(Q77653264)

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Normoxic induction of the hypoxia-inducible factor 1alpha by insulin and interleukin-1beta involves the phosphatidylinositol 3-kinase pathway

scientific article published on 01 February 2002

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7 December 2019

Normoxic induction of the hypoxia-inducible factor 1alpha by insulin and interleukin-1beta involves the phosphatidylinositol 3-kinase pathway (English)

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7 December 2019

Daniel P Stiehl

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7 December 2019

Thomas Hellwig-Bürgel

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Thomas Hellwig-Bürgel

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7 December 2019

Wolfgang Jelkmann

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Wolfgang Jelkmann

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7 December 2019

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Roland H Wenger

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7 December 2019

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1 February 2002

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7 December 2019

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7 December 2019

512

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7 December 2019

1-3

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7 December 2019

157-162

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7 December 2019

HIF-1, O(2), and the 3 PHDs: how animal cells signal hypoxia to the nucleus

1 reference

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7 January 2021

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

1 reference

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7 January 2021

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

1 reference

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7 January 2021

MAPK and Akt act cooperatively but independently on hypoxia inducible factor-1alpha in rasV12 upregulation of VEGF.

1 reference

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7 January 2021

p42/p44 MAP kinase module plays a key role in the transcriptional regulation of the vascular endothelial growth factor gene in fibroblasts

1 reference

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7 January 2021

p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1.

1 reference

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7 January 2021

Signaling angiogenesis via p42/p44 MAP kinase and hypoxia

1 reference

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7 January 2021

ERK activation upon hypoxia: involvement in HIF-1 activation

1 reference

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7 January 2021

Hypoxia induces the activation of the phosphatidylinositol 3-kinase/Akt cell survival pathway in PC12 cells: protective role in apoptosis

1 reference

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7 January 2021

Phosphatidylinositol 3-kinase signaling mediates angiogenesis and expression of vascular endothelial growth factor in endothelial cells

1 reference

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7 January 2021

Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1alpha/ARNT

1 reference

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7 January 2021

Hypoxia and interleukin-1beta stimulate vascular endothelial growth factor production in human proximal tubular cells

1 reference

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7 January 2021

Thrombin activates the hypoxia-inducible factor-1 signaling pathway in vascular smooth muscle cells: Role of the p22(phox)-containing NADPH oxidase

1 reference

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7 January 2021

The regulated expression of erythropoietin by two human hepatoma cell lines

1 reference

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7 January 2021

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

1 reference

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7 January 2021

Identification of a novel inhibitor of mitogen-activated protein kinase kinase

1 reference

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7 January 2021

Effects of chemotherapeutic and immunosuppressive drugs on the production of erythropoietin in human hepatoma cultures

1 reference

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7 January 2021

Oxygen-regulated transferrin expression is mediated by hypoxia-inducible factor-1.

1 reference

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7 January 2021

Hypoxia-induced VEGF enhances tumor survivability via suppression of serum deprivation-induced apoptosis

1 reference

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7 January 2021

Dephosphorylated hypoxia-inducible factor 1alpha as a mediator of p53-dependent apoptosis during hypoxia

1 reference

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7 January 2021

Insulin-like growth factors decrease oxygen-regulated erythropoietin production by human hepatoma cells (Hep G2)

1 reference

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7 January 2021

Insulin and insulin-like growth factor-I induce vascular endothelial growth factor mRNA expression via different signaling pathways.

1 reference

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7 January 2021

Distinct signaling pathways mediate phorbol-ester-induced and cytokine-induced inhibition of erythropoietin gene expression

1 reference

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7 January 2021

Transduction pathways involved in Hypoxia-Inducible Factor-1 phosphorylation and activation

1 reference

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7 January 2021

A non-hypoxic, ROS-sensitive pathway mediates TNF-alpha-dependent regulation of HIF-1alpha

1 reference

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7 January 2021

VEGF mRNA is reversibly stabilized by hypoxia and persistently stabilized in VEGF-overexpressing human tumor cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902247-0

7 January 2021

Mitogen-activated protein kinase kinase inhibitor PD98059 blocks the trans-activation but not the stabilization or DNA binding ability of hypoxia-inducible factor-1alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2902247-0

7 January 2021

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10.1016/S0014-5793(02)02247-0

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11852072%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11852072%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

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