(Q34622832)

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Free-energy landscapes of ion-channel gating are malleable: changes in the number of bound ligands are accompanied by changes in the location of the transition state in acetylcholine-receptor channels

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1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Free-energy landscapes of ion-channel gating are malleable: changes in the number of bound ligands are accompanied by changes in the location of the transition state in acetylcholine-receptor channels (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

energy landscape

1 reference

based on heuristic

inferred from title

author name string

Claudio Grosman

1

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

language of work or name

0 references

publication date

1 December 2003

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

42

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

50

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

14977-14987

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Evidence for sequential barriers and obligatory intermediates in apparent two-state protein folding

1 reference

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Phi value analysis of heterogeneity in pathways of allosteric transitions: Evidence for parallel pathways of ATP-induced conformational changes in a GroEL ring

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463891

7 July 2018

Structure of the transition state of gating in the acetylcholine receptor channel pore: a phi-value analysis.

1 reference

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7 July 2018

Emerging structure of the nicotinic acetylcholine receptors

1 reference

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7 July 2018

Accurate computer-based design of a new backbone conformation in the second turn of protein L

1 reference

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7 July 2018

The dissociation of acetylcholine from open nicotinic receptor channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463891

7 July 2018

Constructing, verifying, and dissecting the folding transition state of chymotrypsin inhibitor 2 with all-atom simulations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463891

7 July 2018

Computer-based redesign of a protein folding pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463891

7 July 2018

The extracellular linker of muscle acetylcholine receptor channels is a gating control element

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463891

7 July 2018

Asymmetric and independent contribution of the second transmembrane segment 12' residues to diliganded gating of acetylcholine receptor channels: a single-channel study with choline as the agonist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463891

7 July 2018

Kinetic, mechanistic, and structural aspects of unliganded gating of acetylcholine receptor channels: a single-channel study of second transmembrane segment 12' mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463891

7 July 2018

Mapping the transition state of the WW domain beta-sheet.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463891

7 July 2018

Mapping the conformational wave of acetylcholine receptor channel gating

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463891

7 July 2018

Denaturant-induced movement of the transition state of protein folding revealed by high-pressure stopped-flow measurements

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463891

7 July 2018

Structural changes in the transition state of protein folding: alternative interpretations of curved chevron plots

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463891

7 July 2018

A re-examination of adult mouse nicotinic acetylcholine receptor channel activation kinetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463891

7 July 2018

Different folding transition states may result in the same native structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463891

7 July 2018

Estimating single-channel kinetic parameters from idealized patch-clamp data containing missed events

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463891

7 July 2018

Molecular dissection of subunit interfaces in the acetylcholine receptor: identification of residues that determine curare selectivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463891

7 July 2018

Application of physical organic chemistry to engineered mutants of proteins: Hammond postulate behavior in the transition state of protein folding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463891

7 July 2018

Transverse distance between the membrane and the agonist binding sites on the Torpedo acetylcholine receptor: a fluorescence study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463891

7 July 2018

Mechanisms of activation of muscle nicotinic acetylcholine receptors and the time course of endplate currents.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463891

7 July 2018

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463891

7 July 2018

On the application of "a plausible model" of allosteric proteins to the receptor for acetylcholine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463891

7 July 2018

Mapping the transition state and pathway of protein folding by protein engineering

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463891

7 July 2018

Perfection of a synaptic receptor: kinetics and energetics of the acetylcholine receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463891

7 July 2018

Kinetics of unliganded acetylcholine receptor channel gating

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463891

7 July 2018

Fast events in single-channel currents activated by acetylcholine and its analogues at the frog muscle end-plate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463891

7 July 2018

Application of linear free energy relations to protein conformational changes: the quaternary structural change of hemoglobin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463891

7 July 2018

Isotope effects and structure-reactivity correlations in the yeast alcohol dehydrogenase reaction. A study of the enzyme-catalyzed oxidation of aromatic alcohols

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463891

7 July 2018

Parameters for the Description of Transition States

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463891

26 October 2018

Hammond behavior versus ground state effects in protein folding: evidence for narrow free energy barriers and residual structure in unfolded states

1 reference

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26 October 2018

Complete change of the protein folding transition state upon circular permutation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463891

26 October 2018

Probing the topology of the glycine receptor by chemical modification coupled to mass spectrometry

1 reference

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26 October 2018

Conformational plasticity in folding of the split beta-alpha-beta protein S6: evidence for burst-phase disruption of the native state

1 reference

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26 October 2018

Solvent effects on the reaction coordinate of the hydrolysis of phosphates and sulfates: application of Hammond and anti-Hammond postulates to understand hydrolysis in solution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463891

26 October 2018

Allosteric transitions of the acetylcholine receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1463891

26 October 2018

The Structure of the Transition State for Folding of Chymotrypsin Inhibitor 2 Analysed by Protein Engineering Methods: Evidence for a Nucleation-condensation Mechanism for Protein Folding

1 reference

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9 December 2018

High-energy channeling in protein folding

1 reference

https://pubmed.ncbi.nlm.nih.gov/14674774

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Movement of the position of the transition state in protein folding

1 reference

https://pubmed.ncbi.nlm.nih.gov/14674774

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exploring the energy surface of protein folding by structure-reactivity relationships and engineered proteins: observation of Hammond behavior for the gross structure of the transition state and anti-Hammond behavior for structural elements for unfo

1 reference

https://pubmed.ncbi.nlm.nih.gov/14674774

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microsecond protein folding through a compact transition state

1 reference

https://pubmed.ncbi.nlm.nih.gov/14674774

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Movement of the intermediate and rate determining transition state of barnase on the energy landscape with changing temperature

1 reference

https://pubmed.ncbi.nlm.nih.gov/14674774

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The changing nature of the protein folding transition state: implications for the shape of the free-energy profile for folding

1 reference

https://pubmed.ncbi.nlm.nih.gov/14674774

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Voltage dependence of mouse acetylcholine receptor gating: different charge movements in di-, mono- and unliganded receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/14674774

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/BI0354334

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

ResearchGate publication ID

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