(Q36698672)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8248238%20AND%20SRC:MED&resulttype=core&format=json

27 October 2019

title

Analysis of the human alpha-globin gene cluster in transgenic mice (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8248238%20AND%20SRC:MED&resulttype=core&format=json

27 October 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8248238%20AND%20SRC:MED&resulttype=core&format=json

27 October 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8248238%20AND%20SRC:MED&resulttype=core&format=json

27 October 2019

J A Sharpe

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8248238%20AND%20SRC:MED&resulttype=core&format=json

27 October 2019

E Whitelaw

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8248238%20AND%20SRC:MED&resulttype=core&format=json

27 October 2019

D R Higgs

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8248238%20AND%20SRC:MED&resulttype=core&format=json

27 October 2019

W G Wood

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8248238%20AND%20SRC:MED&resulttype=core&format=json

27 October 2019

language of work or name

English

0 references

publication date

1 December 1993

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8248238%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

27 October 2019

published in

1 reference

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27 October 2019

volume

1 reference

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27 October 2019

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8248238%20AND%20SRC:MED&resulttype=core&format=json

27 October 2019

page(s)

11262-11266

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8248238%20AND%20SRC:MED&resulttype=core&format=json

Position-independent, high-level expression of the human beta-globin gene in transgenic mice

27 October 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47962

Evidence for a locus activation region: the formation of developmentally stable hypersensitive sites in globin-expressing hybrids

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47962

Gamma delta beta-thalassemia due to a de novo mutation deleting the 5' beta-globin gene activation-region hypersensitive sites

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47962

Molecular analysis of the human beta-globin locus activation region

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47962

An erythroid-specific, developmental-stage-independent enhancer far upstream of the human "beta-like globin" genes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47962

A review of the molecular genetics of the human alpha-globin gene cluster

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47962

DNA sequences regulating human globin gene transcription in nondeletional hereditary persistence of fetal hemoglobin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47962

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47962

DNaseI hypersensitive sites 1, 2 and 3 of the human beta-globin dominant control region direct position-independent expression

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47962

Detailed analysis of the site 3 region of the human beta-globin dominant control region

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47962

Developmental regulation of the human zeta globin gene in transgenic mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47962

The 5'HS2 of the globin locus control region enhances transcription through the interaction of a multimeric complex binding at two functionally distinct NF-E2 binding sites

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47962

Characterization of the major regulatory element upstream of the human alpha-globin gene cluster

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47962

δβ Thalassemia and Hereditary Persistence of Fetal Hemoglobin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47962

Human alpha-globin genes demonstrate autonomous developmental regulation in transgenic mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47962

Inactivation of human alpha-globin gene expression by a de novo deletion located upstream of the alpha-globin gene cluster

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47962

In vivo footprinting of the human alpha-globin locus upstream regulatory element by guanine and adenine ligation-mediated polymerase chain reaction

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47962

The developmental regulation of the human zeta-globin gene in transgenic mice employing beta-galactosidase as a reporter gene

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47962

Analysis of the human alpha globin upstream regulatory element (HS-40) in transgenic mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47962

A single point mutation is the cause of the Greek form of hereditary persistence of fetal haemoglobin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47962

A single beta-globin locus control region element (5' hypersensitive site 2) is sufficient for developmental regulation of human globin genes in transgenic mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47962

The chromosomal arrangement of human alpha-like globin genes: sequence homology and alpha-globin gene deletions

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47962

Recombination at the human alpha-globin gene cluster: sequence features and topological constraints

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47962

A dominant control region from the human beta-globin locus conferring integration site-independent gene expression

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47962

Developmental regulation of a complete 70-kb human beta-globin locus in transgenic mice

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47962

Regulation of human embryonic globin genes zeta 2 and epsilon in stably transformed mouse erythroleukemia cells

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47962

Identification of two distinct regulatory regions adjacent to the human β-interferon gene

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47962

Alpha-thalassemia caused by a large (62 kb) deletion upstream of the human alpha globin gene cluster

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47962

A truncated human chromosome 16 associated with α thalassaemia is stabilized by addition of telomeric repeat (TTAGGG)n

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47962

Role of upstream DNase I hypersensitive sites in the regulation of human alpha globin gene expression

20 October 2018

1 reference

12 December 2020

β-Globin gene inactivation by DNA translocation in γβ-thalassaemi

1 reference

12 December 2020

Rapid reprogramming of globin gene expression in transient heterokaryons

1 reference

12 December 2020

A major positive regulatory region located far upstream of the human alpha-globin gene locus

1 reference

12 December 2020

Alpha-thalassemia resulting from deletion of regulatory sequences far upstream of the alpha-globin structural genes.

1 reference

12 December 2020

In situ hybridization reveals co-expression of embryonic and adult alpha globin genes in the earliest murine erythrocyte progenitors

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.90.23.11262

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8248238%20AND%20SRC:MED&resulttype=core&format=json

27 October 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8248238%20AND%20SRC:MED&resulttype=core&format=json

27 October 2019

PubMed publication ID

8248238

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8248238%20AND%20SRC:MED&resulttype=core&format=json