(Q35763658)

10 August 2017

title

Estrogen Receptor-β Up-Regulates IGF1R Expression and Activity to Inhibit Apoptosis and Increase Growth of Medulloblastoma (English)

1 reference

10 August 2017

0 references

Clifford J Cookman

1 reference

10 August 2017

Scott M Belcher

series ordinal

1 reference

10 August 2017

language of work or name

English

0 references

publication date

17 April 2015

1 reference

10 August 2017

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10 August 2017

volume

156

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10 August 2017

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10 August 2017

page(s)

2395-2408

1 reference

The therapeutic role of fulvestrant in the management of patients with hormone receptor-positive breast cancer.

10 August 2017

cites work

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2 October 2017

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2 October 2017

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The insulin-like growth factor-I receptor kinase inhibitor NVP-ADW742 sensitizes medulloblastoma to the effects of chemotherapy

2 October 2017

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Rapid Signaling Actions of Environmental Estrogens in Developing Granule Cell Neurons Are Mediated by Estrogen Receptor β

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Blockade of estrogen receptor signaling inhibits growth and migration of medulloblastoma

2 October 2017

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Crosstalk between IGF1R and estrogen receptor signaling in breast cancer.

2 October 2017

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Tumor suppressor gene co-operativity in compound Patched1 and suppressor of fused heterozygous mutant mice

2 October 2017

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2 October 2017

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Estrogen receptor regulates insulin-like growth factor-I receptor gene expression in breast tumor cells: involvement of transcription factor Sp1.

2 October 2017

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Cross-talk between IGF-I and estradiol in the brain: focus on neuroprotection

2 October 2017

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2 October 2017

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Evidence that the mouse insulin receptor substrate-1 belongs to the gene family on which the promoter is activated by estrogen receptor alpha through its interaction with Sp1.

2 October 2017

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Ontogeny of rapid estrogen-mediated extracellular signal-regulated kinase signaling in the rat cerebellar cortex: potent nongenomic agonist and endocrine disrupting activity of the xenoestrogen bisphenol A.

2 October 2017

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Insulin-like growth factor II is involved in the proliferation control of medulloblastoma and its cerebellar precursor cells

2 October 2017

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ACTH deficiency in childhood cancer survivors

2 October 2017

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Late neurocognitive sequelae in survivors of brain tumours in childhood

2 October 2017

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ERbeta exerts multiple stimulative effects on human breast carcinoma cells

2 October 2017

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Sonic hedgehog and insulin-like growth factor signaling synergize to induce medulloblastoma formation from nestin-expressing neural progenitors in mice

2 October 2017

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Estrogen receptor expression in a human primitive neuroectodermal tumor cell line from the cerebral cortex: estrogen stimulates rapid ERK1/2 activation and receptor-dependent cell migration

2 October 2017

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Tamoxifen modulation of etoposide cytotoxicity involves inhibition of protein kinase C activity and insulin-like growth factor II expression in brain tumor cells

2 October 2017

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2 October 2017

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Insulin receptor substrate-2 deficiency impairs brain growth and promotes tau phosphorylation

2 October 2017

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2 October 2017

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Hormones and hormone antagonists: mechanisms of action in carcinogenesis of endometrial and breast cancer

2 October 2017

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The IGF/IGFBP system in CNS malignancy

2 October 2017

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2 October 2017

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Crosstalk between the insulin-like growth factors and estrogens in breast cancer.

2 October 2017

1 reference

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2 October 2017

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Altered neural cell fates and medulloblastoma in mouse patched mutants

2 October 2017

1 reference

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Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP.

2 October 2017

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2 October 2017

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Protective role of 17 β-estradiol on medulloblastoma development in Patched 1 heterozygous mice

2 October 2017

1 reference

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Rapid estrogenic regulation of extracellular signal- regulated kinase 1/2 signaling in cerebellar granule cells involves a G protein- and protein kinase A-dependent mechanism and intracellular activation of protein phosphatase 2A.

12 July 2018

1 reference

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High incidence of medulloblastoma following X-ray-irradiation of newborn Ptc1 heterozygous mice

12 July 2018

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Concomitant induction of apoptosis and necrosis in cerebellar granule cells following serum and potassium withdrawal.

12 July 2018

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In vivo actions of insulin-like growth factor-I (IGF-I) on cerebellum development in transgenic mice: evidence that IGF-I increases proliferation of granule cell progenitors

12 July 2018

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Harmful effect of ERβ on BCRP-mediated drug resistance and cell proliferation in ERα/PR-negative breast cancer.

12 July 2018

1 reference

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Estrogen and insulin-like growth factor 1 synergistically promote the development of lung adenocarcinoma in mice

25 September 2018

1 reference

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The estrogen receptor beta agonist diarylpropionitrile (DPN) inhibits medulloblastoma development via anti-proliferative and pro-apototic pathways.

25 September 2018

1 reference

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Partial neuroprotection by 17-β-estradiol in neonatal γ-irradiated rat cerebellum.

25 September 2018

1 reference

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Blockade of estrogen receptor signaling to improve outlook for medulloblastoma sufferers.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475721

From childhood to adulthood: long-term outcome of medulloblastoma patients. The Institut Curie experience (1980-2000).

25 September 2018

1 reference

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Insulin-like growth factor-I protects granule neurons from apoptosis and improves ataxia in weaver mice

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475721

Estrogens and ICI182,780 (Faslodex) modulate mitosis and cell death in immature cerebellar neurons via rapid activation of p44/p42 mitogen-activated protein kinase.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475721

Inhibition of insulin-like growth factor I activity contributes to the premature apoptosis of cerebellar granule neuron in weaver mutant mice: in vitro analysis

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475721

Insulin-like growth factor I receptor activity in human medulloblastomas.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475721

Activation of the IGF-IR system contributes to malignant growth of human and mouse medulloblastomas.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475721

Insulin-like growth factor-I overexpression attenuates cerebellar apoptosis by altering the expression of Bcl family proteins in a developmentally specific manner.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475721

Loss of p53 but not ARF accelerates medulloblastoma in mice heterozygous for patched.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475721

Estrogen receptor beta immunoreactivity in differentiating cells of the developing rat cerebellum

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475721

Regulated expression of estrogen receptor alpha and beta mRNA in granule cells during development of the rat cerebellum

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475721

Insulin-like growth factor I prevents the development of sensitivity to kainate neurotoxicity in cerebellar granule cells

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25885794

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Interactions of estrogens and insulin-like growth factor-I in the brain: implications for neuroprotection

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25885794

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Estrogen receptor analyses. Correlation of biochemical and immunohistochemical methods using monoclonal antireceptor antibodies

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25885794

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1210/EN.2015-1141

1 reference

10 August 2017

1 reference

10 August 2017

1 reference