(Q30497487)

30 September 2017

Inositol hexakisphosphate kinase-2 acts as an effector of the vertebrate Hedgehog pathway (English)

1 reference

Inositol hexakisphosphate kinase 2a

30 September 2017

1 reference

GOA release 2020-03-11

signal transduction

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20980661

11 August 2024

Susan R Wente

1 reference

30 September 2017

Bhaskarjyoti Sarmah

1 reference

30 September 2017

language of work or name

English

0 references

publication date

27 October 2010

1 reference

full work available at URL

30 September 2017

http://www.pnas.org/content/107/46/19921.full.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20980661

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20980661/?tool=EBI

11 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20980661

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20980661/pdf/?tool=EBI

11 August 2024

file format

Portable Document Format

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20980661

https://europepmc.org/articles/PMC2993352

11 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20980661

https://europepmc.org/articles/PMC2993352?pdf=render

11 August 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20980661

https://doi.org/10.1073/pnas.1007256107

11 August 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20980661

Proceedings of the National Academy of Sciences of the United States of America

11 August 2024

published in

1 reference

30 September 2017

107

1 reference

30 September 2017

1 reference

30 September 2017

19921-19926

1 reference

Zebrafish inositol polyphosphate kinases: new effectors of cilia and developmental signaling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993352

Phosphoinositide signaling: new tools and insights.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993352

The hedgehog signaling pathway: where did it come from?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993352

Gene deletion of inositol hexakisphosphate kinase 2 predisposes to aerodigestive tract carcinoma

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993352

Characterization of a selective inhibitor of inositol hexakisphosphate kinases: use in defining biological roles and metabolic relationships of inositol pyrophosphates.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993352

Hedgehog signaling in development and cancer.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993352

Structural analysis and detection of biological inositol pyrophosphates reveal that the family of VIP/diphosphoinositol pentakisphosphate kinases are 1/3-kinases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993352

Hedgehog: functions and mechanisms

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993352

Multiple roles for lipids in the Hedgehog signalling pathway

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993352

Beta-arrestin-mediated localization of smoothened to the primary cilium

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993352

Gene deletion of inositol hexakisphosphate kinase 1 reveals inositol pyrophosphate regulation of insulin secretion, growth, and spermiogenesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993352

CNS-derived glia ensheath peripheral nerves and mediate motor root development

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993352

A role for the inositol kinase Ipk1 in ciliary beating and length maintenance

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993352

Requirement of inositol pyrophosphates for full exocytotic capacity in pancreatic beta cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993352

Inositol polyphosphates: a new frontier for regulating gene expression

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993352

A conserved family of enzymes that phosphorylate inositol hexakisphosphate

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993352

Regulation of nuclear processes by inositol polyphosphates

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993352

Inositol hexakisphosphate kinase-2, a physiologic mediator of cell death

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993352

Temporal perturbations in sonic hedgehog signaling elicit the spectrum of holoprosencephaly phenotypes.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993352

lockjaw encodes a zebrafish tfap2a required for early neural crest development.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993352

Cranial neural crest and the building of the vertebrate head

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993352

A defective response to Hedgehog signaling in disorders of cholesterol biosynthesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993352

Genetic analysis of zebrafish gli1 and gli2 reveals divergent requirements for gli genes in vertebrate development

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993352

Inositol pyrophosphates regulate endocytic trafficking

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993352

Small molecule modulation of Smoothened activity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993352

The winged-helix transcription factor Foxd3 suppresses interneuron differentiation and promotes neural crest cell fate

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993352

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993352

The inositol hexakisphosphate kinase family. Catalytic flexibility and function in yeast vacuole biogenesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993352

Arrestin function in G protein-coupled receptor endocytosis requires phosphoinositide binding

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993352

The teratogenic Veratrum alkaloid cyclopamine inhibits sonic hedgehog signal transduction.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993352

Notochord induction of zebrafish slow muscle mediated by Sonic hedgehog.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993352

Mutations affecting somite formation and patterning in the zebrafish, Danio rerio.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993352

A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993352

Combinatorial expression of three zebrafish genes related to distal-less: part of a homeobox gene code for the head.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993352

Diversity of expression of engrailed-like antigens in zebrafish

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993352

Inositol diphosphate signaling regulates telomere length

20 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1007256107

Inositol pyrophosphates mediate chemotaxis in Dictyostelium via pleckstrin homology domain-PtdIns(3,4,5)P3 interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1007256107

Hedgehog signaling is required for cranial neural crest morphogenesis and chondrogenesis at the midline in the zebrafish skull.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1007256107

Inositol polyphosphates regulate zebrafish left-right asymmetry

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1007256107

A pair of Sox: distinct and overlapping functions of zebrafish sox9 co-orthologs in craniofacial and pectoral fin development

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1007256107

Early Hedgehog signaling from neural to oral epithelium organizes anterior craniofacial development

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1007256107

Slow muscle regulates the pattern of trunk neural crest migration in zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1007256107

Transcriptional activation of hedgehog target genes in Drosophila is mediated directly by the cubitus interruptus protein, a member of the GLI family of zinc finger DNA-binding proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1007256107

Teratogen-mediated inhibition of target tissue response to Shh signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1007256107

Nonvisual arrestin oligomerization and cellular localization are regulated by inositol hexakisphosphate binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1007256107

Analysis of the zebrafish smoothened mutant reveals conserved and divergent functions of hedgehog activity.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993352

The zebrafish slow-muscle-omitted gene product is required for Hedgehog signal transduction and the development of slow muscle identity

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993352

Spatial regulation of a zebrafish patched homologue reflects the roles of sonic hedgehog and protein kinase A in neural tube and somite patterning.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993352

Specific pan-neural crest expression of zebrafish Crestin throughout embryonic development

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20980661

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1007256107

1 reference

release_6uvui6gocffohjnow773p45rja

30 September 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/6uvui6gocffohjnow773p45rja

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

30 September 2017

1 reference