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Regulation of microRNA biogenesis

scientific article (publication date: August 2014)

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Regulation of microRNA biogenesis (English)

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Minju Ha

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V Narry Kim

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August 2014

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Nature Reviews Molecular Cell Biology

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15

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8

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509-24

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Small silencing RNAs: an expanding universe

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Biology of PIWI-interacting RNAs: new insights into biogenesis and function inside and outside of germlines

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Gene silencing by microRNAs: contributions of translational repression and mRNA decay

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

MicroRNAs: target recognition and regulatory functions

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Most mammalian mRNAs are conserved targets of microRNAs

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

The microcosmos of cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

MicroRNAs in neuronal function and dysfunction

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Biogenesis of small RNAs in animals

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

The widespread regulation of microRNA biogenesis, function and decay

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Posttranscriptional regulation of microRNA biogenesis in animals

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Vive la différence: biogenesis and evolution of microRNAs in plants and animals

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Evolution and functional diversification of MIRNA genes

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Origin, biogenesis, and activity of plant microRNAs

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

RNA interference pathways in fungi: mechanisms and functions

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

miRBase: tools for microRNA genomics

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Mammalian microRNAs: experimental evaluation of novel and previously annotated genes

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

miRBase: annotating high confidence microRNAs using deep sequencing data

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

The expansion of the metazoan microRNA repertoire

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Evolution of microRNA diversity and regulation in animals

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

The deep evolution of metazoan microRNAs

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

TALEN-based knockout library for human microRNAs

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

MicroRNA maturation: stepwise processing and subcellular localization

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

The let-7 family of microRNAs

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Chromatin structure analyses identify miRNA promoters

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Structure and activity of putative intronic miRNA promoters

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

MicroRNA genes are transcribed by RNA polymerase II

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Identification of microRNAs of the herpesvirus family

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicer-dependent small RNAs

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

The nuclear RNase III Drosha initiates microRNA processing

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Processing of primary microRNAs by the Microprocessor complex

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

The Microprocessor complex mediates the genesis of microRNAs

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

The Drosha-DGCR8 complex in primary microRNA processing

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

The human DiGeorge syndrome critical region gene 8 and Its D. melanogaster homolog are required for miRNA biogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Canonical and alternate functions of the microRNA biogenesis machinery.

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Molecular cloning and expression analysis of a novel gene DGCR8 located in the DiGeorge syndrome chromosomal region

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Velo-cardio-facial syndrome: a review of 120 patients.

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

A novel type of RNase III family proteins in eukaryotes

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Mouse ribonuclease III. cDNA structure, expression analysis, and chromosomal location

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Human RNase III is a 160-kDa protein involved in preribosomal RNA processing

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Phosphorylation of the RNase III enzyme Drosha at Serine300 or Serine302 is required for its nuclear localization

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Crystallographic and modeling studies of RNase III suggest a mechanism for double-stranded RNA cleavage

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Single processing center models for human Dicer and bacterial RNase III

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Nucleolar localization of DGCR8 and identification of eleven DGCR8-associated proteins

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Characterization of DGCR8/Pasha, the essential cofactor for Drosha in primary miRNA processing

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Crystal structure of human DGCR8 core

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Heme is involved in microRNA processing

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

DGCR8 recognizes primary transcripts of microRNAs through highly cooperative binding and formation of higher-order structures

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Ferric, not ferrous, heme activates RNA-binding protein DGCR8 for primary microRNA processing.

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Processing of microRNA primary transcripts requires heme in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Beyond secondary structure: primary-sequence determinants license pri-miRNA hairpins for processing.

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Lower and upper stem-single-stranded RNA junctions together determine the Drosha cleavage site

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Hippo signaling regulates microprocessor and links cell-density-dependent miRNA biogenesis to cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Processing of intronic microRNAs

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Primary microRNA transcripts are processed co-transcriptionally.

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Primary microRNA transcript retention at sites of transcription leads to enhanced microRNA production

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Posttranscriptional crossregulation between Drosha and DGCR8.

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

'See-saw' expression of microRNA-198 and FSTL1 from a single transcript in wound healing.

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Drosha regulates neurogenesis by controlling neurogenin 2 expression independent of microRNAs

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Genome-wide identification of targets of the drosha-pasha/DGCR8 complex

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Phosphorylation of DGCR8 increases its intracellular stability and induces a progrowth miRNA profile

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Glycogen Synthase Kinase 3 Beta (GSK3β) Phosphorylates the RNAase III Enzyme Drosha at S300 and S302

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Histone deacetylase 1 enhances microRNA processing via deacetylation of DGCR8

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Acetylation of drosha on the N-terminus inhibits its degradation by ubiquitination.

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

MeCP2 suppresses nuclear microRNA processing and dendritic growth by regulating the DGCR8/Drosha complex

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

SMAD proteins control DROSHA-mediated microRNA maturation

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Modulation of microRNA processing by p53

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

TDP-43 regulates the microprocessor complex activity during in vitro neuronal differentiation

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

TDP-43 promotes microRNA biogenesis as a component of the Drosha and Dicer complexes

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

The multifunctional RNA-binding protein hnRNP A1 is required for processing of miR-18a

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Posttranscriptional regulation of miRNAs harboring conserved terminal loops.

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Nuclear export of microRNA precursors

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

A high-resolution structure of the pre-microRNA nuclear export machinery

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Exportin-5 mediates nuclear export of minihelix-containing RNAs

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Structural requirements for pre-microRNA binding and nuclear export by Exportin 5.

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Global microRNA elevation by inducible Exportin 5 regulates cell cycle entry.

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

DNA-damage-induced nuclear export of precursor microRNAs is regulated by the ATM-AKT pathway

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

A genetic defect in exportin-5 traps precursor microRNAs in the nucleus of cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Mammalian 5'-capped microRNA precursors that generate a single microRNA.

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Role for a bidentate ribonuclease in the initiation step of RNA interference

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Genetic and functional diversification of small RNA pathways in plants

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Dicer is essential for mouse development

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Characterization of Dicer-deficient murine embryonic stem cells.

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Alternative miRNA biogenesis pathways and the interpretation of core miRNA pathway mutants

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Dicer1 functions as a haploinsufficient tumor suppressor

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Recognition of the pre-miRNA structure by Drosophila Dicer-1.

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

The loop position of shRNAs and pre-miRNAs is critical for the accuracy of dicer processing in vivo

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Structural basis for double-stranded RNA processing by Dicer

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Dicer recognizes the 5' end of RNA for efficient and accurate processing

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Structure of the human Dicer-TRBP complex by electron microscopy

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Substrate-specific structural rearrangements of human Dicer

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Structural insights into RNA processing by the human RISC-loading complex

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Structural determinants of RNA recognition and cleavage by Dicer

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

The contributions of dsRNA structure to Dicer specificity and efficiency

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Dicer-1 and R3D1-L catalyze microRNA maturation in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Processing of pre-microRNAs by the Dicer-1-Loquacious complex in Drosophila cells

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Dicer partner proteins tune the length of mature miRNAs in flies and mammals

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Dicer-1, but not Loquacious, is critical for assembly of miRNA-induced silencing complexes

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

The miRNA pathway intrinsically controls self-renewal of Drosophila germline stem cells

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

The role of PACT in the RNA silencing pathway

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Differential roles of human Dicer-binding proteins TRBP and PACT in small RNA processing

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Substrate-specific kinetics of Dicer-catalyzed RNA processing

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

TRBP alters human precursor microRNA processing in vitro

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

The dsRNA protein kinase PKR: virus and cell control

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Phosphorylation of the human microRNA-generating complex mediates MAPK/Erk signaling

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

RETRACTED: A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

let-7 regulates Dicer expression and constitutes a negative feedback loop

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

A search for conserved sequences in coding regions reveals that the let-7 microRNA targets Dicer within its coding sequence

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Argonaute2, a link between genetic and biochemical analyses of RNAi

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

The rde-1 gene, RNA interference, and transposon silencing in C. elegans

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

The Structure of Human Argonaute-2 in Complex with miR-20a

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Structure of yeast Argonaute with guide RNA

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

The Crystal Structure of Human Argonaute2

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Crystal structure of Argonaute and its implications for RISC slicer activity

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Structural insights into mRNA recognition from a PIWI domain-siRNA guide complex

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Structure of the guide-strand-containing argonaute silencing complex

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Structural basis for 5'-nucleotide base-specific recognition of guide RNA by human AGO2

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Argonaute2 is the catalytic engine of mammalian RNAi

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

A dicer-independent miRNA biogenesis pathway that requires Ago catalysis

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Essential and overlapping functions for mammalian Argonautes in microRNA silencing

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

AGO4 regulates entry into meiosis and influences silencing of sex chromosomes in the male mouse germline

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Drosophila microRNAs are sorted into functionally distinct argonaute complexes after production by dicer-1.

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Sorting of Drosophila small silencing RNAs

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Hierarchical rules for Argonaute loading in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Sorting of Drosophila small silencing RNAs partitions microRNA* strands into the RNA interference pathway

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Structural determinants of miRNAs for RISC loading and slicer-independent unwinding

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Distinct mechanisms for microRNA strand selection by Drosophila Argonautes

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Two molecular features contribute to the Argonaute specificity for the microRNA and RNAi pathways in C. elegans

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Structural features of small RNA precursors determine Argonaute loading in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Characterization of endogenous human Argonautes and their miRNA partners in RNA silencing.

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

microRNAs associated with the different human Argonaute proteins

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

ATP-dependent human RISC assembly pathways

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

C3PO, an endoribonuclease that promotes RNAi by facilitating RISC activation

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

A Dicer-2-dependent 80s complex cleaves targeted mRNAs during RNAi in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

RISC assembly defects in the Drosophila RNAi mutant armitage.

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Human RISC couples microRNA biogenesis and posttranscriptional gene silencing

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

In vitro reconstitution of the human RISC-loading complex

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

A human, ATP-independent, RISC assembly machine fueled by pre-miRNA

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Slicer function of Drosophila Argonautes and its involvement in RISC formation

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Recognition of siRNA asymmetry by TAR RNA binding protein.

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

siRNA Repositioning for Guide Strand Selection by Human Dicer Complexes

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Precursor microRNA-programmed silencing complex assembly pathways in mammals

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Dicer is dispensable for asymmetric RISC loading in mammals

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Structure of C3PO and mechanism of human RISC activation

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Dual role for argonautes in microRNA processing and posttranscriptional regulation of microRNA expression.

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Cleavage of the siRNA passenger strand during RISC assembly in human cells

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

ATP requirements and small interfering RNA structure in the RNA interference pathway

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Hsc70/Hsp90 chaperone machinery mediates ATP-dependent RISC loading of small RNA duplexes

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Molecular mechanisms that funnel RNA precursors into endogenous small-interfering RNA and microRNA biogenesis pathways in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

The 3'-to-5' exoribonuclease Nibbler shapes the 3' ends of microRNAs bound to Drosophila Argonaute1.

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

The exoribonuclease Nibbler controls 3' end processing of microRNAs in Drosophila.

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Functional siRNAs and miRNAs Exhibit Strand Bias

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Asymmetry in the assembly of the RNAi enzyme complex

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Sequence features associated with microRNA strand selection in humans and flies

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Alternative processing of primary microRNA transcripts by Drosha generates 5' end variation of mature microRNA.

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Prolyl 4-hydroxylation regulates Argonaute 2 stability

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Hypoxia potentiates microRNA-mediated gene silencing through posttranslational modification of Argonaute2.

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Phosphorylation of Argonaute 2 at serine-387 facilitates its localization to processing bodies

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Akt-mediated phosphorylation of argonaute 2 downregulates cleavage and upregulates translational repression of MicroRNA targets

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2.

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Phosphorylation of human Argonaute proteins affects small RNA binding.

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

A transient reversal of miRNA-mediated repression controls macrophage activation

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Poly(ADP-ribose) regulates stress responses and microRNA activity in the cytoplasm.

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Reciprocal inhibition between intracellular antiviral signaling and the RNAi machinery in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

The let-7 target gene mouse lin-41 is a stem cell specific E3 ubiquitin ligase for the miRNA pathway protein Ago2

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

HSP90 protein stabilizes unloaded argonaute complexes and microscopic P-bodies in human cells

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Homeostatic control of Argonaute stability by microRNA availability

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

T cell activation induces proteasomal degradation of Argonaute and rapid remodeling of the microRNA repertoire.

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

The mammalian TRIM-NHL protein TRIM71/LIN-41 is a repressor of mRNA function

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Trim71 cooperates with microRNAs to repress Cdkn1a expression and promote embryonic stem cell proliferation

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

The ubiquitin ligase mLin41 temporally promotes neural progenitor cell maintenance through FGF signaling

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Argonaute2 expression is post-transcriptionally coupled to microRNA abundance

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Genetic variation in microRNA networks: the implications for cancer research

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

A functional genetic variant in microRNA-196a2 is associated with increased susceptibility of lung cancer in Chinese

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Polymorphic mature microRNAs from passenger strand of pre-miR-146a contribute to thyroid cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Common SNP in pre-miR-146a decreases mature miR expression and predisposes to papillary thyroid carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Diversifying microRNA sequence and function

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Human embryonic stem cells express a unique set of microRNAs

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Extensive post-transcriptional regulation of microRNAs and its implications for cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Post-transcriptional regulation of the let-7 microRNA during neural cell specification

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Selective blockade of microRNA processing by Lin28

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Structural basis of pre-let-7 miRNA recognition by the zinc knuckles of pluripotency factor Lin28

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Molecular basis for interaction of let-7 microRNAs with Lin28

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Lin28 recruits the TUTase Zcchc11 to inhibit let-7 maturation in mouse embryonic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

A role for the Perlman syndrome exonuclease Dis3l2 in the Lin28-let-7 pathway

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Mammalian DIS3L2 exoribonuclease targets the uridylated precursors of let-7 miRNAs

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Mono-uridylation of pre-microRNA as a key step in the biogenesis of group II let-7 microRNAs

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Selective stabilization of mammalian microRNAs by 3' adenylation mediated by the cytoplasmic poly(A) polymerase GLD-2.

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Degradation of host microRNAs by poxvirus poly(A) polymerase reveals terminal RNA methylation as a protective antiviral mechanism

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Modulation of microRNA processing and expression through RNA editing by ADAR deaminases

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

RNA editing of the microRNA-151 precursor blocks cleavage by the Dicer-TRBP complex

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Human RNA methyltransferase BCDIN3D regulates microRNA processing

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

MicroRNA turnover: when, how, and why.

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

MCPIP1 ribonuclease antagonizes dicer and terminates microRNA biogenesis through precursor microRNA degradation

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2.

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Degradation of microRNAs by a family of exoribonucleases in Arabidopsis

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Target-mediated protection of endogenous microRNAs in C. elegans

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Active turnover modulates mature microRNA activity in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Characterizing light-regulated retinal microRNAs reveals rapid turnover as a common property of neuronal microRNAs

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Human polynucleotide phosphorylase selectively and preferentially degrades microRNA-221 in human melanoma cells

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Eri1 regulates microRNA homeostasis and mouse lymphocyte development and antiviral function

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Murine cytomegalovirus encodes a miR-27 inhibitor disguised as a target

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Target RNA-directed trimming and tailing of small silencing RNAs

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Kinetic analysis reveals the fate of a microRNA following target regulation in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Long-term, efficient inhibition of microRNA function in mice using rAAV vectors

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Down-regulation of a host microRNA by a Herpesvirus saimiri noncoding RNA

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Selective degradation of host MicroRNAs by an intergenic HCMV noncoding RNA accelerates virus production

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Versatile microRNA biogenesis in animals and their viruses

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Mammalian mirtron genes

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Intronic microRNA precursors that bypass Drosha processing

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

MicroRNA biogenesis via splicing and exosome-mediated trimming in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

A human snoRNA with microRNA-like functions

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

A primate herpesvirus uses the integrator complex to generate viral microRNAs

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

A mammalian herpesvirus uses noncanonical expression and processing mechanisms to generate viral MicroRNAs

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

A novel miRNA processing pathway independent of Dicer requires Argonaute2 catalytic activity

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Conserved vertebrate mir-451 provides a platform for Dicer-independent, Ago2-mediated microRNA biogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Poly(A)-specific ribonuclease mediates 3'-end trimming of Argonaute2-cleaved precursor microRNAs

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Genomic analysis suggests that mRNA destabilization by the microprocessor is specialized for the auto-regulation of Dgcr8

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Post-transcriptional control of DGCR8 expression by the Microprocessor

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Diverse endonucleolytic cleavage sites in the mammalian transcriptome depend upon microRNAs, Drosha, and additional nucleases

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Expanding the role of Drosha to the regulation of viral gene expression

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

The Microprocessor controls the activity of mammalian retrotransposons

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

DGCR8 HITS-CLIP reveals novel functions for the Microprocessor

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Drosha-independent DGCR8/Pasha pathway regulates neuronal morphogenesis.

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

DICER- and AGO3-dependent generation of retinoic acid-induced DR2 Alu RNAs regulates human stem cell proliferation

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Argonaute proteins: functional insights and emerging roles

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Inefficient SRP interaction with a nascent chain triggers a mRNA quality control pathway

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Structure and function of Zucchini endoribonuclease in piRNA biogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

PIWI-interacting small RNAs: the vanguard of genome defence

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Functional association of the Microprocessor complex with the spliceosome

1 reference

https://api.crossref.org/works/10.1038%2FNRM3838

31 March 2020

Mechanisms of control of microRNA biogenesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25027649

12 December 2020

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