia and ERK activation after cardiac arrest

31 March 2020

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Hypothermia enhances bcl-2 expression and protects against oxidative stress-induced cell death in Chinese hamster ovary cells

31 March 2020

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Mild hypothermia increases Bcl-2 protein expression following global cerebral ischemia

31 March 2020

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Akt contributes to neuroprotection by hypothermia against cerebral ischemia in rats.

31 March 2020

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The inflammatory response in stroke

31 March 2020

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The dual role of the neuroinflammatory response after ischemic stroke: modulatory effects of hypothermia

31 March 2020

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Whole Body Hypothermia and Oxidative Stress in Babies With Hypoxic-Ischemic Brain Injury

31 March 2020

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Influence of mild hypothermia on inducible nitric oxide synthase expression and reactive nitrogen production in experimental stroke and inflammation.

31 March 2020

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Mild hypothermia inhibits inflammation after experimental stroke and brain inflammation

31 March 2020

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Mild hypothermia alone or in combination with anesthetic post-conditioning reduces expression of inflammatory cytokines in the cerebral cortex of pigs after cardiopulmonary resuscitation

31 March 2020

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Macrophage inflammatory protein-3alpha plays a key role in the inflammatory cascade in rat focal cerebral ischemia

31 March 2020

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IL-10 production is reduced by hypothermia but augmented by hyperthermia in rat microglia

31 March 2020

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The effect of therapeutic hypothermia on the expression of inflammatory response genes following moderate traumatic brain injury in the rat

31 March 2020

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Influence of hypothermia on post-ischemic inflammation: role of nuclear factor kappa B (NFkappaB)

31 March 2020

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Mild hypothermia inhibits nuclear factor-kappaB translocation in experimental stroke.

31 March 2020

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Inflammation and NFkappaB activation is decreased by hypothermia following global cerebral ischemia.

31 March 2020

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Roles of nuclear factor kappaB in neuronal survival and plasticity

31 March 2020

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Hypothermia suppresses inflammation via ERK signaling pathway in stimulated microglial cells

31 March 2020

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The importance of brain temperature in alterations of the blood-brain barrier following cerebral ischemia.

31 March 2020

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Effect of delayed mild brain hypothermia on edema formation after intracerebral hemorrhage in rats.

31 March 2020

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The influence of hypothermia on outcome after intracerebral hemorrhage in rats.

31 March 2020

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Combinational Therapy Using Hypothermia and the Immunophilin Ligand FK506 to Target Altered Pial Arteriolar Reactivity, Axonal Damage, and Blood–Brain Barrier Dysfunction after Traumatic Brain Injury in Rat

31 March 2020

1 reference

A two-hour window for hypothermic modulation of early events that impact delayed opening of the rat blood-brain barrier after ischemia

31 March 2020

1 reference

Minocycline and hypothermia for reperfusion injury after focal cerebral ischemia in the rat: effects on BBB breakdown and MMP expression in the acute and subacute phase

31 March 2020

1 reference

Post-ischemic hypothermia attenuates loss of the vascular basement membrane proteins, agrin and SPARC, and the blood-brain barrier disruption after global cerebral ischemia

31 March 2020

1 reference

The effect of moderate hypothermia in acute ischemic stroke on pericyte migration: an ultrastructural study

31 March 2020

1 reference

Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke.

31 March 2020

1 reference

Cerebral cortical aquaporin-4 expression in brain edema following cardiac arrest in rats

31 March 2020

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Effect of therapeutic moderate hypothermia on multi-drug resistance protein 1-mediated transepithelial transport of drugs

31 March 2020

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Treatment of intracerebral hemorrhage in rats with 12 h, 3 days and 6 days of selective brain hypothermia

31 March 2020

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Hypothermia reduces perihemorrhagic edema after intracerebral hemorrhage

31 March 2020

1 reference

Coagulopathy by hypothermia and acidosis: mechanisms of thrombin generation and fibrinogen availability

31 March 2020

1 reference

The effects of hypothermia on fibrinogen metabolism and coagulation function in swine

31 March 2020

1 reference

Forebrain neurogenesis after focal Ischemic and traumatic brain injury

31 March 2020

1 reference

Angiogenesis, Neurogenesis and Neuroplasticity in Ischemic Stroke

31 March 2020

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Neurogenesis in the aged and neurodegenerative brain

31 March 2020

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Decline in adult neurogenesis during aging follows a topographic pattern in the mouse hippocampus

31 March 2020

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A decrease of cell proliferation by hypothermia in the hippocampus of the neonatal rat.

31 March 2020

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Post-ischemic hypothermia promotes generation of neural cells and reduces apoptosis by Bcl-2 in the striatum of neonatal rat brain

31 March 2020

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Moderate low temperature preserves the stemness of neural stem cells and suppresses apoptosis of the cells via activation of the cold-inducible RNA binding protein

31 March 2020

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Therapeutic hypothermia influences cell genesis and survival in the rat hippocampus following global ischemia.

31 March 2020

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Mild hypothermia has no long-term impact on postischemic neurogenesis in rats

31 March 2020

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Oligodendrocyte vulnerability following traumatic brain injury in rats

31 March 2020

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OLIGODENDROCYTE VULNERABILITY FOLLOWING TRAUMATIC BRAIN INJURY IN RATS: EFFECT OF MODERATE HYPOTHERMIA.

31 March 2020

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Hypothermia-induced increase of oligodendrocyte precursor cells: Possible involvement of plasmalemmal voltage-dependent anion channel 1

31 March 2020

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The effect of cerebral hypothermia on white and grey matter injury induced by severe hypoxia in preterm fetal sheep

31 March 2020

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Stem cells in stroke repair: current success and future prospects

31 March 2020

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Focal cerebral ischemia induces a multilineage cytogenic response from adult subventricular zone that is predominantly gliogenic

31 March 2020

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The Unusual Response of Serotonergic Neurons after CNS Injury: Lack of Axonal Dieback and Enhanced Sprouting within the Inhibitory Environment of the Glial Scar

31 March 2020

1 reference

Neuroprotective role of astrocytes in cerebral ischemia: focus on ischemic preconditioning

31 March 2020

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Effect of mild hypothermia on angiogenesis in rats with focal cerebral ischemia

31 March 2020

1 reference

Body Cooling Ameliorating Spinal Cord Injury May Be Neurogenesis-, Anti-inflammation- and Angiogenesis-Associated in Rats

31 March 2020

1 reference

Brain Cooling-Stimulated Angiogenesis and Neurogenesis Attenuated Traumatic Brain Injury in Rats

31 March 2020

1 reference

A large screening of angiogenesis biomarkers and their association with neurological outcome after ischemic stroke

31 March 2020

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Neuroprotection of ischemic brain by vascular endothelial growth factor is critically dependent on proper dosage and may be compromised by angiogenesis

31 March 2020

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Hypothermia-induced neurite outgrowth is mediated by tumor necrosis factor-alpha

31 March 2020

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S100B modulates IL-6 release and cytotoxicity from hypothermic brain cells and inhibits hypothermia-induced axonal outgrowth

31 March 2020

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Effect of therapeutic mild hypothermia on the genomics of the hippocampus after moderate traumatic brain injury in rats

31 March 2020

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Complications and treatment of mild hypothermia

31 March 2020

1 reference

Hibernation in Ground Squirrels Induces State and Species-Specific Tolerance to Hypoxia and Aglycemia: An In Vitro Study in Hippocampal Slices

31 March 2020

1 reference

Protein kinase C epsilon activation delays neuronal depolarization during cardiac arrest in the euthermic arctic ground squirrel

31 March 2020

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Hypoxia tolerance in mammalian heterotherms.

31 March 2020

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Hibernation in black bears: independence of metabolic suppression from body temperature.

31 March 2020

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Cold-inducible RNA binding protein (CIRP) expression is modulated by alternative mRNAs

31 March 2020

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Effects of hypothermia and cerebral ischemia on cold-inducible RNA-binding protein mRNA expression in rat brain

31 March 2020

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Cirp protects against tumor necrosis factor-alpha-induced apoptosis via activation of extracellular signal-regulated kinase

31 March 2020

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Hypothermia causes a reversible, p53-mediated cell cycle arrest in cultured fibroblasts

31 March 2020

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12 December 2020

CD95 ligand (Fas-L/APO-1L) and tumor necrosis factor-related apoptosis-inducing ligand mediate ischemia-induced apoptosis in neurons

1 reference

12 December 2020

Effect of local mild hypothermia on expression of aquaporin-4 following intracerebral hemorrhage in rats

1 reference

12 December 2020

Mild Hypothermia Attenuates Intercellular Adhesion Molecule-1 Induction via Activation of Extracellular Signal-Regulated Kinase-1/2 in a Focal Cerebral Ischemia Model

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12 December 2020

Therapeutic modulation of brain temperature: relevance to ischemic brain injury

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12 December 2020

Identifiers

DOI

10.1038/NRN3174

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26 August 2017

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