(Q41911841)

English

Combinational Therapy Using Hypothermia and the Immunophilin Ligand FK506 to Target Altered Pial Arteriolar Reactivity, Axonal Damage, and Blood–Brain Barrier Dysfunction after Traumatic Brain Injury in Rat

scientific article published on December 15, 2010

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Combinational Therapy Using Hypothermia and the Immunophilin Ligand FK506 to Target Altered Pial Arteriolar Reactivity, Axonal Damage, and Blood–Brain Barrier Dysfunction after Traumatic Brain Injury in Rat (English)

reason for preferred rank

most precise value

1 reference

10.1038/JCBFM.2010.208

https://api.crossref.org/works/10.1038/JCBFM.2010.208

20 November 2024

Combinational therapy using hypothermia and the immunophilin ligand FK506 to target altered pial arteriolar reactivity, axonal damage, and blood-brain barrier dysfunction after traumatic brain injury in rat (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21157473

20 November 2024

traumatic brain injury

0 references

blood–brain barrier

1 reference

based on heuristic

inferred from title

author name string

Yasutaka Oda

1

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Guoyi Gao

2

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Enoch P. Wei

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21157473

20 November 2024

John T. Povlishock

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21157473

20 November 2024

language of work or name

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21157473

20 November 2024

publication date

15 December 2010

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

full work available at URL

https://journals.sagepub.com/doi/pdf/10.1038/jcbfm.2010.208

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21157473

20 November 2024

https://europepmc.org/articles/PMC3070975

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21157473

20 November 2024

https://europepmc.org/articles/PMC3070975?pdf=render

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21157473

20 November 2024

https://doi.org/10.1038/jcbfm.2010.208

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21157473

20 November 2024

https://journals.sagepub.com/doi/pdf/10.1038/jcbfm.2010.208

1 reference

10.1038/JCBFM.2010.208

https://api.crossref.org/works/10.1038/JCBFM.2010.208

20 November 2024

https://journals.sagepub.com/doi/full-xml/10.1038/jcbfm.2010.208

1 reference

10.1038/JCBFM.2010.208

https://api.crossref.org/works/10.1038/JCBFM.2010.208

20 November 2024

Journal of Cerebral Blood Flow & Metabolism

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

31

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

4

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

1143-1154

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

The adverse pial arteriolar and axonal consequences of traumatic brain injury complicated by hypoxia and their therapeutic modulation with hypothermia in rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070975

5 June 2018

Posthypothermic rewarming considerations following traumatic brain injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070975

5 June 2018

Clinical study of mild hypothermia treatment for severe traumatic brain injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070975

5 June 2018

Protection in animal models of brain and spinal cord injury with mild to moderate hypothermia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070975

5 June 2018

The long-term microvascular and behavioral consequences of experimental traumatic brain injury after hypothermic intervention

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070975

5 June 2018

Therapeutic hypothermia preserves antioxidant defenses after severe traumatic brain injury in infants and children

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070975

5 June 2018

Hypothermia treatment for traumatic brain injury: a systematic review and meta-analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070975

5 June 2018

Effects of hypothermia on drug disposition, metabolism, and response: A focus of hypothermia-mediated alterations on the cytochrome P450 enzyme system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070975

5 June 2018

Evaluation of pharmacological treatment strategies in traumatic brain injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070975

5 June 2018

Update of neuropathology and neurological recovery after traumatic brain injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070975

5 June 2018

Effect of intravenous corticosteroids on death within 14 days in 10008 adults with clinically significant head injury (MRC CRASH trial): randomised placebo-controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070975

5 June 2018

Mild hypothermia enhances the neuroprotective effects of FK506 and expands its therapeutic window following transient focal ischemia in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070975

5 June 2018

FK506 abrogates delayed neuronal death via suppression of nitric oxide production in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070975

5 June 2018

Clinical trials in head injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070975

5 June 2018

The visualization of a new class of traumatically injured axons through the use of a modified method of microwave antigen retrieval

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070975

5 June 2018

Immunosuppressant FK506 enhances phosphorylation of nitric oxide synthase and protects against glutamate neurotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070975

5 June 2018

Glutamate release and free radical production following brain injury: effects of posttraumatic hypothermia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070975

5 June 2018

In vivo bioassay of endothelium-derived relaxing factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070975

5 June 2018

Differential central nervous system responses following single and multiple recombinant interleukin-2 infusions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070975

5 June 2018

Traumatically induced axonal injury: pathogenesis and pathobiological implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070975

5 June 2018

Cerebral vascular responsiveness after experimental traumatic brain injury: the beneficial effects of delayed hypothermia combined with superoxide dismutase administration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070975

18 August 2018

Tacrolimus depresses local immune cell infiltration but fails to reduce cortical contusion volume in brain-injured rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070975

18 August 2018

Administration of the immunophilin ligand FK506 differentially attenuates neurofilament compaction and impaired axonal transport in injured axons following diffuse traumatic brain injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070975

18 August 2018

Superoxide targets calcineurin signaling in vascular endothelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070975

18 August 2018

FK506 suppresses E-selectin, ICAM-1 and VCAM-1 expression on vascular endothelial cells by inhibiting tumor necrosis factor alpha secretion from peripheral blood mononuclear cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070975

18 August 2018

Effects of delayed, prolonged hypothermia on the pial vascular response after traumatic brain injury in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070975

18 August 2018

Tacrolimus, a Potential Neuroprotective Agent, Ameliorates Ischemic Brain Damage and Neurologic Deficits after Focal Cerebral Ischemia in Nonhuman Primates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070975

18 August 2018

Posttraumatic hypothermia followed by slow rewarming protects the cerebral microcirculation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070975

18 August 2018

The immunophilin ligand FK506 attenuates axonal injury in an impact-acceleration model of traumatic brain injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070975

18 August 2018

Cyclosporin A significantly ameliorates cortical damage following experimental traumatic brain injury in rodents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070975

18 August 2018

Moderate posttraumatic hypothermia decreases early calpain-mediated proteolysis and concomitant cytoskeletal compromise in traumatic axonal injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070975

18 August 2018

Posttraumatic hypothermia in the treatment of axonal damage in an animal model of traumatic axonal injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070975

18 August 2018

Effects of Temperature on Cerebral Tissue Oxygen Tension, Carbon Dioxide Tension, and pH during Transient Global Ischemia in Rabbits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070975

18 August 2018

Hypothermia Therapy after Traumatic Brain Injury in Children

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2010.208

21 January 2018

Effects of hypothermia on intracranial pressure and brain edema formation: studies in a rat acute subdural hematoma model

1 reference

https://pubmed.ncbi.nlm.nih.gov/21157473

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detailed Description of a Cranial Window Technique for Acute and Chronic Experiments

1 reference

https://pubmed.ncbi.nlm.nih.gov/21157473

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition by free radical scavengers and by cyclooxygenase inhibitors of pial arteriolar abnormalities from concussive brain injury in cats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21157473

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

American Journal of Physiology

15

255

H1259

author name string

Kontos HA

publication date

1988

1 reference

10.1038/JCBFM.2010.208

https://api.crossref.org/works/10.1038/JCBFM.2010.208

20 November 2024

Identifiers

10.1038/JCBFM.2010.208

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

ResearchGate publication ID

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