(Q34021737)

30 July 2017

title

Constitutive non-canonical NFkappaB signaling in pancreatic cancer cells (English)

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30 July 2017

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Michael J May

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Catherine E Wharry

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30 July 2017

Kathleen M Haines

series ordinal

1 reference

30 July 2017

Richard G Carroll

series ordinal

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30 July 2017

publication date

8 August 2009

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Cancer Biology and Therapy

30 July 2017

published in

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30 July 2017

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30 July 2017

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30 July 2017

page(s)

1567-1576

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CXCL13 production by an established lymph node stromal cell line via lymphotoxin-beta receptor engagement involves the cooperation of multiple signaling pathways.

30 July 2017

cites work

1 reference

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Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK.

5 July 2018

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Maintenance of constitutive IkappaB kinase activity by glycogen synthase kinase-3alpha/beta in pancreatic cancer

5 July 2018

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SN52, a novel nuclear factor-kappaB inhibitor, blocks nuclear import of RelB:p52 dimer and sensitizes prostate cancer cells to ionizing radiation

5 July 2018

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The role of NF-kappaB in lymphoid malignancies

5 July 2018

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Lymphotoxin-alpha 1 beta 2 and LIGHT induce classical and noncanonical NF-kappa B-dependent proinflammatory gene expression in vascular endothelial cells

5 July 2018

1 reference

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Control of canonical NF-kappaB activation through the NIK-IKK complex pathway

5 July 2018

1 reference

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Shared principles in NF-kappaB signaling

5 July 2018

1 reference

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Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma.

5 July 2018

1 reference

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Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma

5 July 2018

1 reference

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NF-kappaB2 processing and p52 nuclear accumulation after androgenic stimulation of LNCaP prostate cancer cells

5 July 2018

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Inhibitors of NF-kappaB signaling: 785 and counting

5 July 2018

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Nuclear factor-kappaB and inhibitor of kappaB kinase pathways in oncogenic initiation and progression

5 July 2018

1 reference

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Regulation and function of IKK and IKK-related kinases

5 July 2018

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Differential expression and activation of NF-kappaB family proteins during oral carcinogenesis: Role of high risk human papillomavirus infection

5 July 2018

1 reference

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BAFF and APRIL support chronic lymphocytic leukemia B-cell survival through activation of the canonical NF-kappaB pathway

5 July 2018

1 reference

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IKKalpha controls p52/RelB at the skp2 gene promoter to regulate G1- to S-phase progression.

5 July 2018

1 reference

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Role of BAFF and APRIL in human B-cell chronic lymphocytic leukaemia.

5 July 2018

1 reference

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Multiple initial culture conditions enhance the establishment of cell lines from primary ovarian cancer specimens

5 July 2018

1 reference

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Nuclear factor-kappaB in cancer development and progression

5 July 2018

1 reference

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NF-kappaB and IKK as therapeutic targets in cancer

5 July 2018

1 reference

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Nuclear localisation of nuclear factor-kappaB transcription factors in prostate cancer: an immunohistochemical study

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910422

Glycogen synthase kinase-3beta participates in nuclear factor kappaB-mediated gene transcription and cell survival in pancreatic cancer cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910422

Increased survival, proliferation, and migration in metastatic human pancreatic tumor cells expressing functional CXCR4.

5 July 2018

1 reference

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Type I collagen promotes the malignant phenotype of pancreatic ductal adenocarcinoma.

5 July 2018

1 reference

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A comprehensive in vitro characterization of pancreatic ductal carcinoma cell line biological behavior and its correlation with the structural and genetic profile

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910422

The two NF-kappaB activation pathways and their role in innate and adaptive immunity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910422

Increased expression of NF-kappa B subunits in human pancreatic cancer cells

5 July 2018

1 reference

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The IKK NF-kappa B system: a treasure trove for drug development

5 July 2018

1 reference

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Identification of an autoregulatory feedback pathway involving interleukin-1alpha in induction of constitutive NF-kappaB activation in pancreatic cancer cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910422

NF-kappaB in pancreatic cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910422

Inhibition of constitutive NF-kappa B activity by I kappa B alpha M suppresses tumorigenesis

5 July 2018

1 reference

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Function of nuclear factor kappaB in pancreatic cancer metastasis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910422

The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910422

CD40 regulates the processing of NF-kappaB2 p100 to p52

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910422

Selective targeting of the nuclear factor-kappaB pathway enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated pancreatic cancer cell death

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910422

Inflammation and the development of pancreatic cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910422

Stromal-derived factor-1 in human tumors recruits and alters the function of plasmacytoid precursor dendritic cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910422

Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910422

Expression of stromal cell-derived factor 1 and CXCR4 ligand receptor system in pancreatic cancer: a possible role for tumor progression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910422

Regulation of NF-kappaB activity by I kappaB-related proteins in adenocarcinoma cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910422

A cytokine-responsive IκB kinase that activates the transcription factor NF-κB

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910422

Highly-expressed p100/p52 (NFKB2) sequesters other NF-kappa B-related proteins in the cytoplasm of human breast cancer cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910422

Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910422

CXCL12 and vascular endothelial growth factor synergistically induce neoangiogenesis in human ovarian cancers.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910422

Lymphoma B cells evade apoptosis through the TNF family members BAFF/BLyS and APRIL.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910422

NF-kappaB activity blockade impairs the angiogenic potential of human pancreatic cancer cells

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910422

Mitogenic and antiapoptotic role of constitutive NF-kappaB/Rel activity in pancreatic cancer

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910422

Expression of B-cell-attracting chemokine 1 (CXCL13) by malignant lymphocytes and vascular endothelium in primary central nervous system lymphoma

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910422

BAFF-induced NEMO-independent processing of NF-kappa B2 in maturing B cells.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910422

RelB/p50 Dimers Are Differentially Regulated by Tumor Necrosis Factor-α and Lymphotoxin-β Receptor Activation

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910422

Differential expression of chemokines, chemokine receptors, cytokines and cytokine receptors in diffuse large B cell malignant lymphoma

10 December 2018

1 reference

12 December 2020

The nuclear factor-kappa B RelA transcription factor is constitutively activated in human pancreatic adenocarcinoma cells

1 reference

12 December 2020

Selective activation of NF-kappa B subunits in human breast cancer: potential roles for NF-kappa B2/p52 and for Bcl-3

1 reference

12 December 2020

Nuclear factor-kappaB maintains TRAIL resistance in human pancreatic cancer cells

1 reference

12 December 2020

Identifiers

DOI

10.4161/CBT.8.16.8961

1 reference

30 July 2017

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30 July 2017

1 reference