(Q41700451)

7 October 2017

title

Impaired NFATc translocation and failure of Th2 development in Itk-deficient CD4+ T cells (English)

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7 October 2017

Fowell DJ

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7 October 2017

Shinkai K

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7 October 2017

Liao XC

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7 October 2017

Beebe AM

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7 October 2017

Coffman RL

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7 October 2017

Littman DR

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7 October 2017

Locksley RM

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7 October 2017

language of work or name

English

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publication date

1 October 1999

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7 October 2017

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7 October 2017

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7 October 2017

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7 October 2017

page(s)

399-409

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Functional diversity of helper T lymphocytes

7 October 2017

cites work

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7 January 2021

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7 January 2021

Proline-rich sequences that bind to Src homology 3 domains with individual specificities

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7 January 2021

Src-induced activation of inducible T cell kinase (ITK) requires phosphatidylinositol 3-kinase activity and the Pleckstrin homology domain of inducible T cell kinase

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7 January 2021

CBP/p300 Integrates Raf/Rac-Signaling Pathways in the Transcriptional Induction of NF-ATc during T Cell Activation

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7 January 2021

Antiviral immune responses in Itk-deficient mice.

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7 January 2021

Serial backcross mapping of multiple loci associated with resistance to Leishmania major in mice

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7 January 2021

Calcium - a life and death signal

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7 January 2021

Helper T cell differentiation is controlled by the cell cycle

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7 January 2021

Independent and epigenetic regulation of the interleukin-4 alleles in CD4+ T cells

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7 January 2021

Genetic regulation of commitment to interleukin 4 production by a CD4(+) T cell-intrinsic mechanism

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7 January 2021

Initiation of signal transduction through the T cell receptor requires the multivalent engagement of peptide/MHC ligands [corrected]

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7 January 2021

Beta 2-microglobulin-dependent NK1.1+ T cells are not essential for T helper cell 2 immune responses

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7 January 2021

Limited role of CD28-mediated signals in T helper subset differentiation

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7 January 2021

A role for CD4 in peripheral T cell differentiation

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7 January 2021

Drosophila ring canal growth requires Src and Tec kinases

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7 January 2021

Generic signals and specific outcomes: signaling through Ca2+, calcineurin, and NF-AT

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7 January 2021

Differential activation of transcription factors induced by Ca2+ response amplitude and duration

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7 January 2021

Calcium oscillations increase the efficiency and specificity of gene expression

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7 January 2021

Btk/Tec kinases regulate sustained increases in intracellular Ca2+ following B-cell receptor activation

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7 January 2021

Leishmania major infection of inbred mice: unmasking genetic determinants of infectious diseases

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7 January 2021

Impaired Th2 subset development in the absence of CD4.

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7 January 2021

Nuclear factor of activated T cells (NFAT)-dependent transactivation regulated by the coactivators p300/CREB-binding protein (CBP)

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7 January 2021

Cell division regulates the T cell cytokine repertoire, revealing a mechanism underlying immune class regulation

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7 January 2021

Genetic mapping of a murine locus controlling development of T helper 1/T helper 2 type responses

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7 January 2021

Involvement of Bruton's tyrosine kinase in FcepsilonRI-dependent mast cell degranulation and cytokine production

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7 January 2021

Lck phosphorylates the activation loop tyrosine of the Itk kinase domain and activates Itk kinase activity

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7 January 2021

T cell genetic background determines default T helper phenotype development in vitro

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7 January 2021

Resistance to Leishmania major induced by tolerance to a single antigen

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7 January 2021

Down-regulation of IL-4 gene transcription and control of Th2 cell differentiation by a mechanism involving NFAT1

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7 January 2021

IL-4 Rapidly Produced by Vβ4 Vα8 CD4+ T Cells Instructs Th2 Development and Susceptibility to Leishmania major in BALB/c Mice

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7 January 2021

Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells

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7 January 2021

Cell-permeant caged InsP3 ester shows that Ca2+ spike frequency can optimize gene expression

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7 January 2021

Altered T cell receptor signaling and disrupted T cell development in mice lacking Itk.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980115-6

7 January 2021

Itk negatively regulates induction of T cell proliferation by CD28 costimulation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980115-6

7 January 2021

Itk and Fyn make independent contributions to T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980115-6

7 January 2021

T cell receptor-initiated calcium release is uncoupled from capacitative calcium entry in Itk-deficient T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980115-6

7 January 2021

Helper T cells without CD4: control of leishmaniasis in CD4-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980115-6

7 January 2021

Cytokines induce the development of functionally heterogeneous T helper cell subsets

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7 January 2021

Lymphoid development in mice congenitally lacking T cell receptor alpha beta-expressing cells

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7 January 2021

Altered ligands reveal limited plasticity in the T cell response to a pathogenic epitope

1 reference

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7 January 2021

Delayed lymphoid repopulation with defects in IL-4-driven responses produced by inactivation of NF-ATc

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980115-6

7 January 2021

Inhibitory function of two NFAT family members in lymphoid homeostasis and Th2 development.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980115-6

7 January 2021

Activation of BTK by a phosphorylation mechanism initiated by SRC family kinases

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980115-6

7 January 2021

Ligand-specific oligomerization of T-cell receptor molecules

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980115-6

7 January 2021

The regulation of immunity to Leishmania major

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980115-6

7 January 2021

Constructing polycompetitor cDNAs for quantitative PCR.

1 reference

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7 January 2021

Leishmania promastigotes evade interleukin 12 (IL-12) induction by macrophages and stimulate a broad range of cytokines from CD4+ T cells during initiation of infection

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980115-6

7 January 2021

Btk dosage determines sensitivity to B cell antigen receptor cross-linking

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980115-6

7 January 2021

Independent and opposing roles for Btk and lyn in B and myeloid signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980115-6

7 January 2021

Requirement for Tec kinases Rlk and Itk in T cell receptor signaling and immunity

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980115-6

7 January 2021

PtdIns-3,4,5-P3: a regulatory nexus between tyrosine kinases and sustained calcium signals

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980115-6

7 January 2021

Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980115-6

7 January 2021

Local delivery of interleukin 4 by retrovirus-transduced T lymphocytes ameliorates experimental autoimmune encephalomyelitis.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980115-6

7 January 2021

Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980115-6

7 January 2021

A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-gamma 2.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980115-6

7 January 2021

Th2-specific DNase I-hypersensitive sites in the murine IL-13 and IL-4 intergenic region.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980115-6

7 January 2021

Rapid shuttling of NF-AT in discrimination of Ca2+ signals and immunosuppression

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980115-6

7 January 2021

IL-13, IL-4Ralpha, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980115-6

7 January 2021

Reconstitution of C.B-17 scid mice with BALB/c T cells initiates a T helper type-1 response and renders them capable of healing Leishmania major infection

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980115-6

7 January 2021

Requirement for p56(lck) tyrosine kinase activation in Th subset differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980115-6

7 January 2021

The role of Tec protein-tyrosine kinase in T cell signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980115-6

7 January 2021

The transcription factor NF-ATc1 regulates lymphocyte proliferation and Th2 cytokine production

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980115-6

7 January 2021

10.1016/S1074-7613(00)80115-6

Identifiers

DOI

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7 October 2017

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