(Q46966682)

26 December 2017

title

Glyoxalase I is critical for human retinal capillary pericyte survival under hyperglycemic conditions (English)

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26 December 2017

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Antonia G Miller

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26 December 2017

Dawn G Smith

series ordinal

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26 December 2017

Manjunatha Bhat

series ordinal

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26 December 2017

Ram H Nagaraj

series ordinal

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26 December 2017

language of work or name

English

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publication date

27 February 2006

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26 December 2017

Journal of Biological Chemistry

published in

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26 December 2017

volume

281

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26 December 2017

issue

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26 December 2017

page(s)

11864-11871

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26 December 2017

The role of advanced glycation in the pathogenesis of diabetic retinopathy.

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Bax is increased in the retina of diabetic subjects and is associated with pericyte apoptosis in vivo and in vitro

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Activation of nuclear factor-kappaB induced by diabetes and high glucose regulates a proapoptotic program in retinal pericytes

21 January 2018

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Immunological evidence for methylglyoxal-derived modifications in vivo. Determination of antigenic epitopes

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Maillard reaction-mediated molecular damage to extracellular matrix and other tissue proteins in diabetes, aging, and uremia

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Advanced glycation end-products induce apoptosis of bovine retinal pericytes in culture: involvement of diacylglycerol/ceramide production and oxidative stress induction

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Methylglyoxal induces apoptosis mediated by reactive oxygen species in bovine retinal pericytes

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Effect of advanced glycation end products on accelerated apoptosis of retinal capillary cells under in vitro conditions

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Effect of dicarbonyl modification of fibronectin on retinal capillary pericytes

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Studies of rat and human retinas predict a role for the polyol pathway in human diabetic retinopathy

21 January 2018

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Overexpression of glyoxalase-I in bovine endothelial cells inhibits intracellular advanced glycation endproduct formation and prevents hyperglycemia-induced increases in macromolecular endocytosis

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A possible regulatory role of glyoxalase I in cell viability of human prostate cancer

21 January 2018

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Expression of glyoxalase I and II in normal and breast cancer tissues

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High concentrations of glucose induce synthesis of argpyrimidine in retinal endothelial cells

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The role of nitric oxide in the development of diabetic angiopathy

21 January 2018

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Diabetes-induced nitrative stress in the retina, and correction by aminoguanidine

21 January 2018

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Angiotensin II augments advanced glycation end product-induced pericyte apoptosis through RAGE overexpression

21 January 2018

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Evidence of high levels of methylglyoxal in cultured Chinese hamster ovary cells

21 January 2018

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Induction of apoptosis by glyoxal in human embryonic lung epithelial cell line L132.

21 January 2018

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Superoxide-mediated early oxidation and activation of ASK1 are important for initiating methylglyoxal-induced apoptosis process

21 January 2018

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21 January 2018

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Glyceraldehyde-3-phosphate dehydrogenase activity as an independent modifier of methylglyoxal levels in diabetes

21 January 2018

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Methylglyoxal enhances cisplatin-induced cytotoxicity by activating protein kinase Cdelta

21 January 2018

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21 January 2018

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Protecting the genome: defence against nucleotide glycation and emerging role of glyoxalase I overexpression in multidrug resistance in cancer chemotherapy

21 January 2018

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Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

21 January 2018

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Troglitazone reverses the inhibition of nitric oxide production by high glucose in cultured bovine retinal pericytes

21 January 2018

1 reference

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Nitric oxide inactivates glyoxalase I in cooperation with glutathione

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M513813200

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26 December 2017

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26 December 2017