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English
Modes of p53 regulation
scientific article (publication date: 15 May 2009)
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Europe PubMed Central
title
Modes of p53 regulation
(English)
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PubMed
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=19450511
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30 April 2017
author name string
Kruse JP
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1
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30 April 2017
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series ordinal
2
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English
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30 April 2017
publication date
15 May 2009
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30 April 2017
published in
Cell
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30 April 2017
volume
137
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30 April 2017
issue
4
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page(s)
609-22
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retrieved
30 April 2017
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30 April 2017
A large-scale RNAi screen in human cells identifies new components of the p53 pathway
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Unbiased mapping of transcription factor binding sites along human chromosomes 21 and 22 points to widespread regulation of noncoding RNAs
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30 April 2017
Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis
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Ribosomal Protein L11 Negatively Regulates Oncoprotein MDM2 and Mediates a p53-Dependent Ribosomal-Stress Checkpoint Pathway
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Regulation of HDM2 activity by the ribosomal protein L11
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p53 has a direct apoptogenic role at the mitochondria
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Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation
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30 April 2017
Mdm4 (Mdmx) regulates p53-induced growth arrest and neuronal cell death during early embryonic mouse development
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30 April 2017
Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization
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ASPP proteins specifically stimulate the apoptotic function of p53
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30 April 2017
hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase
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30 April 2017
Negative control of p53 by Sir2alpha promotes cell survival under stress
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30 April 2017
Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53
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30 April 2017
Translating the Histone Code
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30 April 2017
Post-translational modifications and activation of p53 by genotoxic stresses
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30 April 2017
Deacetylation of p53 modulates its effect on cell growth and apoptosis
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30 April 2017
PML regulates p53 acetylation and premature senescence induced by oncogenic Ras
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30 April 2017
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30 April 2017
Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53
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30 April 2017
The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites
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30 April 2017
Nucleolar Arf sequesters Mdm2 and activates p53
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A novel human SRB/MED-containing cofactor complex, SMCC, involved in transcription regulation
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p53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage
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30 April 2017
Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53
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30 April 2017
DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2
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30 April 2017
Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain
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30 April 2017
Regulation of p53 stability by Mdm2
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30 April 2017
Mdm2 promotes the rapid degradation of p53
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30 April 2017
p53, the cellular gatekeeper for growth and division
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30 April 2017
Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations
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30 April 2017
Two cellular proteins that bind to wild-type but not mutant p53
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30 April 2017
p53 transcriptional activation mediated by coactivators TAFII40 and TAFII60
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30 April 2017
Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53
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30 April 2017
Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
30 April 2017
Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
30 April 2017
Identification of p53 as a sequence-specific DNA-binding protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
30 April 2017
Cancer. p53, guardian of the genome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
30 April 2017
Definition of a consensus binding site for p53
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
30 April 2017
T antigen is bound to a host protein in SY40-transformed cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
30 April 2017
Oncogenic viral protein HPV E7 up-regulates the SIRT1 longevity protein in human cervical cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
KRAB-type zinc-finger protein Apak specifically regulates p53-dependent apoptosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
MSL2 promotes Mdm2-independent cytoplasmic localization of p53
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
Mdm2 and Mdm4 loss regulates distinct p53 activities
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
The role of ubiquitination in the direct mitochondrial death program of p53.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
The ARF/oncogene pathway activates p53 acetylation within the DNA binding domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
Crippling p53 activities via knock-in mutations in mouse models
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
C-terminal modifications regulate MDM2 dissociation and nuclear export of p53.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
Tip60-dependent acetylation of p53 modulates the decision between cell-cycle arrest and apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
The Mdm2 RING domain C-terminus is required for supramolecular assembly and ubiquitin ligase activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
Acetylation of mouse p53 at lysine 317 negatively regulates p53 apoptotic activities after DNA damage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
Binding of p53 to the central domain of Mdm2 is regulated by phosphorylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
Ser18 and 23 phosphorylation is required for p53-dependent apoptosis and tumor suppression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
Distinct p53 acetylation cassettes differentially influence gene-expression patterns and cell fate.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
Excess HDM2 impacts cell cycle and apoptosis and has a selective effect on p53-dependent transcription.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
Mouse bites dogma: how mouse models are changing our views of how P53 is regulated in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
Transcriptional regulation by p53: one protein, many possibilities
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
Keeping p53 in check: essential and synergistic functions of Mdm2 and Mdm4.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
An shRNA barcode screen provides insight into cancer cell vulnerability to MDM2 inhibitors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
Ubiquitination of p53 at multiple sites in the DNA-binding domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
Small-molecule MDM2 antagonists reveal aberrant p53 signaling in cancer: implications for therapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
WT p53, but not tumor-derived mutants, bind to Bcl2 via the DNA binding domain and induce mitochondrial permeabilization.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
The central region of HDM2 provides a second binding site for p53.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
The C-terminal lysines fine-tune P53 stress responses in a mouse model but are not required for stability control or transactivation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
Functional analysis of the roles of posttranslational modifications at the p53 C terminus in regulating p53 stability and activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
Small molecule inhibitors of HDM2 ubiquitin ligase activity stabilize and activate p53 in cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
Mdmx as an essential regulator of p53 activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
The RING domain of Mdm2 mediates histone ubiquitylation and transcriptional repression.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
Defective apoptosis and B-cell lymphomas in mice with p53 point mutation at Ser 23.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
The p53 response to DNA damage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
Yin Yang 1 is a negative regulator of p53.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
p300/CBP and cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
Accelerated MDM2 auto-degradation induced by DNA-damage kinases is required for p53 activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
Inhibition of p53 degradation by Mdm2 acetylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
Phosphorylation of serine 18 regulates distinct p53 functions in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
Mono- versus polyubiquitination: differential control of p53 fate by Mdm2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
Cell type- and promoter-specific roles of Ser18 phosphorylation in regulating p53 responses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
The p53-Mdm2 module and the ubiquitin system.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
SUMO-1 and p53.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
The PTEN, Mdm2, p53 tumor suppressor-oncoprotein network
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
Mutation of mouse p53 Ser23 and the response to DNA damage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
Chromatin immunoprecipitation analysis fails to support the latency model for regulation of p53 DNA binding activity in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
C-terminal ubiquitination of p53 contributes to nuclear export
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
Kinetics of p53 binding to promoter sites in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
p300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
The N terminus of p53 regulates its dissociation from DNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
Stress signals utilize multiple pathways to stabilize p53
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
Influence of promoter DNA topology on sequence-specific DNA binding and transactivation by tumor suppressor p53.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
p53 and human cancer: the first ten thousand mutations.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
DNA damage induced p53 stabilization: no indication for an involvement of p53 phosphorylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
The p53 proto-oncogene can act as a suppressor of transformation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
Wild-type but not mutant p53 immunopurified proteins bind to sequences adjacent to the SV40 origin of replication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
Regulation of the specific DNA binding function of p53
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
Detection of a transformation-related antigen in chemically induced sarcomas and other transformed cells of the mouse
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
3 June 2018
SnapShot: p53 posttranslational modifications
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
26 November 2018
Acetylation of the p53 DNA-binding domain regulates apoptosis induction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
26 November 2018
Mdm2 is critically and continuously required to suppress lethal p53 activity in vivo.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
26 November 2018
The p53QS transactivation-deficient mutant shows stress-specific apoptotic activity and induces embryonic lethality
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
26 November 2018
Acetylation of p53 inhibits its ubiquitination by Mdm2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
26 November 2018
Latent and active p53 are identical in conformation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
26 November 2018
Transcriptional regulation by p53 through intrinsic DNA/chromatin binding and site-directed cofactor recruitment.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
26 November 2018
Stabilization of p53 by p14ARF without relocation of MDM2 to the nucleolus.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3737742
retrieved
26 November 2018
Facilitated search for specific genomic targets by p53 C-terminal basic DNA binding domain
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19450511
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Dual-site regulation of MDM2 E3-ubiquitin ligase activity
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19450511
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.CELL.2009.04.050
2 references
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=19450511
retrieved
30 April 2017
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
633424
OpenCitations bibliographic resource ID
633424
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
633424
PMC publication ID
3737742
2 references
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=19450511
retrieved
30 April 2017
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
633424
PubMed publication ID
19450511
2 references
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=19450511
retrieved
30 April 2017
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
633424
ResearchGate publication ID
24435350
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