(Q58320122)

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Rob Klompmaker

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Tea Vallenius

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Gert Rijksen

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René H. Medema

Journal of Biological Chemistry

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language of work or name

English

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publication date

25 July 2000

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published in

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volume

275

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issue

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page(s)

30638-30643

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cites work

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Principles of CDK regulation

21 January 2018

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A novel cyclin associates with MO15/CDK7 to form the CDK-activating kinase

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A cyclin associated with the CDK-activating kinase MO15

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MPF localization is controlled by nuclear export

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Control of cyclin B1 localization through regulated binding of the nuclear export factor CRM1

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Elimination of cdc2 phosphorylation sites in the cdc25 phosphatase blocks initiation of M-phase

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Fission yeast chk1 protein kinase links the rad checkpoint pathway to cdc2.

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rad-dependent response of the chk1-encoded protein kinase at the DNA damage checkpoint.

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Conservation of the Chk1 Checkpoint Pathway in Mammals: Linkage of DNA Damage to Cdk Regulation Through Cdc25

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Mitotic and G 2 Checkpoint Control: Regulation of 14-3-3 Protein Binding by Phosphorylation of Cdc25C on Serine-216

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Nuclear localization of Cdc25 is regulated by DNA damage and a 14-3-3 protein

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Nuclear localization of cyclin B1 controls mitotic entry after DNA damage

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Nuclear export of cyclin B1 and its possible role in the DNA damage-induced G2 checkpoint

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14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage

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14-3-3sigma is a p53-regulated inhibitor of G2/M progression

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WAF1, a potential mediator of p53 tumor suppression

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Requirement for p53 and p21 to sustain G2 arrest after DNA damage

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p21waf1 can block cells at two points in the cell cycle, but does not interfere with processive DNA-replication or stress-activated kinases

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Inhibition of cell proliferation by lithium is associated with interference in cdc2 activation

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Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function

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Alternative mechanisms of CAK assembly require an assembly factor or an activating kinase

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Inhibition of cyclin-dependent kinases by p21

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Nuclear Accumulation of p21Cip1 at the Onset of Mitosis: a Role at the G2/M-Phase Transition

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Both p16 and p21 families of cyclin-dependent kinase (CDK) inhibitors block the phosphorylation of cyclin-dependent kinases by the CDK-activating kinase

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p21Waf1 inhibits the activity of cyclin dependent kinase 2 by preventing its activating phosphorylation

21 January 2018

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Activation of human cyclin-dependent kinases in vitro

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Membrane localization of the kinase which phosphorylates p34cdc2 on threonine 14

21 January 2018

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Periodic changes in phosphorylation of the Xenopus cdc25 phosphatase regulate its activity

21 January 2018

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Regulation of the cdc25 protein during the cell cycle in Xenopus extracts

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Uncoupling of obesity from insulin resistance through a targeted mutation in aP2, the adipocyte fatty acid binding protein

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Activated polo-like kinase Plx1 is required at multiple points during mitosis in Xenopus laevis

21 January 2018

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