(Q34243592)

31 July 2017

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title

The Tec family of cytoplasmic tyrosine kinases: mammalian Btk, Bmx, Itk, Tec, Txk and homologs in other species (English)

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31 July 2017

Smith CI

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31 July 2017

Islam TC

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31 July 2017

Mattsson PT

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31 July 2017

Mohamed AJ

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31 July 2017

Nore BF

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31 July 2017

Vihinen M

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31 July 2017

language of work or name

English

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publication date

1 May 2001

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31 July 2017

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31 July 2017

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31 July 2017

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31 July 2017

page(s)

436-446

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The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases

31 July 2017

cites work

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Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia

21 January 2018

1 reference

Structure and expression of novel protein-tyrosine kinases, Emb and Emt, in hematopoietic cells

21 January 2018

1 reference

A tyrosine kinase profile of prostate carcinoma

21 January 2018

1 reference

itk, a T-cell-specific tyrosine kinase gene inducible by interleukin 2

21 January 2018

1 reference

Developmental regulation of a murine T-cell-specific tyrosine kinase gene, Tsk

21 January 2018

1 reference

TXK, a novel human tyrosine kinase expressed in T cells shares sequence identity with Tec family kinases and maps to 4p12

21 January 2018

1 reference

Identification of Rlk, a novel protein tyrosine kinase with predominant expression in the T cell lineage

21 January 2018

1 reference

The Tec29 tyrosine kinase is required during Drosophila embryogenesis and interacts with Src64 in ring canal development

21 January 2018

1 reference

SRC64 regulates the localization of a Tec-family kinase required for Drosophila ring canal growth

21 January 2018

1 reference

The Drosophila Bruton's tyrosine kinase (Btk) homolog is required for adult survival and male genital formation

21 January 2018

1 reference

Identification and characterization of a homologue of Bruton's tyrosine kinase, a Tec kinase involved in B-cell development, in a modern representative of a phylogenetically ancient vertebrate

21 January 2018

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Tec-family non-receptor tyrosine kinase expressed in zebrafish kidney

21 January 2018

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A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-gamma 2.

21 January 2018

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The protein tyrosine kinases of the sea urchin Anthocidaris crassispina

21 January 2018

1 reference

rlk/TXK encodes two forms of a novel cysteine string tyrosine kinase activated by Src family kinases

21 January 2018

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Mutation of unique region of Bruton's tyrosine kinase in immunodeficient XID mice

21 January 2018

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X-linked agammaglobulinemia and other immunoglobulin deficiencies

21 January 2018

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Tec homology (TH) adjacent to the PH domain.

21 January 2018

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Missense mutations affecting a conserved cysteine pair in the TH domain of Btk

21 January 2018

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Structure of the PH domain and Btk motif from Bruton's tyrosine kinase: molecular explanations for X-linked agammaglobulinaemia

21 January 2018

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Comparative genomics of the eukaryotes

21 January 2018

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Splice variants of the mouse Tec gene are differentially expressed in vivo

21 January 2018

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Deletion within the Src homology domain 3 of Bruton's tyrosine kinase resulting in X-linked agammaglobulinemia (XLA)

21 January 2018

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Structure of the PH domain from Bruton's tyrosine kinase in complex with inositol 1,3,4,5-tetrakisphosphate

21 January 2018

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Regulatory intramolecular association in a tyrosine kinase of the Tec family

21 January 2018

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Solution structure of the SH3 domain from Bruton's tyrosine kinase

21 January 2018

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Six X-Linked Agammaglobulinemia-Causing Missense Mutations in the Src Homology 2 Domain of Bruton's Tyrosine Kinase: Phosphotyrosine-Binding and Circular Dichroism Analysis

21 January 2018

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Thermal unfolding of small proteins with SH3 domain folding pattern.

21 January 2018

1 reference

Activation of BTK by a phosphorylation mechanism initiated by SRC family kinases

21 January 2018

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Regulation of Btk function by a major autophosphorylation site within the SH3 domain

21 January 2018

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The pleckstrin homology domain of Bruton tyrosine kinase interacts with protein kinase C

21 January 2018

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The protein product of the c-cbl protooncogene is phosphorylated after B cell receptor stimulation and binds the SH3 domain of Bruton's tyrosine kinase

21 January 2018

1 reference

Identification of Itk/Tsk Src homology 3 domain ligands

21 January 2018

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Direct stimulation of Bruton's tyrosine kinase by Gq-protein α-subunit

21 January 2018

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BAP-135, a target for Bruton's tyrosine kinase in response to B cell receptor engagement

21 January 2018

1 reference

Identification and characterization of a novel SH3-domain binding protein, Sab, which preferentially associates with Bruton's tyrosine kinase (BtK)

21 January 2018

1 reference

RIBP, a novel Rlk/Txk- and itk-binding adaptor protein that regulates T cell activation

21 January 2018

1 reference

Bruton's tyrosine kinase as an inhibitor of the Fas/CD95 death-inducing signaling complex.

21 January 2018

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The role of Tec protein-tyrosine kinase in T cell signaling

21 January 2018

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Pleckstrin homology domains interact with filamentous actin

21 January 2018

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Biochemical interactions integrating Itk with the T cell receptor-initiated signaling cascade

21 January 2018

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Etk, a Btk family tyrosine kinase, mediates cellular transformation by linking Src to STAT3 activation

21 January 2018

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Resting lymphocyte kinase (Rlk/Txk) targets lymphoid adaptor SLP-76 in the cooperative activation of interleukin-2 transcription in T-cells

21 January 2018

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Src-induced activation of inducible T cell kinase (ITK) requires phosphatidylinositol 3-kinase activity and the Pleckstrin homology domain of inducible T cell kinase

21 January 2018

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Etk/Bmx, a tyrosine kinase with a pleckstrin-homology domain, is an effector of phosphatidylinositol 3'-kinase and is involved in interleukin 6-induced neuroendocrine differentiation of prostate cancer cells

21 January 2018

1 reference

Tec family of protein-tyrosine kinases: an overview of their structure and function

21 January 2018

1 reference

BLNK: connecting Syk and Btk to calcium signals

21 January 2018

1 reference

X-linked agammaglobulinemia (XLA): a genetic tyrosine kinase (Btk) disease

21 January 2018

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Nucleocytoplasmic shuttling of Bruton's tyrosine kinase

21 January 2018

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T cell receptor-initiated calcium release is uncoupled from capacitative calcium entry in Itk-deficient T cells

21 January 2018

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Impaired NFATc translocation and failure of Th2 development in Itk-deficient CD4+ T cells

21 January 2018

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Tec/Bmx non-receptor tyrosine kinases are involved in regulation of Rho and serum response factor by Galpha12/13

21 January 2018

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Transgene expression of bcl-xL permits anti-immunoglobulin (Ig)-induced proliferation in xid B cells

21 January 2018

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BTK as a mediator of radiation-induced apoptosis in DT-40 lymphoma B cells

21 January 2018

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Bruton's tyrosine kinase regulates apoptosis and JNK/SAPK kinase activity

21 January 2018

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The cellular phenotype conditions Btk for cell survival or apoptosis signaling.

21 January 2018

1 reference

Activation of Bruton's tyrosine kinase (BTK) by a point mutation in its pleckstrin homology (PH) domain

21 January 2018

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Severe B cell deficiency and disrupted splenic architecture in transgenic mice expressing the E41K mutated form of Bruton's tyrosine kinase

21 January 2018

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The Bmx tyrosine kinase is activated by IL-3 and G-CSF in a PI-3K dependent manner

21 January 2018

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Requirement for Tec kinases Rlk and Itk in T cell receptor signaling and immunity

21 January 2018

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Bmx Tyrosine Kinase Is Specifically Expressed in the Endocardium and the Endothelium of Large Arteries

21 January 2018

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Reconstitution of Btk signaling by the atypical tec family tyrosine kinases Bmx and Txk.

21 January 2018

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Regulation of Btk by Src family tyrosine kinases

21 January 2018

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Defective B cell development and function in Btk-deficient mice

21 January 2018

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Severe B cell deficiency in mice lacking the tec kinase family members Tec and Btk.

21 January 2018

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Altered T cell receptor signaling and disrupted T cell development in mice lacking Itk.

21 January 2018

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A role for the Tec family tyrosine kinase Txk in T cell activation and thymocyte selection

21 January 2018

1 reference

The protein kinases of Caenorhabditis elegans: a model for signal transduction in multicellular organisms

21 January 2018

1 reference

Guidelines for human gene nomenclature (1997). HUGO Nomenclature Committee

21 January 2018

1 reference

Animal evolution. The end of the intermediate taxa?

21 January 2018

1 reference

The Sequence of the Human Genome

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/BIES.1062

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31 July 2017

1 reference