(Q43761426)

26 November 2017

title

Dephosphorylated hypoxia-inducible factor 1alpha as a mediator of p53-dependent apoptosis during hypoxia (English)

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26 November 2017

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H Suzuki

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26 November 2017

A Tomida

series ordinal

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26 November 2017

T Tsuruo

series ordinal

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26 November 2017

language of work or name

English

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publication date

1 September 2001

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26 November 2017

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26 November 2017

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26 November 2017

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26 November 2017

page(s)

5779-5788

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Stabilization of wild-type p53 by hypoxia-inducible factor 1alpha

26 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204742

An intact HDM2 RING-finger domain is required for nuclear exclusion of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204742

Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204742

Mitochondrial reactive oxygen species trigger hypoxia-induced transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204742

p185erbB2 binds to GRP94 in vivo. Dissociation of the p185erbB2/GRP94 heterocomplex by benzoquinone ansamycins precedes depletion of p185erbB2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204742

Control of cell lineage-specific development and transcription by bHLH-PAS proteins

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204742

Peg3/Pw1 promotes p53-mediated apoptosis by inducing Bax translocation from cytosol to mitochondria

21 January 2018

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21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204742

Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204742

The MDM2 RING-finger domain is required to promote p53 nuclear export

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204742

The complexity of p53 modulation: emerging patterns from divergent signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204742

Functional interference between hypoxia and dioxin signal transduction pathways: competition for recruitment of the Arnt transcription factor

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204742

Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204742

Mitochondria and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204742

The Amino-terminal Domain of Heat Shock Protein 90 (hsp90) That Binds Geldanamycin Is an ATP/ADP Switch Domain That Regulates hsp90 Conformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204742

Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204742

Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204742

p53, the cellular gatekeeper for growth and division

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204742

Molecular chaperones: the busy life of Hsp90.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204742

Caspase structure, proteolytic substrates, and function during apoptotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204742

p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204742

Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204742

Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204742

The Hsp90 complex--a super-chaperone machine as a novel drug target

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204742

HIF-1: mediator of physiological and pathophysiological responses to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204742

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204742

Bcl-xL Regulates the Membrane Potential and Volume Homeostasis of Mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204742

The influence of tumor blood flow and microenvironmental factors on the efficacy of radiation, drugs and localized hyperthermia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204742

21 January 2018

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204742

p53 inhibits hypoxia-inducible factor-stimulated transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204742

7 January 2021

Hypoxia-inducible factor-1alpha mediates hypoxia-induced delayed neuronal death that involves p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204742

7 January 2021

Interstitial pH and pO2 gradients in solid tumors in vivo: high-resolution measurements reveal a lack of correlation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204742

7 January 2021

Regulation of the hypoxia-inducible transcription factor 1alpha by the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204742

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204742

1 reference

Dimensions Publication ID

26 November 2017

1031167781

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1 reference