(Q30574939)

21 August 2017

Safety, pharmacokinetics, and preliminary assessment of efficacy of mecasermin (recombinant human IGF-1) for the treatment of Rett syndrome (English)

1 reference

21 August 2017

1 reference

0 references

Ingrid A Holm

0 references

Walter E Kaufmann

1 reference

21 August 2017

Omar S Khwaja

1 reference

21 August 2017

Eugenia Ho

1 reference

21 August 2017

Katherine V Barnes

1 reference

21 August 2017

Heather M O'Leary

1 reference

21 August 2017

Luis M Pereira

1 reference

21 August 2017

Yaron Finkelstein

1 reference

21 August 2017

Charles A Nelson

1 reference

21 August 2017

Vanessa Vogel-Farley

1 reference

21 August 2017

Geneva DeGregorio

1 reference

21 August 2017

Umakanth Khatwa

1 reference

21 August 2017

Kush Kapur

1 reference

21 August 2017

Mark E Alexander

1 reference

21 August 2017

Deirdre M Finnegan

1 reference

21 August 2017

Nicole G Cantwell

1 reference

21 August 2017

Alexandra C Walco

1 reference

21 August 2017

Leonard Rappaport

1 reference

21 August 2017

Matt Gregas

1 reference

21 August 2017

Raina N Fichorova

1 reference

21 August 2017

Michael W Shannon

1 reference

21 August 2017

Mriganka Sur

1 reference

21 August 2017

language of work or name

English

0 references

publication date

12 March 2014

1 reference

Proceedings of the National Academy of Sciences of the United States of America

21 August 2017

1 reference

21 August 2017

111

1 reference

21 August 2017

1 reference

21 August 2017

4596-4601

1 reference

Functional recovery with recombinant human IGF1 treatment in a mouse model of Rett Syndrome

21 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970488

Insulin-like growth factor-1 and its derivatives: potential pharmaceutical application for treating neurological conditions

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970488

Insulinotropic treatments exacerbate metabolic syndrome in mice lacking MeCP2 function

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970488

Changing the perspective on early development of Rett syndrome

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970488

Reversal of disease-related pathologies in the fragile X mouse model by selective activation of GABAB receptors with arbaclofen.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970488

IGF1 as a Potential Treatment for Rett Syndrome: Safety Assessment in Six Rett Patients

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970488

Neurodevelopmental effects of insulin-like growth factor signaling

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970488

The insulin-like growth factors and growth disorders of childhood

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970488

Morphological and functional reversal of phenotypes in a mouse model of Rett syndrome

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970488

The short-time structural plasticity of dendritic spines is altered in a model of Rett syndrome

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970488

Translational research: Rett syndrome and tuberous sclerosis complex

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970488

Peptide mimetics of neurotrophins and their receptors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970488

Clinical assessment of DSM-IV anxiety disorders in fragile X syndrome: prevalence and characterization

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970488

Normal ranges of heart rate and respiratory rate in children from birth to 18 years of age: a systematic review of observational studies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970488

Epigenetic modification of the FMR1 gene in fragile X syndrome is associated with differential response to the mGluR5 antagonist AFQ056.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970488

Rett syndrome: revised diagnostic criteria and nomenclature

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970488

Rett syndrome diagnostic criteria: lessons from the Natural History Study

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970488

A wearable sensor for unobtrusive, long-term assessment of electrodermal activity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970488

Partial reversal of Rett Syndrome-like symptoms in MeCP2 mutant mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970488

Mecasermin (recombinant human insulin-like growth factor I).

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970488

Correction of fragile X syndrome in mice.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970488

Reversal of neurological defects in a mouse model of Rett syndrome

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970488

Depression, anxiety, and resting frontal EEG asymmetry: a meta-analytic review

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970488

Breathing generation and potential pharmacotherapeutic approaches to central respiratory disorders

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970488

MeCP2 expression and function during brain development: implications for Rett syndrome's pathogenesis and clinical evolution

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970488

Reliability and validity of an assessment instrument for anxiety, depression, and mood among individuals with mental retardation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970488

Clinical trials and treatment prospects

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970488

Clinical manifestations and stages of Rett syndrome

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970488

Validation of a new respiratory inductive plethysmograph

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970488

Early childhood predictors of adult anxiety disorders

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970488

Recent insights into hyperventilation from the study of Rett syndrome.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970488

Methyl CpG-binding protein 2 (a mutation of which causes Rett syndrome) directly regulates insulin-like growth factor binding protein 3 in mouse and human brains

20 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1311141111

Dexmedetomidine pharmacodynamics: part I: crossover comparison of the respiratory effects of dexmedetomidine and remifentanil in healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1311141111

The Rett Syndrome Behaviour Questionnaire (RSBQ): refining the behavioural phenotype of Rett syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1311141111

Social impairments in Rett syndrome: characteristics and relationship with clinical severity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1311141111

Insulin-like growth factor 1 (IGF1) and its active peptide (1-3)IGF1 enhance the expression of synaptic markers in neuronal circuits through different cellular mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1311141111

Pubertal trajectory in females with Rett syndrome: a population-based study

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1311141111

Effects of fluoxetine treatment on striatal dopamine transporter binding and cerebrospinal fluid insulin-like growth factor-1 in children with autism

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1311141111

Insulin-like growth factor-1 is associated with cognitive outcome in infantile spasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1311141111

Disturbances in cardiorespiratory function during day and night in Rett syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1311141111

The development of visual- and auditory processing in Rett syndrome: an ERP study

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1311141111

Report of the committee on methods of clinical examination in electroencephalography

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1311141111

EEG asymmetry, power, and temperament in children

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1311141111

A comparison of the electroencephalogram between institutionalized and community children in Romania.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1311141111

Report of the first case of precocious puberty in Rett syndrome

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970488

Pharmacokinetics of recombinant human insulin-like growth factor I given subcutaneously to healthy volunteers and to patients with growth hormone receptor deficiency

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24623853

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Effects of STX209 (arbaclofen) on neurobehavioral function in children and adults with fragile X syndrome: a randomized, controlled, phase 2 trial

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24623853

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1311141111

1 reference

21 August 2017

0 references

1 reference

21 August 2017

PubMed publication ID

24623853

1 reference