(Q34498199)

2 August 2017

title

Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions (English)

1 reference

2 August 2017

Juli Feigon

1 reference

2 August 2017

Jiansen Jiang

1 reference

2 August 2017

Henry Chan

1 reference

2 August 2017

Darian D Cash

1 reference

2 August 2017

Edward J Miracco

1 reference

2 August 2017

Rachel R Ogorzalek Loo

1 reference

2 August 2017

Heather E Upton

1 reference

2 August 2017

Duilio Cascio

1 reference

2 August 2017

Reid O'Brien Johnson

1 reference

2 August 2017

Kathleen Collins

1 reference

2 August 2017

Joseph A Loo

1 reference

2 August 2017

Z Hong Zhou

1 reference

2 August 2017

language of work or name

English

0 references

publication date

15 October 2015

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2 August 2017

1 reference

2 August 2017

volume

350

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2 August 2017

issue

6260

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2 August 2017

page(s)

aab4070

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Identification of human TERT elements necessary for telomerase recruitment to telomeres

2 August 2017

cites work

1 reference

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Direct single-stranded DNA binding by Teb1 mediates the recruitment of Tetrahymena thermophila telomerase to telomeres

7 July 2018

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Genetic and molecular identification of three human TPP1 functions in telomerase action: recruitment, activation, and homeostasis set point regulation

7 July 2018

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7 July 2018

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Human telomerase specialization for repeat synthesis by unique handling of primer-template duplex

7 July 2018

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7 July 2018

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Structure of Est3 reveals a bimodal surface with differential roles in telomere replication

7 July 2018

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7 July 2018

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Tetrahymena telomerase holoenzyme assembly, activation, and inhibition by domains of the p50 central hub

7 July 2018

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7 July 2018

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CST for the grand finale of telomere replication.

7 July 2018

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Structure of the Human Telomeric Stn1-Ten1 Capping Complex

7 July 2018

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Pyrimidine motif triple helix in the Kluyveromyces lactis telomerase RNA pseudoknot is essential for function in vivo

7 July 2018

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Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM.

7 July 2018

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Finding the end: recruitment of telomerase to telomeres

7 July 2018

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A popular engagement at the ends

7 July 2018

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Human CST has independent functions during telomere duplex replication and C-strand fill-in

7 July 2018

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The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity

7 July 2018

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RELION: implementation of a Bayesian approach to cryo-EM structure determination

7 July 2018

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7 July 2018

The telomere syndromes

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The structure and function of replication protein A in DNA replication

7 July 2018

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Specificity requirements for human telomere protein interaction with telomerase holoenzyme

7 July 2018

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Everything you ever wanted to know about Saccharomyces cerevisiae telomeres: beginning to end.

7 July 2018

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Biogenesis of telomerase ribonucleoproteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

TPP1 OB-fold domain controls telomere maintenance by recruiting telomerase to chromosome ends

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

The human CST complex is a terminator of telomerase activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

Telomeric 3' overhangs derive from resection by Exo1 and Apollo and fill-in by POT1b-associated CST.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

Towards automated crystallographic structure refinement with phenix.refine

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

Roles of telomerase reverse transcriptase N-terminal domain in assembly and activity of Tetrahymena telomerase holoenzyme

7 July 2018

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Transcriptome analysis of the model protozoan, Tetrahymena thermophila, using Deep RNA sequencing

7 July 2018

1 reference

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Telomerase and telomere-associated proteins: structural insights into mechanism and evolution

7 July 2018

1 reference

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Structural basis for Tetrahymena telomerase processivity factor Teb1 binding to single-stranded telomeric-repeat DNA

7 July 2018

1 reference

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RNA-protein binding interface in the telomerase ribonucleoprotein

7 July 2018

1 reference

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It all comes together at the ends: telomerase structure, function, and biogenesis

7 July 2018

1 reference

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RNA/DNA hybrid binding affinity determines telomerase template-translocation efficiency

7 July 2018

1 reference

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Maintaining the end: Roles of telomere proteins in end-protection, telomere replication and length regulation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

The Pot1a-associated proteins Tpt1 and Pat1 coordinate telomere protection and length regulation in Tetrahymena.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

Stimulation of yeast telomerase activity by the ever shorter telomere 3 (Est3) subunit is dependent on direct interaction with the catalytic protein Est2.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

Functional importance of telomerase pseudoknot revealed by single-molecule analysis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

Tetrahymena telomerase protein p65 induces conformational changes throughout telomerase RNA (TER) and rescues telomerase reverse transcriptase and TER assembly mutants

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

Evolution of CST function in telomere maintenance

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

Telomerase: an RNP enzyme synthesizes DNA.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

Multiple mechanisms for elongation processivity within the reconstituted tetrahymena telomerase holoenzyme

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

Structural basis for telomerase catalytic subunit TERT binding to RNA template and telomeric DNA

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

A synergistic approach to protein crystallization: combination of a fixed-arm carrier with surface entropy reduction.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

Integration, scaling, space-group assignment and post-refinement

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

A novel motif in telomerase reverse transcriptase regulates telomere repeat addition rate and processivity.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

Stn1-Ten1 is an Rpa2-Rpa3-like complex at telomeres

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

Telomeres and telomerase in cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

Phasercrystallographic software

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

DoG Picker and TiltPicker: software tools to facilitate particle selection in single particle electron microscopy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

Solution structure and dynamics of the wild-type pseudoknot of human telomerase RNA

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

Structure of the Tribolium castaneum telomerase catalytic subunit TERT

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

Mutation in TERT separates processivity from anchor-site function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

Triple-helix structure in telomerase RNA contributes to catalysis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

The Jpred 3 secondary structure prediction server

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

Structure of the RNA-binding domain of telomerase: implications for RNA recognition and binding

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

Stepwise protein-mediated RNA folding directs assembly of telomerase ribonucleoprotein

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

The POT1-TPP1 telomere complex is a telomerase processivity factor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

TPP1 is a homologue of ciliate TEBP-beta and interacts with POT1 to recruit telomerase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

Tetrahymena POT1a regulates telomere length and prevents activation of a cell cycle checkpoint

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

Telomeres and telomerase: the path from maize, Tetrahymena and yeast to human cancer and aging

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

Bsoft: image processing and molecular modeling for electron microscopy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

Structure and function of telomerase RNA

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

A novel RNA binding domain in tetrahymena telomerase p65 initiates hierarchical assembly of telomerase holoenzyme

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

Crystal structure of the essential N-terminal domain of telomerase reverse transcriptase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

Automated molecular microscopy: the new Leginon system

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

Structure of the human telomerase RNA pseudoknot reveals conserved tertiary interactions essential for function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

Coot: model-building tools for molecular graphics

7 July 2018

1 reference

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LNA (locked nucleic acid): high-affinity targeting of complementary RNA and DNA.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

UCSF Chimera--a visualization system for exploratory research and analysis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

Holoenzyme proteins required for the physiological assembly and activity of telomerase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

A Conserved Telomerase Motif within the Catalytic Domain of Telomerase Reverse Transcriptase Is Specifically Required for Repeat Addition Processivity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

Accurate determination of local defocus and specimen tilt in electron microscopy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

Structure of the RPA trimerization core and its role in the multistep DNA-binding mechanism of RPA

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

A critical stem-loop structure in the CR4-CR5 domain of mammalian telomerase RNA.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

EMAN: semiautomated software for high-resolution single-particle reconstructions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4687456

The architecture of Tetrahymena telomerase holoenzyme

7 July 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAB4070

Structural study of elements of Tetrahymena telomerase RNA stem-loop IV domain important for function

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAB4070

Structure of the Tetrahymena thermophila telomerase RNA helix II template boundary element

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAB4070

Structural Analysis Reveals Conformational Plasticity in the Recognition of RNA 3′ Ends by the Human La Protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAB4070

Structure and conformational change of a replication protein A heterotrimer bound to ssDNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAB4070

Multi-resolution contour-based fitting of macromolecular structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAB4070

21 January 2018

Identifiers

DOI

10.1126/SCIENCE.AAB4070

1 reference

2 August 2017

1 reference

2 August 2017

1 reference