(Q34412072)

2 August 2017

title

Probing ion-channel pores one proton at a time (English)

1 reference

2 August 2017

Gisela D Cymes

1 reference

2 August 2017

Ying Ni

series ordinal

1 reference

2 August 2017

Claudio Grosman

series ordinal

1 reference

2 August 2017

language of work or name

English

0 references

publication date

1 December 2005

1 reference

2 August 2017

1 reference

inferred from page(s)

published in

Nature

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2 August 2017

volume

438

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2 August 2017

issue

7070

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2 August 2017

page(s)

975-980

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A model of the closed form of the nicotinic acetylcholine receptor m2 channel pore

2 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1384014

A fluorophore attached to nicotinic acetylcholine receptor beta M2 detects productive binding of agonist to the alpha delta site

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1384014

Restoration of single-channel currents using the segmental k-means method based on hidden Markov modeling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1384014

Loose protein packing around the extracellular half of the GABA(A) receptor beta1 subunit M2 channel-lining segment

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1384014

Free-energy landscapes of ion-channel gating are malleable: changes in the number of bound ligands are accompanied by changes in the location of the transition state in acetylcholine-receptor channels

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1384014

A cytoplasmic region determines single-channel conductance in 5-HT3 receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1384014

Structure and gating mechanism of the acetylcholine receptor pore

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1384014

A model of the glycine receptor deduced from Brownian dynamics studies

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1384014

Cation-selective mutations in the M2 domain of the inhibitory glycine receptor channel reveal determinants of ion-charge selectivity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1384014

Structure of the transition state of gating in the acetylcholine receptor channel pore: a phi-value analysis.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1384014

What are the dielectric "constants" of proteins and how to validate electrostatic models?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1384014

Gating of inward-rectifier K+ channels by intracellular pH.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1384014

Mapping the conformational wave of acetylcholine receptor channel gating

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1384014

Single channel currents at six microsecond resolution elicited by acetylcholine in mouse myoballs.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1384014

Electrostatics and the ion selectivity of ligand-gated channels

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1384014

The location of the gate in the acetylcholine receptor channel

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1384014

Estimating single-channel kinetic parameters from idealized patch-clamp data containing missed events

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1384014

VMD: visual molecular dynamics

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1384014

Contribution of the S4 segment to gating charge in the Shaker K+ channel.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1384014

Molecular determinants of Ca2+ selectivity and ion permeation in L-type Ca2+ channels

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1384014

Classical electrostatics in biology and chemistry

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1384014

Congenital myasthenic syndrome caused by prolonged acetylcholine receptor channel openings due to a mutation in the M2 domain of the epsilon subunit

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1384014

Direct measurement of proton transfer rates to a group controlling the dihydropyridine-sensitive Ca2+ channel

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1384014

Structural and thermodynamic consequences of burying a charged residue within the hydrophobic core of T4 lysozyme

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1384014

The permeation pathway of neurotransmitter-gated ion channels

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1384014

Calcium channel characteristics conferred on the sodium channel by single mutations

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1384014

Electrostatic effects in proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1384014

Rings of negatively charged amino acids determine the acetylcholine receptor channel conductance

6 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04293

Electrostatic tuning of Mg2+ affinity in an inward-rectifier K+ channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04293

Role of outer ring carboxylates of the rat skeletal muscle sodium channel pore in proton block

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04293

Voltage-sensing residues in the S2 and S4 segments of the Shaker K+ channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04293

The role of hydrophobic microenvironments in modulating pKa shifts in proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04293

Gating-enhanced accessibility of hydrophobic sites within the transmembrane region of the nicotinic acetylcholine receptor's {delta}-subunit. A time-resolved photolabeling study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04293

Identification of acetylcholine receptor channel-lining residues in the entire M2 segment of the alpha subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04293

Protein mobility and GABA-induced conformational changes in GABA(A) receptor pore-lining M2 segment

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1384014

Acetylcholine receptor channel imaged in the open state

27 October 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04293

Two Identical Noninteracting Sites in an Ion Channel Revealed by Proton Transfer

21 January 2018

1 reference

12 December 2020

Agonist-induced changes in the structure of the acetylcholine receptor M2 regions revealed by photoincorporation of an uncharged nicotinic noncompetitive antagonist

1 reference

12 December 2020

Mutational analysis of the charge selectivity filter of the alpha7 nicotinic acetylcholine receptor

1 reference

12 December 2020

Local dynamics of the M13 major coat protein in different membrane-mimicking systems

1 reference

12 December 2020

Electrostatic basis of valence selectivity in cationic channels

1 reference

12 December 2020

Identifiers

DOI

10.1038/NATURE04293

1 reference

Dimensions Publication ID

2 August 2017

0 references

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2 August 2017

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