(Q37741070)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20437210%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

review article

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title

Membrane biophysics and mechanics in Alzheimer's disease (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20437210%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

0 references

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20437210%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Xiaoguang Yang

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20437210%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

James C-M Lee

series ordinal

1 reference

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1 February 2020

publication date

1 May 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20437210%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

published in

Molecular Neurobiology

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20437210%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

volume

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20437210%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

issue

2-3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20437210%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

page(s)

138-148

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20437210%20AND%20SRC:MED&resulttype=core&format=json

Microglia in Alzheimer's disease and transgenic models. How close the fit?

1 February 2020

cites work

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https://api.crossref.org/works/10.1007%2FS12035-010-8121-9

Association of microglia with amyloid plaques in brains of APP23 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-010-8121-9

Protein kinase C inhibits the transplasma membrane influx of Ca2+ triggered by 4-aminopyridine in Jurkat T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-010-8121-9

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-010-8121-9

Control of phospholipase A2 activities for the treatment of inflammatory conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-010-8121-9

Vascular smooth muscle actin is reduced in Alzheimer disease brain: a quantitative analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-010-8121-9

Activated Microglial Cells Are Colocalized With Perivascular Deposits of Amyloid-β Protein in Alzheimer’s Disease Brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-010-8121-9

Effect of endothelial cell polarity on beta-amyloid-induced migration of monocytes across normal and AD endothelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-010-8121-9

The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae

21 January 2018

1 reference

12 December 2020

NAD(P)H oxidase-mediated reactive oxygen species production alters astrocyte membrane molecular order via phospholipase A2.

1 reference

12 December 2020

Cytosolic phospholipase A2 (cPLA2) immunoreactivity is elevated in Alzheimer's disease brain

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12 December 2020

The Kinetics of L-selectin Tethers and the Mechanics of Selectin-mediated Rolling

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12 December 2020

Demonstration by FRET of BACE interaction with the amyloid precursor protein at the cell surface and in early endosomes

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12 December 2020

Physiological levels of beta-amyloid induce cerebral vessel dysfunction and reduce endothelial nitric oxide production

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12 December 2020

Secretory phospholipase A2 type III enhances alpha-secretase-dependent amyloid precursor protein processing through alterations in membrane fluidity

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12 December 2020

Phospholipase A2 in astrocytes: responses to oxidative stress, inflammation, and G protein-coupled receptor agonists

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12 December 2020

Exclusively targeting beta-secretase to lipid rafts by GPI-anchor addition up-regulates beta-site processing of the amyloid precursor protein

1 reference

12 December 2020

beta-Amyloid peptide and a 3-kDa fragment are derived by distinct cellular mechanisms.

1 reference

12 December 2020

Amyloid-beta induces Smac release via AP-1/Bim activation in cerebral endothelial cells.

1 reference

12 December 2020

High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation

1 reference

12 December 2020

The origins of Alzheimer disease: a is for amyloid.

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12 December 2020

Differential degeneration of the cerebral microvasculature in Alzheimer's disease.

1 reference

12 December 2020

Secretory PLA2-IIA: a new inflammatory factor for Alzheimer's disease

1 reference

12 December 2020

Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein

1 reference

12 December 2020

The roles of NADPH oxidase and phospholipases A2 in oxidative and inflammatory responses in neurodegenerative diseases

1 reference

12 December 2020

Alzheimer's disease: the amyloid cascade hypothesis

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12 December 2020

Effect of amyloid beta on capacitive calcium entry in neural 2a cells

1 reference

12 December 2020

Fresh and globular amyloid beta protein (1-42) induces rapid cellular degeneration: evidence for AbetaP channel-mediated cellular toxicity

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12 December 2020

SOD1 rescues cerebral endothelial dysfunction in mice overexpressing amyloid precursor protein

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12 December 2020

Decreased phospholipase A2 activity in Alzheimer brains.

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12 December 2020

Arachidonic acid preserves hippocampal neuron membrane fluidity in senescent rats

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12 December 2020

Ultrastructural features of the blood-brain barrier in biopsy tissue from Alzheimer's disease patients.

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12 December 2020

A novel sorting nexin modulates endocytic trafficking and alpha-secretase cleavage of the amyloid precursor protein

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12 December 2020

Increased oxidative damage in nuclear and mitochondrial DNA in Alzheimer's disease

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12 December 2020

The Amyloid β‐Protein of Alzheimer's Disease Increases Acetylcholinesterase Expression by Increasing Intracellular Calcium in Embryonal Carcinoma P19 Cells

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12 December 2020

Metal ions, pH, and cholesterol regulate the interactions of Alzheimer's disease amyloid-beta peptide with membrane lipid

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12 December 2020

Lipid rafts play an important role in A beta biogenesis by regulating the beta-secretase pathway

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12 December 2020

Inhibitors of brain phospholipase A2 activity: their neuropharmacological effects and therapeutic importance for the treatment of neurologic disorders

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12 December 2020

Membrane cholesterol interferes with neuronal apoptosis induced by soluble oligomers but not fibrils of amyloid-beta peptide

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12 December 2020

Apolipoprotein E4 suppresses delayed-rectifier potassium channels in membrane patches excised from hippocampal neurons

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12 December 2020

Brain membrane cholesterol domains, aging and amyloid beta-peptides

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12 December 2020

Chronic LPS exposure produces changes in intrinsic membrane properties and a sustained IL-beta-dependent increase in GABAergic inhibition in hippocampal CA1 pyramidal neurons

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12 December 2020

Reduced membrane lipids in the cortex of Alzheimer's disease transgenic mice

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12 December 2020

Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts

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12 December 2020

Squalestatin protects neurons and reduces the activation of cytoplasmic phospholipase A2 by Abeta(1-42).

1 reference

12 December 2020

Phospholipases A2 mediate amyloid-beta peptide-induced mitochondrial dysfunction.

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12 December 2020

Influence of cholesterol on phospholipid bilayers phase domains as detected by Laurdan fluorescence

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12 December 2020

Differential expression of oxidative phosphorylation genes in patients with Alzheimer's disease: implications for early mitochondrial dysfunction and oxidative damage.

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12 December 2020

Abeta1-42 stimulates actin polymerization in hippocampal neurons through Rac1 and Cdc42 Rho GTPases

1 reference

12 December 2020

Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function

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12 December 2020

Amyloid beta-peptide interactions with neuronal and glial cell plasma membrane: binding sites and implications for Alzheimer's disease

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12 December 2020

Plasma membrane cholesterol controls the cytotoxicity of Alzheimer's disease AbetaP (1-40) and (1-42) peptides.

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12 December 2020

Gene expression profiles of transcripts in amyloid precursor protein transgenic mice: up-regulation of mitochondrial metabolism and apoptotic genes is an early cellular change in Alzheimer's disease.

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12 December 2020

Soluble aggregates of the amyloid-beta protein activate endothelial monolayers for adhesion and subsequent transmigration of monocyte cells

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12 December 2020

Evidence that production and release of amyloid beta-protein involves the endocytic pathway

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12 December 2020

Phospholipase A2, reactive oxygen species, and lipid peroxidation in cerebral ischemia

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12 December 2020

Sorting through the cell biology of Alzheimer's disease: intracellular pathways to pathogenesis

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12 December 2020

Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha -secretase ADAM 10.

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12 December 2020

The reaction-limited kinetics of membrane-to-surface adhesion and detachment

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12 December 2020

beta-amyloid-induced migration of monocytes across human brain endothelial cells involves RAGE and PECAM-1.

1 reference

12 December 2020

BACE1: the beta-secretase enzyme in Alzheimer's disease

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12 December 2020

Amyloid-beta membrane binding and permeabilization are distinct processes influenced separately by membrane charge and fluidity

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12 December 2020

Cholesterol is an important factor affecting the membrane insertion of beta-amyloid peptide (A beta 1-40), which may potentially inhibit the fibril formation

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12 December 2020

Apoptosis signal-regulating kinase 1 in amyloid beta peptide-induced cerebral endothelial cell apoptosis.

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12 December 2020

Amyloid beta enhances cytosolic phospholipase A2 level and arachidonic acid release via nitric oxide in APP-transfected PC12 cells.

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12 December 2020

Promotion of oxidative lipid membrane damage by amyloid beta proteins

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12 December 2020

Membrane-bound β-amyloid oligomers are recruited into lipid rafts by a fyn-dependent mechanism

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12 December 2020

Mitochondrial Abeta: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease

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12 December 2020

The relationship between Abeta and memory in the Tg2576 mouse model of Alzheimer's disease.

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12 December 2020

Amyloid-beta proteins activate Ca(2+)-permeable channels through calcium-sensing receptors

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12 December 2020

Quantitation of lipid phases in phospholipid vesicles by the generalized polarization of Laurdan fluorescence

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12 December 2020

Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression

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12 December 2020

Phase fluctuation in phospholipid membranes revealed by Laurdan fluorescence

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12 December 2020

Increased collagen content of cerebral microvessels in Alzheimer's disease.

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12 December 2020

Neuronal endosomal/lysosomal membrane destabilization activates caspases and induces abnormal accumulation of the lipid secondary messenger ceramide.

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12 December 2020

Dysregulated IP3 signaling in cortical neurons of knock-in mice expressing an Alzheimer's-linked mutation in presenilin1 results in exaggerated Ca2+ signals and altered membrane excitability.

1 reference

12 December 2020

Mitochondria and vascular lesions as a central target for the development of Alzheimer's disease and Alzheimer disease-like pathology in transgenic mice

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12 December 2020

Amyloid-beta oligomers: their production, toxicity and therapeutic inhibition

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12 December 2020

Cytosolic phospholipase A2 mediates neuronal apoptosis induced by soluble oligomers of the amyloid-beta peptide

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12 December 2020

The interaction of beta-amyloid protein with cellular membranes stimulates its own production

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12 December 2020

Exploring interaction of β-amyloid segment (25–35) with membrane models through paramagnetic probes

1 reference

12 December 2020

The cell-selective neurotoxicity of the Alzheimer's Abeta peptide is determined by surface phosphatidylserine and cytosolic ATP levels. Membrane binding is required for Abeta toxicity.

1 reference

12 December 2020

Mechanism of membrane depolarization caused by the Alzheimer Abeta1-42 peptide

1 reference

12 December 2020

Membrane aging during cell growth ascertained by Laurdan generalized polarization

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12 December 2020

Membrane breakdown in acute and chronic neurodegeneration: focus on choline-containing phospholipids

1 reference

12 December 2020

Amyloid beta-peptide1-42 alters tight junction protein distribution and expression in brain microvessel endothelial cells

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12 December 2020

Neurovascular coupling in the normal brain and in hypertension, stroke, and Alzheimer disease

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12 December 2020

New therapeutic targets in the neurovascular pathway in Alzheimer's disease

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12 December 2020

Binding sites of amyloid beta-peptide in cell plasma membrane and implications for Alzheimer's disease

1 reference

12 December 2020

Cholesterol Modulates Amyloid Beta-peptide’s Membrane Interactions

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12 December 2020

Calcium signals induced by amyloid beta peptide and their consequences in neurons and astrocytes in culture

1 reference

12 December 2020

Two types of Alzheimer's beta-amyloid (1-40) peptide membrane interactions: aggregation preventing transmembrane anchoring versus accelerated surface fibril formation.

1 reference

12 December 2020

Neurovascular mechanisms and blood-brain barrier disorder in Alzheimer's disease

1 reference

12 December 2020

Arachidonic acid released by phospholipase A(2) activation triggers Ca(2+)-dependent apoptosis through the mitochondrial pathway

1 reference

12 December 2020

Amyloid beta protein-(1-42) forms calcium-permeable, Zn2+-sensitive channel

1 reference

12 December 2020

Soluble aggregates of the amyloid-beta peptide are trapped by serum albumin to enhance amyloid-beta activation of endothelial cells

1 reference

12 December 2020

Alzheimer's disease: cholesterol, membrane rafts, isoprenoids and statins

1 reference

12 December 2020

Phospholipase A2 is involved in muscarinic receptor-mediated sAPPalpha release independently of cyclooxygenase or lypoxygenase activity in SH-SY5Y cells

1 reference

12 December 2020

Beta-secretase processing of the Alzheimer's amyloid protein precursor (APP).

1 reference

12 December 2020

Cerebral arachidonate cascade in dementia: Alzheimer's disease and vascular dementia

1 reference

12 December 2020

Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction.

1 reference

12 December 2020

Impact of cholesterol level upon APP and BACE proximity and APP cleavage

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12 December 2020

Microglial response to amyloid plaques in APPsw transgenic mice

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12 December 2020

Expression of inflammatory genes induced by beta-amyloid peptides in human brain endothelial cells and in Alzheimer's brain is mediated by the JNK-AP1 signaling pathway.

1 reference

12 December 2020

Brain microvascular changes in Alzheimer's disease and other dementias.

1 reference

12 December 2020

Amyloid beta peptide and NMDA induce ROS from NADPH oxidase and AA release from cytosolic phospholipase A2 in cortical neurons

1 reference

12 December 2020

Alzheimer's disease: molecular understanding predicts amyloid-based therapeutics

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12 December 2020

Turning blood into brain: cells bearing neuronal antigens generated in vivo from bone marrow

1 reference

12 December 2020

Neurotoxic effect of oligomeric and fibrillar species of amyloid-beta peptide 1-42: involvement of endoplasmic reticulum calcium release in oligomer-induced cell death.

1 reference

12 December 2020

Modulation and dynamics of phase properties in phospholipid mixtures detected by Laurdan fluorescence

1 reference

12 December 2020

Endocytosis is required for synaptic activity-dependent release of amyloid-beta in vivo

1 reference

12 December 2020

Neuronal membrane cholesterol loss enhances amyloid peptide generation

1 reference

12 December 2020

Secondary structure conversions of Alzheimer's Abeta(1-40) peptide induced by membrane-mimicking detergents

1 reference

12 December 2020

Inflammatory cell adhesion molecules in ischemic cerebrovascular disease

1 reference

12 December 2020

Multiple membrane tethers probed by atomic force microscopy

1 reference

12 December 2020

Examining the levels of ganglioside and cholesterol in cell membrane on attenuation the cytotoxicity of beta-amyloid peptide

1 reference

12 December 2020

beta-Amyloid peptide induces formation of actin stress fibers through p38 mitogen-activated protein kinase

1 reference

12 December 2020

Gene expression profiling of 12633 genes in Alzheimer hippocampal CA1: transcription and neurotrophic factor down-regulation and up-regulation of apoptotic and pro-inflammatory signaling

1 reference

12 December 2020

Double-tether extraction from human umbilical vein and dermal microvascular endothelial cells

1 reference

12 December 2020

Mitochondrial failures in Alzheimer's disease

1 reference

12 December 2020

Association of vascular amyloid beta and cells of the mononuclear phagocyte system in hereditary cerebral hemorrhage with amyloidosis (Dutch) and Alzheimer disease.

1 reference

12 December 2020

The nature and effects of cortical microvascular pathology in aging and Alzheimer's disease

1 reference

12 December 2020

Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons

1 reference

12 December 2020

Acceleration of amyloid beta-peptide aggregation by physiological concentrations of calcium

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12 December 2020

Amyloid-beta peptide induces temporal membrane biphasic changes in astrocytes through cytosolic phospholipase A2.

1 reference

12 December 2020

NADPH-oxidase-derived reactive oxygen species mediate the cerebrovascular dysfunction induced by the amyloid beta peptide.

1 reference

12 December 2020

Membrane tether extraction from human umbilical vein endothelial cells and its implication in leukocyte rolling

1 reference

12 December 2020

Altered Ca2+ dependence of synaptosomal plasma membrane Ca2+-ATPase in human brain affected by Alzheimer's disease

1 reference

12 December 2020

Is Alzheimer's disease a neurodegenerative or a vascular disorder? Data, dogma, and dialectics

1 reference

12 December 2020

Inflammatory factors are elevated in brain microvessels in Alzheimer's disease

1 reference

12 December 2020

Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease

1 reference

12 December 2020

Histamine effects on endothelial cell fibronectin interaction studied by atomic force microscopy

1 reference

12 December 2020

Vascular remodeling versus amyloid beta-induced oxidative stress in the cerebrovascular dysfunctions associated with Alzheimer's disease.

1 reference

12 December 2020

Cellular membrane composition defines A beta-lipid interactions

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12 December 2020

Inhibition of phospholipase A2 activity reduces membrane fluidity in rat hippocampus

1 reference

12 December 2020

Amyloid beta-peptide induces cell monolayer albumin permeability, impairs glucose transport, and induces apoptosis in vascular endothelial cells.

1 reference

12 December 2020

Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease

1 reference

12 December 2020

Acute effect of fatty acids on metabolism and mitochondrial coupling in skeletal muscle.

1 reference

12 December 2020

Reactive microglia in patients with senile dementia of the Alzheimer type are positive for the histocompatibility glycoprotein HLA-DR.

1 reference

12 December 2020

Alzheimer disease amyloid beta protein forms calcium channels in bilayer membranes: blockade by tromethamine and aluminum

1 reference

12 December 2020

Diversity of group types, regulation, and function of phospholipase A2

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12 December 2020

Amyloid-beta promotes calcium influx and neurodegeneration via stimulation of L voltage-sensitive calcium channels rather than NMDA channels in cultured neurons

1 reference

12 December 2020

Protein oxidation and lipid peroxidation in brain of subjects with Alzheimer's disease: insights into mechanism of neurodegeneration from redox proteomics

1 reference

12 December 2020

Efficient inhibition of the Alzheimer's disease beta-secretase by membrane targeting

1 reference

12 December 2020

Lifetime of the P-selectin-carbohydrate bond and its response to tensile force in hydrodynamic flow.

1 reference

12 December 2020

Phospholipase A2-generated lipid mediators in the brain: the good, the bad, and the ugly

1 reference

12 December 2020

The role of phospholipase A2 in neuronal homeostasis and memory formation: implications for the pathogenesis of Alzheimer's disease

1 reference

12 December 2020

Brain-membrane cholesterol in Alzheimer's disease

1 reference

12 December 2020

Modulation of amyloid precursor protein cleavage by cellular sphingolipids

1 reference

12 December 2020

Amyloid beta peptide toxicity in differentiated PC12 cells: calpain-calpastatin, caspase, and membrane damage

1 reference

12 December 2020

Increased membrane cholesterol might render mature hippocampal neurons more susceptible to beta-amyloid-induced calpain activation and tau toxicity

1 reference

12 December 2020

Lipid rafts as a membrane-organizing principle

1 reference

12 December 2020

Phospholipid‐Metabolizing Enzymes in Alzheimer's Disease: Increased Lysophospholipid Acyltransferase Activity and Decreased Phospholipase A2 Activity

1 reference

12 December 2020

Association of gamma-secretase with lipid rafts in post-Golgi and endosome membranes

1 reference

12 December 2020

Cholesterol modulates the membrane-disordering effects of beta-amyloid peptides in the hippocampus: specific changes in Alzheimer's disease.

1 reference

12 December 2020

Interaction of free fatty acids with mitochondria: coupling, uncoupling and permeability transition

1 reference

12 December 2020

Soluble amyloid precursor protein alpha reduces neuronal injury and improves functional outcome following diffuse traumatic brain injury in rats

1 reference

12 December 2020

Amyloid beta peptide-induced cerebral endothelial cell death involves mitochondrial dysfunction and caspase activation

1 reference

12 December 2020

Lysosomal membrane damage in soluble Abeta-mediated cell death in Alzheimer's disease

1 reference

12 December 2020

Phospholipase A2 in the central nervous system: implications for neurodegenerative diseases

1 reference

12 December 2020

Amyloid beta protein (1-40) forms calcium-permeable, Zn2+-sensitive channel in reconstituted lipid vesicles

1 reference

12 December 2020

Induction of amyloid beta accumulation by ER calcium disruption and resultant upregulation of angiogenic factors in ARPE19 cells.

1 reference

12 December 2020

Lipid rafts as functional heterogeneity in cell membranes

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12 December 2020

Abeta-induced vascular oxidative stress and attenuation of functional hyperemia in mouse somatosensory cortex

1 reference

12 December 2020

The release of calcium from the endoplasmic reticulum induced by amyloid-beta and prion peptides activates the mitochondrial apoptotic pathway.

1 reference

12 December 2020

Cytosolic phospholipase A2 is induced in reactive glia following different forms of neurodegeneration

1 reference

12 December 2020

Comprehensive theory of Alzheimer's disease. The effects of cholesterol on membrane receptor trafficking.

1 reference

12 December 2020

Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins

1 reference

12 December 2020

The effect of cellular cholesterol on membrane-cytoskeleton adhesion

1 reference

12 December 2020

A lipid boundary separates APP and secretases and limits amyloid beta-peptide generation

1 reference

12 December 2020

Agrin and microvascular damage in Alzheimer’s disease

1 reference

12 December 2020

Amyloid beta-peptide1-40 increases neuronal membrane fluidity: role of cholesterol and brain region.

1 reference

12 December 2020