(Q34796058)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

title

DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

0 references

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Katalin Karikó

1 reference

21 January 2020

Dan R Littman

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Hiroki Kaneko

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Sami Dridi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Bradley D Gelfand

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Benjamin J Fowler

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Won Gil Cho

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Mark E Kleinman

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Steven L Ponicsan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Vince A Chiodo

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Jae Wook Yoo

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Dong-ki Lee

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Majda Hadziahmetovic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Ying Song

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Smita Misra

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Gautam Chaudhuri

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Frank W Buaas

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Robert E Braun

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

David R Hinton

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Qing Zhang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Hans E Grossniklaus

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Michele C Madigan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Ann H Milam

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Nikki L Justice

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Romulo J C Albuquerque

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Alexander D Blandford

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Sasha Bogdanovich

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Yoshio Hirano

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Jassir Witta

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Balamurali K Ambati

1 reference

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21 January 2020

Jennifer F Kugel

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

James A Goodrich

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Joshua L Dunaief

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Judit Z Baffi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Jayakrishna Ambati

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Elaine Fuchs

1 reference

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21 January 2020

language of work or name

English

0 references

publication date

6 February 2011

1 reference

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21 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

volume

471

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

issue

7338

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

page(s)

325-330

1 reference

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describes a project that uses

21 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3077055/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Generation of Cre transgenic mice with postnatal RPE-specific ocular expression

1 reference

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Canonical and alternate functions of the microRNA biogenesis machinery.

8 July 2018

1 reference

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Argonaute 2 in dopamine 2 receptor-expressing neurons regulates cocaine addiction

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

Caspase-dependent conversion of Dicer ribonuclease into a death-promoting deoxyribonuclease.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

Dicer1 functions as a haploinsufficient tumor suppressor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

Essential role for Argonaute2 protein in mouse oogenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

DICER1 mutations in familial pleuropulmonary blastoma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

CCR3 is a target for age-related macular degeneration diagnosis and therapy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

Chromatin remodeling at Alu repeats by epigenetic treatment activates silenced microRNA-512-5p with downregulation of Mcl-1 in human gastric cancer cells.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

Essential and overlapping functions for mammalian Argonautes in microRNA silencing

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

DGCR8-dependent microRNA biogenesis is essential for skin development

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

Dicer, Drosha, and outcomes in patients with ovarian cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicer-dependent small RNAs

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

Toll-like receptor 3 and geographic atrophy in age-related macular degeneration

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

Dicer inactivation leads to progressive functional and structural degeneration of the mouse retina

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

Conditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

Sequence- and target-independent angiogenesis suppression by siRNA via TLR3

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

Adeno-associated viral vectors and the retina

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

A Slicer-independent role for Argonaute 2 in hematopoiesis and the microRNA pathway

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

Annotation, submission and screening of repetitive elements in Repbase: RepbaseSubmitter and Censor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

The endocytic pathway mediates cell entry of dsRNA to induce RNAi silencing

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

The colorectal microRNAome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

Characterization of Dicer-deficient murine embryonic stem cells.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

The Microprocessor complex mediates the genesis of microRNAs

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

Argonaute2 is the catalytic engine of mammalian RNAi

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

Alu repeats and human genomic diversity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

Role for a bidentate ribonuclease in the initiation step of RNA interference

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

SINE and LINE within human centromeres.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

Founding mutations and Alu-mediated recombination in hereditary colon cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

Duplication of seven exons in LDL receptor gene caused by Alu-Alu recombination in a subject with familial hypercholesterolemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

Mutation in LDL receptor: Alu-Alu recombination deletes exons encoding transmembrane and cytoplasmic domains

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

Recombination at the human alpha-globin gene cluster: sequence features and topological constraints

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

Monoclonal antibodies to double-stranded RNA as probes of RNA structure in crude nucleic acid extracts

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

A de novo Alu insertion results in neurofibromatosis type 1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

Vascular endothelial growth factor and age-related macular degeneration: from basic science to therapy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

Expression and modulation of RPE cell membrane complement regulatory proteins.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

Dual role for argonautes in microRNA processing and posttranscriptional regulation of microRNA expression.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

The SINE-encoded mouse B2 RNA represses mRNA transcription in response to heat shock

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

The role of apoptosis in age-related macular degeneration

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

Establishment and maintenance of a heterochromatin domain

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

cDNAs derived from primary and small cytoplasmic Alu (scAlu) transcripts

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077055

26 October 2018

Identifiers

DOI

10.1038/NATURE09830

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

PubMed publication ID

21297615

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21297615%20AND%20SRC:MED&resulttype=core&format=json