(Q35024457)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25485927%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

title

Copper-zinc superoxide dismutase-mediated redox regulation of bortezomib resistance in multiple myeloma (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25485927%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25485927%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Kelley Salem

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25485927%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Michael L McCormick

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25485927%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Erik Wendlandt

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25485927%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Apollina Goel

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25485927%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

publication date

18 November 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25485927%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25485927%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25485927%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

page(s)

23-33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25485927%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

24 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4309843/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Where we were, where we are, where we are going: progress in multiple myeloma

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8 July 2018

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8 July 2018

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8 July 2018

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Pivotal Advance: Protein synthesis modulates responsiveness of differentiating and malignant plasma cells to proteasome inhibitors

8 July 2018

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8 July 2018

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Lymphoma cells with increased anti-oxidant defenses acquire chemoresistance

8 July 2018

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Interleukin-6 counteracts therapy-induced cellular oxidative stress in multiple myeloma by up-regulating manganese superoxide dismutase

8 July 2018

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Disulfiram, an old drug with new potential therapeutic uses for human hematological malignancies.

8 July 2018

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Manipulation of cellular redox parameters for improving therapeutic responses in B-cell lymphoma and multiple myeloma

8 July 2018

1 reference

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Impaired bortezomib binding to mutant β5 subunit of the proteasome is the underlying basis for bortezomib resistance in leukemia cells.

8 July 2018

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SOD1 Transcriptional and Posttranscriptional Regulation and Its Potential Implications in ALS

8 July 2018

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Targeting malignancies with disulfiram (Antabuse): multidrug resistance, angiogenesis, and proteasome.

8 July 2018

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Two endoplasmic reticulum PDI peroxidases increase the efficiency of the use of peroxide during disulfide bond formation

8 July 2018

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Dexamethasone-induced oxidative stress enhances myeloma cell radiosensitization while sparing normal bone marrow hematopoiesis

8 July 2018

1 reference

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Bortezomib-resistant myeloma cell lines: a role for mutated PSMB5 in preventing the accumulation of unfolded proteins and fatal ER stress

8 July 2018

1 reference

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Pharmacokinetic and pharmacodynamic study of two doses of bortezomib in patients with relapsed multiple myeloma

8 July 2018

1 reference

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Post-translational modifications of superoxide dismutase

8 July 2018

1 reference

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Adaptation to oxidative stress, chemoresistance, and cell survival

8 July 2018

1 reference

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Acquisition of a multidrug-resistant phenotype with a proteasome inhibitor in multiple myeloma

8 July 2018

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8 July 2018

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Targeted inhibition of the immunoproteasome is a potent strategy against models of multiple myeloma that overcomes resistance to conventional drugs and nonspecific proteasome inhibitors

8 July 2018

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Increased levels of superoxide and H2O2 mediate the differential susceptibility of cancer cells versus normal cells to glucose deprivation

8 July 2018

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8 July 2018

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8 July 2018

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Molecular basis of bortezomib resistance: proteasome subunit beta5 (PSMB5) gene mutation and overexpression of PSMB5 protein

8 July 2018

1 reference

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Redox regulation of cell survival

8 July 2018

1 reference

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Proteasome beta subunit pharmacogenomics: gene resequencing and functional genomics

8 July 2018

1 reference

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The histone deacetylase inhibitor, PXD101, potentiates bortezomib-induced anti-multiple myeloma effect by induction of oxidative stress and DNA damage

8 July 2018

1 reference

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Clinical impact of bortezomib in frontline regimens for patients with multiple myeloma

8 July 2018

1 reference

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Image-based screening for the identification of novel proteasome inhibitors

8 July 2018

1 reference

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Mitochondrial mutations in cancer

8 July 2018

1 reference

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Synergistic activity of the proteasome inhibitor PS-341 with non-myeloablative 153-Sm-EDTMP skeletally targeted radiotherapy in an orthotopic model of multiple myeloma

8 July 2018

1 reference

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Correlates of imexon sensitivity in human multiple myeloma cell lines

8 July 2018

1 reference

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PS-341-mediated selective targeting of multiple myeloma cells by synergistic increase in ionizing radiation-induced apoptosis

8 July 2018

1 reference

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Synergistic induction of oxidative injury and apoptosis in human multiple myeloma cells by the proteasome inhibitor bortezomib and histone deacetylase inhibitors

8 July 2018

1 reference

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Alpha-synuclein up-regulation and aggregation during MPP+-induced apoptosis in neuroblastoma cells: intermediacy of transferrin receptor iron and hydrogen peroxide

8 July 2018

1 reference

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Chromosomal DNA fragmentation in apoptosis and necrosis induced by oxidative stress

8 July 2018

1 reference

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Phase II trial of tetrathiomolybdate in patients with advanced kidney cancer

8 July 2018

1 reference

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A fraction of yeast Cu,Zn-superoxide dismutase and its metallochaperone, CCS, localize to the intermembrane space of mitochondria. A physiological role for SOD1 in guarding against mitochondrial oxidative damage.

8 July 2018

1 reference

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Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple

8 July 2018

1 reference

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The role of cellular glutathione peroxidase redox regulation in the suppression of tumor cell growth by manganese superoxide dismutase

8 July 2018

1 reference

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Treatment of metastatic cancer with tetrathiomolybdate, an anticopper, antiangiogenic agent: Phase I study.

8 July 2018

1 reference

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Tissue-specific functions of individual glutathione peroxidases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309843

Glutathione peroxidase compensates for the hypersensitivity of Cu,Zn-superoxide dismutase overproducers to oxidant stress

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309843

Importance of Se-glutathione peroxidase, catalase, and Cu/Zn-SOD for cell survival against oxidative stress

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309843

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309843

Structure and mechanism of copper, zinc superoxide dismutase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309843

Bypasses of the antimycin a block of mitochondrial electron transport in relation to ubisemiquinone function.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309843

Potentiation of nitrogen mustard cytotoxicity by disulfiram, diethyldithiocarbamic acid, and diethylamine in mice

8 July 2018

1 reference

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Alteration of endogenous glutathione peroxidase, manganese superoxide dismutase, and glutathione transferase activity in cells transfected with a copper-zinc superoxide dismutase expression vector. Explanation for variations in paraquat resistance

8 July 2018

1 reference

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The balance between copper-zinc superoxide dismutase and catalase affects the sensitivity of mouse epidermal cells to oxidative stress

8 July 2018

1 reference

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8 July 2018

Superoxide dismutases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309843

Glutathione peroxidase activity in selenium-deficient rat liver

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309843

Role of superoxide dismutase in cancer: a review

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309843

Oxidizing to death: disulfiram for cancer cell killing

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309843

Increase of novel biomarkers for oxidative stress in patients with plasma cell disorders and in multiple myeloma patients with bone lesions.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309843

Study of antioxidant levels in patients with multiple myeloma.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309843

The proteasome load versus capacity balance determines apoptotic sensitivity of multiple myeloma cells to proteasome inhibition.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309843

Point mutation of the proteasome beta5 subunit gene is an important mechanism of bortezomib resistance in bortezomib-selected variants of Jurkat T cell lymphoblastic lymphoma/leukemia line

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309843

Redox homeostasis modulates the sensitivity of myeloma cells to bortezomib

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309843

High-risk myeloma: a gene expression based risk-stratification model for newly diagnosed multiple myeloma treated with high-dose therapy is predictive of outcome in relapsed disease treated with single-agent bortezomib or high-dose dexamethasone.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309843

A validated gene expression model of high-risk multiple myeloma is defined by deregulated expression of genes mapping to chromosome 1.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309843

No evidence of mutations of the PSMB5 (beta-5 subunit of proteasome) in a case of myeloma with clinical resistance to Bortezomib

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309843

High-sensitivity cytotoxicity assays for nonadherent cells.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309843

Oxidant/antioxidant parameters and their relationship with medical treatment in multiple myeloma.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309843

The proteasome inhibitor bortezomib promotes mitochondrial injury and apoptosis induced by the small molecule Bcl-2 inhibitor HA14-1 in multiple myeloma cells

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309843

Molecular mechanisms mediating antimyeloma activity of proteasome inhibitor PS-341.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309843

Effect of geranylgeranylaceton on cellular damage induced by proteasome inhibition in cultured spinal neurons

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309843

Overexpression of copper zinc superoxide dismutase suppresses human glioma cell growth

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309843

An assay for superoxide dismutase activity in mammalian tissue homogenates

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309843

Degradation of Amyotrophic Lateral Sclerosis-linked Mutant Cu,Zn-Superoxide Dismutase Proteins by Macroautophagy and the Proteasome

25 October 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309843

25 October 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309843

DNA strand scission and free radical production in menadione-treated cells. Correlation with cytotoxicity and role of NADPH quinone acceptor oxidoreductase

9 December 2018

1 reference

12 December 2020

[Lipid peroxidation and activity of antioxidative enzymes in patients with multiple myeloma]

1 reference

12 December 2020

Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine

1 reference

12 December 2020

Oxidative stress-associated impairment of proteasome activity during ischemia-reperfusion injury

1 reference

12 December 2020

Nonprofit drugs as the salvation of the world's healthcare systems: the case of Antabuse (disulfiram)

1 reference

12 December 2020

Expression of transfected human CuZn superoxide dismutase gene in mouse L cells and NS20Y neuroblastoma cells induces enhancement of glutathione peroxidase activity

1 reference

12 December 2020

A randomized phase II study of cisplatin alone versus cisplatin plus disulfiram

1 reference

12 December 2020

10.1016/J.REDOX.2014.11.002

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25485927%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25485927%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

PubMed publication ID

25485927

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25485927%20AND%20SRC:MED&resulttype=core&format=json