(Q35196245)

7 August 2017

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title

Endoplasmic reticulum: a primary target in various acute disorders and degenerative diseases of the brain (English)

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7 August 2017

main subject

endoplasmic reticulum

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author name string

Wulf Paschen

series ordinal

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7 August 2017

language of work or name

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1 October 2003

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7 August 2017

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7 August 2017

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7 August 2017

issue

4-5

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7 August 2017

page(s)

365-383

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Cell damage in the brain: a speculative synthesis

7 August 2017

cites work

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7 January 2021

Calcium Dependence of Toxic Cell Death: A Final Common Pathway

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7 January 2021

Calcium-related damage in ischemia

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7 January 2021

Bcl-2 potentiates the maximal calcium uptake capacity of neural cell mitochondria

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7 January 2021

Role of Ca2+ channels in the ability of membrane depolarization to prevent neuronal death induced by trophic-factor deprivation: evidence that levels of internal Ca2+ determine nerve growth factor dependence of sympathetic ganglion cells

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7 January 2021

Evidence that nerve growth factor dependence of sympathetic neurons for survival in vitro may be determined by levels of cytoplasmic free Ca2+.

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7 January 2021

Programmed cell death: its possible contribution to neurotoxicity mediated by calcium channel antagonists

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7 January 2021

L-type voltage-gated calcium channels modulate kainic acid neurotoxicity in cerebellar granule cells

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7 January 2021

Reduction in intracellular calcium levels induces injury in developing neurons

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7 January 2021

Distinct influx pathways, not calcium load, determine neuronal vulnerability to calcium neurotoxicity.

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7 January 2021

Disturbances of calcium homeostasis within the endoplasmic reticulum may contribute to the development of ischemic-cell damage

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7 January 2021

Disturbances of the functioning of endoplasmic reticulum: a key mechanism underlying neuronal cell injury?

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7 January 2021

Role of calcium in neuronal cell injury: which subcellular compartment is involved?

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7 January 2021

Dependence of vital cell function on endoplasmic reticulum calcium levels: implications for the mechanisms underlying neuronal cell injury in different pathological states

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7 January 2021

Endoplasmic reticulum dysfunction--a common denominator for cell injury in acute and degenerative diseases of the brain?

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7 January 2021

Neuronal and glial calcium signaling in Alzheimer's disease

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7 January 2021

Technique for in situ measurement of calcium in intracellular inositol 1,4,5-trisphosphate-sensitive stores using the fluorescent indicator mag-fura-2.

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7 January 2021

Activity-Dependent Calcium Sequestration in Dendrites of Hippocampal Neurons in Brain Slices

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7 January 2021

Thapsigargin, a Ca(2+)-ATPase inhibitor, depletes the intracellular Ca2+ pool and induces apoptosis in human hepatoma cells

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7 January 2021

Thapsigargin-induced persistent intracellular calcium pool depletion and apoptosis in human hepatoma cells

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7 January 2021

Ca2+ ionophore-induced apoptosis on cultured embryonic rat cortical neurons

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7 January 2021

Cyclosporin A rescues thymocytes from apoptosis induced by very low concentrations of thapsigargin: effects on mitochondrial function

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7 January 2021

Roles of cytoplasmic Ca2+ and intracellular Ca2+ stores in induction and suppression of apoptosis in S49 cells

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7 January 2021

Mouse Lymphoma Cells Destined to Undergo Apoptosis in Response to Thapsigargin Treatment Fail to Generate a Calcium-mediatedgrp78/grp94Stress Response

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7 January 2021

Baculovirus p35 and Z-VAD-fmk inhibit thapsigargin-induced apoptosis of breast cancer cells

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7 January 2021

Apoptotic cell death and CPP32-like activation induced by thapsigargin and their prevention by nerve growth factor in PC12 cells

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7 January 2021

Apoptosis in insulin-secreting cells. Evidence for the role of intracellular Ca2+ stores and arachidonic acid metabolism

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7 January 2021

Role of intracellular calcium stores in cell death from oxygen-glucose deprivation in a neuronal cell line

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7 January 2021

Release and sequestration of calcium by ryanodine‐sensitive stores in rat hippocampal neurones

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7 January 2021

Neuronal calcium signaling

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7 January 2021

Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls

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https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

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7 January 2021

The effect of ischaemia and recirculation on protein synthesis in the rat brain

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7 January 2021

Resuscitation of the monkey brain after one hour complete ischemia. III. Indications of metabolic recovery

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7 January 2021

Phosphorylation of the alpha subunit of initiation factor 2 correlates with the inhibition of translation following transient cerebral ischaemia in the rat.

1 reference

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7 January 2021

Global brain ischemia and reperfusion: modifications in eukaryotic initiation factors associated with inhibition of translation initiation

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7 January 2021

Changes in the phosphorylation of initiation factor eIF-2alpha, elongation factor eEF-2 and p70 S6 kinase after transient focal cerebral ischaemia in mice.

1 reference

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7 January 2021

Mechanisms underlying suppression of protein synthesis induced by transient focal cerebral ischemia in mouse brain

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7 January 2021

Activation of MYD116 (gadd34) expression following transient forebrain ischemia of rat: implications for a role of disturbances of endoplasmic reticulum calcium homeostasis

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7 January 2021

Effects of Ca2+ and ionophore A23187 on protein synthesis in intact rabbit reticulocytes

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7 January 2021

Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans development

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7 January 2021

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

1 reference

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7 January 2021

IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

1 reference

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7 January 2021

Relation of neuronal endoplasmic reticulum calcium homeostasis to ribosomal aggregation and protein synthesis: implications for stress-induced suppression of protein synthesis

1 reference

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7 January 2021

Activation of heme oxygenase-1 expression by disturbance of endoplasmic reticulum calcium homeostasis in rat neuronal cell culture

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7 January 2021

Role of calcium in the activation of erp72 and heme oxygenase-1 expression on depletion of endoplasmic reticulum calcium stores in rat neuronal cell culture

1 reference

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7 January 2021

Brain ischemia and reperfusion activates the eukaryotic initiation factor 2alpha kinase, PERK.

1 reference

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7 January 2021

Transient cerebral ischemia activates processing of xbp1 messenger RNA indicative of endoplasmic reticulum stress

1 reference

https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Induction of glucose regulated protein (grp78) and inducible heat shock protein (hsp70) mRNAs in rat brain after kainic acid seizures and focal ischemia

1 reference

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7 January 2021

Differential induction of mRNA species encoding several classes of stress proteins following focal cerebral ischemia in rats

1 reference

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7 January 2021

Increased expression of mRNA encoding calbindin-D28K, the glucose-regulated proteins, or the 72 kDa heat-shock protein in three models of acute CNS injury

1 reference

https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Erp72 expression activated by transient cerebral ischemia or disturbance of neuronal endoplasmic reticulum calcium stores

1 reference

https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Activation of gadd153 expression through transient cerebral ischemia: evidence that ischemia causes endoplasmic reticulum dysfunction

1 reference

https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Molecular cloning of a novel member of the HSP110 family of genes, ischemia-responsive protein 94 kDa (irp94), expressed in rat brain after transient forebrain ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Ischemia-responsive protein (irp94) is up-regulated by endoplasmic reticulum stress

1 reference

https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Stress-associated endoplasmic reticulum protein 1 (SERP1)/Ribosome-associated membrane protein 4 (RAMP4) stabilizes membrane proteins during stress and facilitates subsequent glycosylation

1 reference

https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Oxidative stress-associated impairment of proteasome activity during ischemia-reperfusion injury

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https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Protein aggregation after transient cerebral ischemia.

1 reference

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7 January 2021

Down-regulation of parkin protein in transient focal cerebral ischemia: A link between stroke and degenerative disease?

1 reference

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7 January 2021

Involvement of Intracellular Calcium Stores during Oxygen/Glucose Deprivation in Striatal Large Aspiny Interneurons

1 reference

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7 January 2021

Global ischemia-induced inhibition of the coupling ratio of calcium uptake and ATP hydrolysis by rat whole brain microsomal Mg(2+)/Ca(2+) ATPase

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7 January 2021

Neuroprotective nitric oxide synthase inhibitor reduces intracellular calcium accumulation following transient global ischemia in the gerbil

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7 January 2021

Effect of nitric oxide on endoplasmic reticulum calcium homeostasis, protein synthesis and energy metabolism

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7 January 2021

Effects of hypoxanthine-xanthine oxidase on Ca2+ stores and protein synthesis in human endothelial cells

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7 January 2021

The oxidative inactivation of sarcoplasmic reticulum Ca(2+)-ATPase by peroxynitrite

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7 January 2021

Peroxidative stress selectively down-regulates the neuronal stress response activated under conditions of endoplasmic reticulum dysfunction

1 reference

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7 January 2021

Mobilization of dantrolene-sensitive intracellular calcium pools is involved in the cytotoxicity induced by quisqualate and N-methyl-D-aspartate but not by 2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionate and kainate in cultured cerebral cortic

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7 January 2021

Dantrolene protects against ischemic, delayed neuronal death in gerbil brain

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7 January 2021

Selective proteasomal dysfunction in the hippocampal CA1 region after transient forebrain ischemia

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7 January 2021

Protein aggregation after focal brain ischemia and reperfusion

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7 January 2021

Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity

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7 January 2021

Impairment of the ubiquitin-proteasome system by protein aggregation

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7 January 2021

Proteasome inhibition leads to a heat-shock response, induction of endoplasmic reticulum chaperones, and thermotolerance

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7 January 2021

ER stress response: getting the UPR hand on misfolded proteins

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7 January 2021

Proteasome inhibitor induced gene expression profiles reveal overexpression of transcriptional regulators ATF3, GADD153 and MAD1.

1 reference

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7 January 2021

Kainic acid‐induced seizures and brain damage in the rat: Role of calcium homeostasis

1 reference

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7 January 2021

Neuroprotective effects of early vs. late administration of dantrolene in experimental status epilepticus

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7 January 2021

Pilocarpine-induced status epilepticus causes N-methyl-D-aspartate receptor-dependent inhibition of microsomal Mg(2+)/Ca(2+) ATPase-mediated Ca(2+) uptake

1 reference

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7 January 2021

Bicuculline increases Ca2+ transients in rat cerebellar granule cells through non-GABA(A) receptor associated mechanisms

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7 January 2021

Morphological astrocytic changes in complicated human brain trauma. A light and electron microscopic study

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7 January 2021

Signaling pathways between the plasma membrane and endoplasmic reticulum calcium stores

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7 January 2021

Regulation of mitochondrial metabolism by ER Ca2+ release: an intimate connection

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7 January 2021

Apoptotic crosstalk between the endoplasmic reticulum and mitochondria controlled by Bcl-2

1 reference

https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Endoplasmic reticulum stress-induced cell death requires mitochondrial membrane permeabilization

1 reference

https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

BH-3-only BIK functions at the endoplasmic reticulum to stimulate cytochrome c release from mitochondria

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https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Transmission of cell stress from endoplasmic reticulum to mitochondria: enhanced expression of Lon protease

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7 January 2021

Manganese Superoxide Dismutase Affects Cytochrome c Release and Caspase-9 Activation After Transient Focal Cerebral Ischemia in Mice

1 reference

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7 January 2021

Factors influencing the processing and function of the amyloid beta precursor protein--a potential therapeutic target in Alzheimer's disease?

1 reference

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7 January 2021

Calcium signaling in the ER: its role in neuronal plasticity and neurodegenerative disorders

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7 January 2021

Dysregulation of cellular calcium homeostasis in Alzheimer's disease: bad genes and bad habits

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7 January 2021

Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease

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7 January 2021

The endoplasmic reticulum as an integrating signalling organelle: from neuronal signalling to neuronal death

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https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

The role of the ubiquitin-proteasomal pathway in Parkinson's disease and other neurodegenerative disorders

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https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response

1 reference

https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Characterization of mouse Ire1 alpha: cloning, mRNA localization in the brain and functional analysis in a neural cell line

1 reference

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7 January 2021

Upregulation of BiP and CHOP by the unfolded-protein response is independent of presenilin expression.

1 reference

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7 January 2021

FAD-linked presenilin-1 mutants impede translation regulation under ER stress.

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https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Alzheimer's disease-associated reduction of polysomal mRNA translation

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https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Ultrastructural analysis of beta-amyloid-induced apoptosis in cultured hippocampal neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Neurotrophic factors [activity-dependent neurotrophic factor (ADNF) and basic fibroblast growth factor (bFGF)] interrupt excitotoxic neurodegenerative cascades promoted by a PS1 mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Ca(2+) stores and capacitative Ca(2+) entry in human neuroblastoma (SH-SY5Y) cells expressing a familial Alzheimer's disease presenilin-1 mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Beyond the Qs in the polyglutamine diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Length of huntingtin and its polyglutamine tract influences localization and frequency of intracellular aggregates

1 reference

https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Polyglutamine aggregates stimulate ER stress signals and caspase-12 activation

1 reference

https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats

1 reference

https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

1 reference

https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1

1 reference

https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Astrocytic but not neuronal increased expression and redistribution of parkin during unfolded protein stress

1 reference

https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

The sarco/endoplasmic reticulum calcium-ATPase 2b is an endoplasmic reticulum stress-inducible protein

1 reference

https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Ischemic depolarization monitoring: evaluation of protein synthesis in the hippocampal CA1 after brief unilateral ischemia in a gerbil model

1 reference

https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Cerebral protein synthesis and ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Persistent inhibition of protein synthesis precedes delayed neuronal death in postischemic gerbil hippocampus

1 reference

https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Evidence supporting a role for programmed cell death in focal cerebral ischemia in rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Global ischemia can cause DNA fragmentation indicative of apoptosis in rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Internucleosomal DNA cleavage involved in ischemia-induced neuronal death

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https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Apoptosis after experimental stroke: fact or fashion?

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https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Neurodegenerative disorders and ischemic brain diseases.

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https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Programmed cell death in cerebral ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Perk is essential for translational regulation and cell survival during the unfolded protein response

1 reference

https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival

1 reference

https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Endoplasmic reticulum stress-mediated apoptosis in pancreatic beta-cells

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https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Endoplasmic reticulum stress proteins block oxidant-induced Ca2+ increases and cell death.

1 reference

https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: suppression of oxidative stress and stabilization of calcium homeostasis

1 reference

https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Calcium-dependent regulation of protein synthesis in intact mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Hypothermic treatment restores glucose regulated protein 78 (GRP78) expression in ischemic brain

1 reference

https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Immunohistochemical detection of Bax and Bcl-2 proteins in gerbil hippocampus following transient forebrain ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

Apoptosis repressor genes Bcl-2 and Bcl-x-long are expressed in the rat brain following global ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0143-4160%2803%2900139-8

7 January 2021

10.1016/S0143-4160(03)00139-8

Identifiers

DOI

1 reference

release_ar6dfynjwzgexm5657n54y3stq

7 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ar6dfynjwzgexm5657n54y3stq

24 November 2022

mapped directly with Wikidata item

1 reference