(Q83940718)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16758333%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

title

Population-based analysis of methadone distribution and metabolism using an age-dependent physiologically based pharmacokinetic model (English)

1 reference

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29 January 2020

1 reference

1 reference

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29 January 2020

Feng Yang

1 reference

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29 January 2020

Xianping Tong

series ordinal

1 reference

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29 January 2020

D Gail McCarver

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16758333%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Daniel A Beard

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16758333%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

publication date

7 June 2006

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16758333%20AND%20SRC:MED&resulttype=core&format=json

Journal of Pharmacokinetics and Pharmacodynamics

29 January 2020

published in

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29 January 2020

volume

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29 January 2020

issue

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29 January 2020

page(s)

485-518

1 reference

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Disposition of methadone in methadone maintenance

29 January 2020

cites work

1 reference

12 December 2020

Interaction of methadone with substrates of human hepatic cytochrome P450 3A4.

1 reference

12 December 2020

Prediction of pharmacokinetic alterations caused by drug-drug interactions: metabolic interaction in the liver

1 reference

12 December 2020

A statistical analysis of the internal organ weights of normal Japanese people

1 reference

12 December 2020

Methadone--metabolism, pharmacokinetics and interactions

1 reference

12 December 2020

The use of plasma levels to optimize methadone maintenance treatment

1 reference

12 December 2020

Drug interactions with patient-controlled analgesia

1 reference

12 December 2020

The metabolic fate of the optical isomers of methadone

1 reference

12 December 2020

Steady-state pharmacokinetics of methadone in opioid addicts

1 reference

12 December 2020

Maturation and growth of renal function: dosing renally cleared drugs in children

1 reference

12 December 2020

Liver volume in children measured by computed tomography

1 reference

12 December 2020

Nomograms for the prediction of patient's plasma volume in plasma exchange therapy from height, weight, and hematocrit

1 reference

12 December 2020

Pharmacokinetics of methadone and its primary metabolite in 20 opiate addicts

1 reference

12 December 2020

Gross tissue weights in the human body by cadaver dissection

1 reference

12 December 2020

Enteral methadone to expedite fentanyl discontinuation and prevent opioid abstinence syndrome in the PICU.

1 reference

12 December 2020

Influence of plasma-protein binding on analgesic effect of methadone in rats with spontaneous withdrawal

1 reference

12 December 2020

Alpha 1-acid glycoprotein levels in human immunodeficiency virus-infected subjects on antiretroviral regimens

1 reference

12 December 2020

Characterization of age-related changes in body weight and organ weights from birth to adolescence in humans.

1 reference

12 December 2020

Methadone use in cancer patients with pain: a review

1 reference

12 December 2020

Estimation and prediction of blood volume in infants and children

1 reference

12 December 2020

Modeling interindividual variation in physiological factors used in PBPK models of humans

1 reference

12 December 2020

Methadone: a review of its pharmacokinetic/pharmacodynamic properties.

1 reference

12 December 2020

The gastrointestinal absorption of methadone in the rat

1 reference

12 December 2020

Protein binding predictions in infants

1 reference

12 December 2020

Perspectives in pharmacokinetics. Physiologically based pharmacokinetic modeling as a tool for drug development

1 reference

12 December 2020

The distribution of methadone in man.

1 reference

12 December 2020

Clinical pharmacokinetics of methadone

1 reference

12 December 2020

Standard splenic volume in children and young adults measured from CT images

1 reference

12 December 2020

Tolerance, withdrawal, and physical dependency after long-term sedation and analgesia of children in the pediatric intensive care unit

1 reference

12 December 2020

Prediction of drug disposition in infants and children by means of physiologically based pharmacokinetic (PBPK) modelling: theophylline and midazolam as model drugs

1 reference

12 December 2020

Disposition of methadone in man after a single oral dose

1 reference

12 December 2020

Evaluation of uncertainty in input parameters to pharmacokinetic models and the resulting uncertainty in output

1 reference

12 December 2020

The ontogeny of human drug-metabolizing enzymes: phase II conjugation enzymes and regulatory mechanisms

1 reference

12 December 2020

Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

1 reference

12 December 2020

Stereoselective pharmacokinetics of methadone in chronic pain patients

1 reference

12 December 2020

Involvement of CYP3A4, CYP2C8, and CYP2D6 in the metabolism of (R)- and (S)-methadone in vitro

1 reference

12 December 2020

The ontogeny of human drug-metabolizing enzymes: phase I oxidative enzymes

1 reference

12 December 2020

Methadone maintenance: a review and critique

1 reference

12 December 2020

Developmental expression of the major human hepatic CYP3A enzymes

1 reference

12 December 2020

Physiologically based pharmacokinetics in drug development and regulatory science: a workshop report (Georgetown University, Washington, DC, May 29-30, 2002).

1 reference

12 December 2020

A review of patients on methadone maintenance.

1 reference

12 December 2020

Use of relative weight and Body Mass Index for the determination of adiposity

1 reference

12 December 2020

Physiologically based pharmacokinetic (PBPK) modeling of caffeine and theophylline in neonates and adults: implications for assessing children's risks from environmental agents

1 reference

12 December 2020

Changes in brain weights during the span of human life: relation of brain weights to body heights and body weights

1 reference

12 December 2020

Human physiologically based pharmacokinetic model for propofol

1 reference

12 December 2020

Analysis of methadone disposition in the pregnant rat by means of a physiological flow model

1 reference

12 December 2020

Studies on the expression and metabolic capabilities of human liver cytochrome P450IIIA5 (HLp3)

1 reference

12 December 2020

Interindividual variability of the clinical pharmacokinetics of methadone: implications for the treatment of opioid dependence

1 reference

12 December 2020

Pharmacogenomics as an aspect of molecular autopsy for forensic pathology/toxicology: does genotyping CYP 2D6 serve as an adjunct for certifying methadone toxicity?

1 reference

12 December 2020

Steady-state pharmacokinetics of (R)- and (S)-methadone in methadone maintenance patients.

1 reference

12 December 2020

Methadone N-demethylation in human liver microsomes: lack of stereoselectivity and involvement of CYP3A4

1 reference

12 December 2020

Role of hepatic and intestinal cytochrome P450 3A and 2B6 in the metabolism, disposition, and miotic effects of methadone

1 reference

12 December 2020

Basic anatomical and physiological data for use in radiological protection: reference values. A report of age- and gender-related differences in the anatomical and physiological characteristics of reference individuals. ICRP Publication 89

1 reference

12 December 2020

The influence of age, sex, race, and body habitus on kidney weight in humans

1 reference

12 December 2020

Estimating the surface area of the human body.

1 reference

12 December 2020

Methadone as treatment for iatrogenic narcotic dependency in pediatric intensive care unit patients

1 reference

12 December 2020

Methadone plasma protein binding: alterations in cancer and displacement from alpha 1-acid glycoprotein

1 reference

12 December 2020

Pharmacokinetics and pharmacodynamics of methadone enantiomers after a single oral dose of racemate

1 reference

12 December 2020