(Q35064623)

6 August 2017

title

SIRT1 deficiency downregulates PTEN/JNK/FOXO1 pathway to block reactive oxygen species-induced apoptosis in mouse embryonic stem cells (English)

1 reference

6 August 2017

SIRT1 Deficiency Downregulates PTEN/JNK/FOXO1 Pathway to Block Reactive Oxygen Species-Induced Apoptosis in Mouse Embryonic Stem Cells (English)

1 reference

Crossref

https://api.crossref.org/works/10.1089/SCD.2010.0465

28 August 2024

main subject

reactive oxygen species

1 reference

1 reference

Hal E Broxmeyer

1 reference

6 August 2017

Hee-Don Chae

1 reference

6 August 2017

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21083429

28 August 2024

publication date

3 January 2011

1 reference

full work available at URL

6 August 2017

https://europepmc.org/articles/pmc3121936?pdf=render

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21083429

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21083429/?tool=EBI

28 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21083429

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21083429/pdf/?tool=EBI

28 August 2024

file format

Portable Document Format

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21083429

https://europepmc.org/articles/PMC3121936

28 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21083429

https://europepmc.org/articles/PMC3121936?pdf=render

28 August 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21083429

https://doi.org/10.1089/scd.2010.0465

28 August 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21083429

https://www.liebertpub.com/doi/full-xml/10.1089/scd.2010.0465

28 August 2024

1 reference

Crossref

https://api.crossref.org/works/10.1089/SCD.2010.0465

https://www.liebertpub.com/doi/pdf/10.1089/scd.2010.0465

28 August 2024

1 reference

Crossref

https://api.crossref.org/works/10.1089/SCD.2010.0465

Stem Cells and Development

28 August 2024

published in

1 reference

6 August 2017

1 reference

6 August 2017

1 reference

6 August 2017

page(s)

1277-1285

1 reference

Reactive oxygen species enhance differentiation of human embryonic stem cells into mesendodermal lineage

6 August 2017

cites work

1 reference

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c-Jun NH2-terminal kinase is required for lineage-specific differentiation but not stem cell self-renewal

8 July 2018

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Reactive oxygen species, cellular redox systems, and apoptosis

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Nuclear Akt interacts with B23/NPM and protects it from proteolytic cleavage, enhancing cell survival

8 July 2018

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PTEN and the PI3-kinase pathway in cancer

8 July 2018

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PTEN acetylation modulates its interaction with PDZ domain

8 July 2018

1 reference

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Sir2 mediates apoptosis through JNK-dependent pathways in Drosophila

8 July 2018

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Regulation of pro-apoptotic BH3-only proteins and its contribution to cancer progression and chemoresistance

8 July 2018

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Function of reactive oxygen species during animal development: passive or active?

8 July 2018

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Tenets of PTEN tumor suppression

8 July 2018

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8 July 2018

1 reference

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SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121936

PTEN nuclear localization is regulated by oxidative stress and mediates p53-dependent tumor suppression

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121936

Cell cycle-dependent nuclear export of phosphatase and tensin homologue tumor suppressor is regulated by the phosphoinositide-3-kinase signaling cascade

8 July 2018

1 reference

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ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis

8 July 2018

1 reference

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The BH3-only protein Puma plays an essential role in cytokine deprivation induced apoptosis of mast cells

8 July 2018

1 reference

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Stressing the role of FoxO proteins in lifespan and disease

8 July 2018

1 reference

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SIRT2 deacetylates FOXO3a in response to oxidative stress and caloric restriction

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121936

Mouse embryonic stem cells are hypersensitive to apoptosis triggered by the DNA damage O(6)-methylguanine due to high E2F1 regulated mismatch repair

8 July 2018

1 reference

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PTEN enters the nuclear age.

8 July 2018

1 reference

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RhoH GTPase recruits and activates Zap70 required for T cell receptor signaling and thymocyte development

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121936

PCAF modulates PTEN activity

8 July 2018

1 reference

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Nuclear localization of PTEN by a Ran-dependent mechanism enhances apoptosis: Involvement of an N-terminal nuclear localization domain and multiple nuclear exclusion motifs

8 July 2018

1 reference

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Regulation of the PTEN phosphatase

8 July 2018

1 reference

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Acetylation of Foxo1 alters its DNA-binding ability and sensitivity to phosphorylation

8 July 2018

1 reference

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Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases

8 July 2018

1 reference

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p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression

8 July 2018

1 reference

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FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK.

8 July 2018

1 reference

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Stress defense in murine embryonic stem cells is superior to that of various differentiated murine cells

8 July 2018

1 reference

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JNK: a key modulator of intracellular signaling

8 July 2018

1 reference

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Multilineage differentiation from human embryonic stem cell lines

8 July 2018

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8 July 2018

1 reference

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

8 July 2018

1 reference

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The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121936

Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121936

Derivation of completely cell culture-derived mice from early-passage embryonic stem cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121936

The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121936

FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121936

The absence of SIR2alpha protein has no effect on global gene silencing in mouse embryonic stem cells.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121936

AP1-mediated transcriptional enhancement of the rat tyrosine hydroxylase gene by muscarinic stimulation

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21083429

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Hsp90-Akt phosphorylates ASK1 and inhibits ASK1-mediated apoptosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21083429

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Chemical genetic analysis of the time course of signal transduction by JNK

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21083429

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

1 reference

6 August 2017

1 reference

6 August 2017

1 reference