(Q36814647)

English

A single beta-globin locus control region element (5' hypersensitive site 2) is sufficient for developmental regulation of human globin genes in transgenic mice

scientific article published on May 1, 1992

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Europe PubMed Central

PMC publication ID

16 August 2017

A single beta-globin locus control region element (5' hypersensitive site 2) is sufficient for developmental regulation of human globin genes in transgenic mice (English)

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1373805

19 September 2022

regulation of gene expression

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1373805

19 September 2022

regulatory sequence

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1373805

19 September 2022

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1373805

19 September 2022

multigene family

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1373805

19 September 2022

Caroline A Abbott

2

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C. A. Abbott

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1373805

19 September 2022

author name string

Chan-Thomas PS

5

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16 August 2017

B. J. Morley

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1373805

19 September 2022

J. A. Sharpe

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1373805

19 September 2022

J. Lida

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1373805

19 September 2022

P. S. Chan-Thomas

5

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19 September 2022

W. G. Wood

6

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19 September 2022

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publication date

1 May 1992

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Europe PubMed Central

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16 August 2017

full work available at URL

http://mcb.asm.org/cgi/content/abstract/12/5/2057

online access status

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1373805

19 September 2022

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1373805/?tool=EBI

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1373805

19 September 2022

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1373805/pdf/?tool=EBI

Portable Document Format

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1373805

19 September 2022

https://europepmc.org/articles/PMC364377

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Europe PubMed Central

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1373805

19 September 2022

https://europepmc.org/articles/PMC364377?pdf=render

Portable Document Format

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Europe PubMed Central

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1373805

19 September 2022

Molecular and Cellular Biology

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

12

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

5

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

2057-2066

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Activation of human beta-globin genes from nonerythroid cells by fusion with murine erythroleukemia cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364377

29 September 2017

The "beta-like-globin" gene domain in human erythroid cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364377

29 September 2017

Position-independent, high-level expression of the human beta-globin gene in transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364377

29 September 2017

Evidence for a locus activation region: the formation of developmentally stable hypersensitive sites in globin-expressing hybrids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364377

29 September 2017

Two 3' sequences direct adult erythroid-specific expression of human beta-globin genes in transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364377

29 September 2017

Human beta-globin gene expression in transgenic mice is enhanced by a distant DNase I hypersensitive site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364377

29 September 2017

Molecular analysis of the human beta-globin locus activation region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364377

29 September 2017

A point mutation in the A gamma-globin gene promoter in Greek hereditary persistence of fetal haemoglobin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364377

29 September 2017

The human beta-globin locus activation region alters the developmental fate of a human fetal globin gene in transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364377

29 September 2017

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364377

29 September 2017

DNaseI hypersensitive sites 1, 2 and 3 of the human beta-globin dominant control region direct position-independent expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364377

29 September 2017

Detailed analysis of the site 3 region of the human beta-globin dominant control region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364377

29 September 2017

The beta-globin dominant control region: hypersensitive site 2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364377

29 September 2017

Definition of the minimal requirements within the human beta-globin gene and the dominant control region for high level expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364377

29 September 2017

Structure and function of the enhancer 3' to the human A gamma globin gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364377

29 September 2017

Beta-globin locus activation regions: conservation of organization, structure, and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364377

29 September 2017

Conservation of the primary structure, organization, and function of the human and mouse beta-globin locus-activating regions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364377

29 September 2017

Review: Stratton Lecture 1990. Clinical implications of positive and negative hematopoietic stem cell regulators.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364377

29 September 2017

Negative regulation of globin gene expression during megakaryocytic differentiation of a human erythroleukemic cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364377

29 September 2017

Hypersensitive site 4 of the human beta globin locus control region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364377

29 September 2017

Human beta-globin locus control region: analysis of the 5' DNase I hypersensitive site HS 2 in transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364377

29 September 2017

The 5'HS2 of the globin locus control region enhances transcription through the interaction of a multimeric complex binding at two functionally distinct NF-E2 binding sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364377

29 September 2017

Regulated expression of globin chains and the erythroid transcription factor GATA-1 during erythropoiesis in the developing mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364377

29 September 2017

Selective activation of human β - but not γ-globin gene in human fibroblast × mouse erythroleukaemia cell hybrids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364377

29 September 2017

An embryonic pattern of expression of a human fetal globin gene in transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364377

27 June 2018

Regulated expression of human A gamma-, beta-, and hybrid gamma beta-globin genes in transgenic mice: manipulation of the developmental expression patterns.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364377

27 June 2018

Developmental regulation of beta-globin gene switching.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364377

27 June 2018

A dominant control region from the human beta-globin locus conferring integration site-independent gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364377

27 June 2018

Developmental regulation of human fetal-to-adult globin gene switching in transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364377

27 June 2018

Primary structure of the goat beta-globin locus control region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364377

27 June 2018

Postnatal transition of γ-globin gene expression in normal Japanese population

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364377

27 June 2018

Importance of globin gene order for correct developmental expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364377

27 June 2018

Human gamma- to beta-globin gene switching in transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364377

27 June 2018

Identification of two distinct regulatory regions adjacent to the human β-interferon gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364377

5 September 2018

Analysis of human hemoglobin switching in MEL x human fetal erythroid cell hybrids.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=364377

5 September 2018

Human γ-globin genes silenced independently of other genes in the β-globin locus

1 reference

https://pubmed.ncbi.nlm.nih.gov/1373805

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A major positive regulatory region located far upstream of the human alpha-globin gene locus

1 reference

https://pubmed.ncbi.nlm.nih.gov/1373805

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The beta-globin stage selector element factor is erythroid-specific promoter/enhancer binding protein NF-E4

1 reference

https://pubmed.ncbi.nlm.nih.gov/1373805

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The beta-globin dominant control region activates homologous and heterologous promoters in a tissue-specific manner

1 reference

https://pubmed.ncbi.nlm.nih.gov/1373805

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A single erythroid-specific DNase I super-hypersensitive site activates high levels of human beta-globin gene expression in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/1373805

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid reprogramming of globin gene expression in transient heterokaryons

1 reference

https://pubmed.ncbi.nlm.nih.gov/1373805

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Developmental regulation of a cloned adult β-globin gene in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/1373805

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.12.5.2057

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

10.1128/MCB.12.5.2057-2066.1992

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1373805

19 September 2022

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

ResearchGate publication ID

0 references

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