(Q37638190)

21 August 2017

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title

Naive T cell homeostasis: from awareness of space to a sense of place (English)

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21 August 2017

Kensuke Takada

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21 August 2017

Stephen C Jameson

series ordinal

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21 August 2017

publication date

1 December 2009

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Nature Reviews Immunology

21 August 2017

published in

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21 August 2017

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21 August 2017

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21 August 2017

page(s)

823-832

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MHC-dependent survival of naïve T cells? A complicated answer to a simple question

21 August 2017

cites work

1 reference

Maintaining the norm: T-cell homeostasis

31 March 2020

1 reference

Homeostasis of T cell numbers: from thymus production to peripheral compartmentalization and the indexation of regulatory T cells

31 March 2020

1 reference

Homeostasis of naive and memory T cells

31 March 2020

1 reference

Positive and negative selection of T cells

31 March 2020

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Preselection thymocytes are more sensitive to T cell receptor stimulation than mature T cells

31 March 2020

1 reference

Divergent changes in the sensitivity of maturing T cells to structurally related ligands underlies formation of a useful T cell repertoire

31 March 2020

1 reference

ZAP-70 is constitutively associated with tyrosine-phosphorylated TCR ζ in murine thymocytes and lymph node T cells

31 March 2020

1 reference

CD4+ T cell survival is not directly linked to self-MHC-induced TCR signaling

31 March 2020

1 reference

Tetracycline-controllable selection of CD4(+) T cells: half-life and survival signals in the absence of major histocompatibility complex class II molecules

31 March 2020

1 reference

Survival of mature CD4 T lymphocytes is dependent on major histocompatibility complex class II-expressing dendritic cells

31 March 2020

1 reference

Peripheral T cell survival requires continual ligation of the T cell receptor to major histocompatibility complex-encoded molecules

31 March 2020

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Death of peripheral CD8+ T cells in the absence of MHC class I is Fas-dependent and not blocked by Bcl-xL.

31 March 2020

1 reference

Long-term T cell memory requires the surface expression of self-peptide/major histocompatibility complex molecules

31 March 2020

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Persistence of memory CD8 T cells in MHC class I-deficient mice

31 March 2020

1 reference

MHC Class II Molecules Are Not Required for Survival of Newly Generated CD4+ T Cells, but Affect Their Long-Term Life Span

31 March 2020

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Differential requirements for survival and proliferation of CD8 naïve or memory T cells

31 March 2020

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Are major histocompatibility complex molecules involved in the survival of naive CD4+ T cells?

31 March 2020

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Survival and homeostatic proliferation of naive peripheral CD4+ T cells in the absence of self peptide:MHC complexes

31 March 2020

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MHC class II deprivation impairs CD4 T cell motility and responsiveness to antigen-bearing dendritic cells in vivo

31 March 2020

1 reference

Self-recognition is crucial for maintaining the peripheral CD4+ T-cell pool in a nonlymphopenic environment

31 March 2020

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Major histocompatibility complex (MHC) class I KbDb -/- deficient mice possess functional CD8+ T cells and natural killer cells

31 March 2020

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Self-class I MHC molecules support survival of naive CD8 T cells, but depress their functional sensitivity through regulation of CD8 expression levels

31 March 2020

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Naive and memory CD4+ T cell survival controlled by clonal abundance

31 March 2020

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Competition for self ligands restrains homeostatic proliferation of naive CD4 T cells

31 March 2020

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Spontaneous proliferation, a response of naive CD4 T cells determined by the diversity of the memory cell repertoire.

31 March 2020

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Cutting edge: homeostatic proliferation of peripheral T lymphocytes is regulated by clonal competition.

31 March 2020

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The role of TCR specificity and clonal competition during reconstruction of the peripheral T cell pool.

31 March 2020

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Naive CD4(+) T cell frequency varies for different epitopes and predicts repertoire diversity and response magnitude.

31 March 2020

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A role for TCR affinity in regulating naive T cell homeostasis.

31 March 2020

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The clone size of peripheral CD8 T cells is regulated by TCR promiscuity

31 March 2020

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T cell receptor contact to restricting MHC molecules is a prerequisite for peripheral interclonal T cell competition

31 March 2020

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Sensory adaptation in naive peripheral CD4 T cells

31 March 2020

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Fine tuning of TCR signaling by CD5.

31 March 2020

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How much TCR does a T cell need?

31 March 2020

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How alpha beta T cells deal with induced TCR alpha ablation

31 March 2020

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Long-Term Survival But Impaired Homeostatic Proliferation of Naive T Cells in the Absence of p56lck

31 March 2020

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TCR signals mediated by Src family kinases are essential for the survival of naive T cells

31 March 2020

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Self-recognition promotes the foreign antigen sensitivity of naive T lymphocytes

31 March 2020

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Agonist/endogenous peptide-MHC heterodimers drive T cell activation and sensitivity

31 March 2020

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T cell activation enhancement by endogenous pMHC acts for both weak and strong agonists but varies with differentiation state

31 March 2020

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A role for CD5 in TCR-mediated signal transduction and thymocyte selection

31 March 2020

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Cutting edge: differential self-peptide/MHC requirement for maintaining CD8 T cell function versus homeostatic proliferation.

31 March 2020

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Peripheral expression of self-MHC-II influences the reactivity and self-tolerance of mature CD4(+) T cells: evidence from a lymphopenic T cell model

31 March 2020

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Control of T cell viability

31 March 2020

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IL-7 enhances the survival and maintains the size of naive T cells

31 March 2020

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The role of thymic stromal lymphopoietin in CD8+ T cell homeostasis

31 March 2020

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T lymphocytes need IL-7 but not IL-4 or IL-6 to survive in vivo

31 March 2020

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Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo

31 March 2020

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IL-7 promotes the survival and maturation but not differentiation of human post-thymic CD4+ T cells

31 March 2020

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Interleukin 7 regulates the survival and generation of memory CD4 cells

31 March 2020

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IL-7 is critical for homeostatic proliferation and survival of naive T cells

31 March 2020

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IL-7 transgenic mice: analysis of the role of IL-7 in the differentiation of thymocytes in vivo and in vitro

31 March 2020

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Overexpression of interleukin (IL)-7 leads to IL-15-independent generation of memory phenotype CD8+ T cells

31 March 2020

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New insights into the regulation of T cells by gamma(c) family cytokines

31 March 2020

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Cell biology of IL-7, a key lymphotrophin

31 March 2020

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Bim/Bcl-2 balance is critical for maintaining naive and memory T cell homeostasis

31 March 2020

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Bcl-2 Rescues T Lymphopoiesis in Interleukin-7 Receptor–Deficient Mice

31 March 2020

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Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1-/- mice

31 March 2020

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Loss of Bim increases T cell production and function in interleukin 7 receptor-deficient mice

31 March 2020

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IL-7 promotes Glut1 trafficking and glucose uptake via STAT5-mediated activation of Akt to support T-cell survival

31 March 2020

1 reference

A brief introduction to FOXOlogy

31 March 2020

1 reference

Kruppel-like factor 2 regulates thymocyte and T-cell migration

31 March 2020

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Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking

31 March 2020

1 reference

Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor.

31 March 2020

1 reference

The many faces of IL-7: from lymphopoiesis to peripheral T cell maintenance

31 March 2020

1 reference

Cytokine requirements for acute and Basal homeostatic proliferation of naive and memory CD8+ T cells

31 March 2020

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Administration of rhIL-7 in humans increases in vivo TCR repertoire diversity by preferential expansion of naive T cell subsets

31 March 2020

1 reference

Human recent thymic emigrants--identification, expansion, and survival characteristics

31 March 2020

1 reference

IL-7 differentially regulates cell cycle progression and HIV-1-based vector infection in neonatal and adult CD4+ T cells

31 March 2020

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Murine neonatal recent thymic emigrants are phenotypically and functionally distinct from adult recent thymic emigrants

31 March 2020

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IL-7 promotes T cell proliferation through destabilization of p27Kip1.

31 March 2020

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IL-7-induced proliferation of recent thymic emigrants requires activation of the PI3K pathway

31 March 2020

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Suppression of IL7Rα Transcription by IL-7 and Other Prosurvival Cytokines

31 March 2020

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'Coreceptor tuning': cytokine signals transcriptionally tailor CD8 coreceptor expression to the self-specificity of the TCR.

31 March 2020

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Variation in interleukin 7 receptor α chain (IL7R) influences risk of multiple sclerosis

31 March 2020

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The transcriptional repressor Gfi1 affects development of early, uncommitted c-Kit+ T cell progenitors and CD4/CD8 lineage decision in the thymus

31 March 2020

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An essential role of the Forkhead-box transcription factor Foxo1 in control of T cell homeostasis and tolerance

31 March 2020

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The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism

31 March 2020

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An intense form of homeostatic proliferation of naive CD8+ cells driven by IL-2

31 March 2020

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Stromal cell networks regulate lymphocyte entry, migration, and territoriality in lymph nodes

31 March 2020

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Stromal cell contributions to the homeostasis and functionality of the immune system.

31 March 2020

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Cutting edge: Secondary lymphoid organs are essential for maintaining the CD4, but not CD8, naive T cell pool

31 March 2020

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Autologous regulation of naive T cell homeostasis within the T cell compartment.

31 March 2020

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Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells.

31 March 2020

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Coexpression of the chemokines ELC and SLC by T zone stromal cells and deletion of the ELC gene in the plt/plt mouse

31 March 2020

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CC chemokine receptor 7 contributes to Gi-dependent T cell motility in the lymph node

31 March 2020

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CCR7 ligands stimulate the intranodal motility of T lymphocytes in vivo

31 March 2020

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Chemokines, sphingosine-1-phosphate, and cell migration in secondary lymphoid organs

31 March 2020

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S1P1 receptor signaling overrides retention mediated by G alpha i-coupled receptors to promote T cell egress

31 March 2020

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Characterization of the thymic IL-7 niche in vivo.

31 March 2020

1 reference

Interleukin 7 signaling in dendritic cells regulates the homeostatic proliferation and niche size of CD4+ T cells.

31 March 2020

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Chemokine C receptor 7 expression and protection of circulating CD8+ T lymphocytes from apoptosis

31 March 2020

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T cell homeostasis requires G protein-coupled receptor-mediated access to trophic signals that promote growth and inhibit chemotaxis

31 March 2020

1 reference

Interaction of interleukin 7 (IL-7) with glycosaminoglycans and its biological relevance

31 March 2020

1 reference

Chemokines in innate and adaptive host defense: basic chemokinese grammar for immune cells

31 March 2020

1 reference

Rulers over randomness: stroma cells guide lymphocyte migration in lymph nodes

31 March 2020

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Viral targeting of fibroblastic reticular cells contributes to immunosuppression and persistence during chronic infection

31 March 2020

1 reference

Regulation of Homeostatic Chemokine Expression and Cell Trafficking During Immune Responses

31 March 2020

1 reference

Lymphoid stroma in the initiation and control of immune responses.

31 March 2020

1 reference

Restoration of lymphoid organ integrity through the interaction of lymphoid tissue-inducer cells with stroma of the T cell zone.

31 March 2020

1 reference

31 March 2020

What's new in the Aire?

1 reference

Peripheral antigen display by lymph node stroma promotes T cell tolerance to intestinal self

31 March 2020

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Deletional tolerance mediated by extrathymic Aire-expressing cells

31 March 2020

1 reference

The role of the thymus and recent thymic migrants in the maintenance of the adult peripheral lymphocyte pool

31 March 2020

1 reference

Control of recent thymic emigrant survival by positive selection signals and early growth response gene 1.

31 March 2020

1 reference

Age-dependent incidence, time course, and consequences of thymic renewal in adults

31 March 2020

1 reference

The many important facets of T-cell repertoire diversity

31 March 2020

1 reference

Increased production of IL-7 accompanies HIV-1-mediated T-cell depletion: implications for T-cell homeostasis

31 March 2020

1 reference

IL-7/anti-IL-7 mAb complexes restore T cell development and induce homeostatic T Cell expansion without lymphopenia

31 March 2020

1 reference

Cytokines and T-cell homeostasis

31 March 2020

1 reference

Modulating T-cell homeostasis with IL-7: preclinical and clinical studies.

31 March 2020

1 reference

CD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity

31 March 2020

1 reference

MHC class I is required for peripheral accumulation of CD8+ thymic emigrants.

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19935802

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Heparan sulfate proteoglycans mediate interleukin-7-dependent B lymphopoiesis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19935802

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRI2657

1 reference

21 August 2017

1 reference