(Q46673641)

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High-dose oral vitamin C partially replenishes vitamin C levels in patients with Type 2 diabetes and low vitamin C levels but does not improve endothelial dysfunction or insulin resistance

scientific article published on 26 August 2005

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Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16126809

High-dose oral vitamin C partially replenishes vitamin C levels in patients with Type 2 diabetes and low vitamin C levels but does not improve endothelial dysfunction or insulin resistance (English)

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16126809

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type 2 diabetes

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based on heuristic

inferred from title

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based on heuristic

inferred from title

insulin resistance

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based on heuristic

inferred from title

Michael J. Quon

10

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16126809

5

object named as

Julio A Panza

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16126809

Richard O. Cannon

6

object named as

Richard O Cannon

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16126809

author name string

Hui Chen

1

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Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16126809

Rajaram J Karne

2

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Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16126809

Gail Hall

3

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Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16126809

Umberto Campia

4

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Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16126809

Yaohui Wang

7

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Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16126809

Arie Katz

8

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Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16126809

Mark Levine

9

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Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16126809

publication date

26 August 2005

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Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16126809

American Journal of Physiology Heart and Circulatory Physiology

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Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16126809

290

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Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16126809

1

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Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16126809

H137-45

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16126809

Effect of supplementary antioxidant vitamin intake on carotid arterial wall intima-media thickness in a controlled clinical trial of cholesterol lowering.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Hemodynamic actions of insulin

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Insulin-mediated skeletal muscle vasodilation contributes to both insulin sensitivity and responsiveness in lean humans

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Role of oxidative stress in development of complications in diabetes

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Ascorbate restores endothelium-dependent vasodilation impaired by acute hyperglycemia in humans

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Oral antioxidant therapy improves endothelial function in Type 1 but not Type 2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

The effect of vitamin C supplementation on diabetic hyperlipidaemia: a double blind, crossover study

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Biochemistry and molecular cell biology of diabetic complications

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Endothelial dysfunction, inflammation, and insulin resistance: a focus on subjects at risk for type 2 diabetes

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

The glucose/insulin system and vitamin C: implications in insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Lack of effect of oral vitamin C on blood pressure, oxidative stress and endothelial function in Type II diabetes

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Lilly lecture 1987. The triumvirate: beta-cell, muscle, liver. A collusion responsible for NIDDM.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Increased response of renal perfusion to the antioxidant vitamin C in type 2 diabetes

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Antioxidant vitamins C and E improve endothelial function in children with hyperlipidemia: Endothelial Assessment of Risk from Lipids in Youth (EARLY) Trial

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

The metabolic syndrome and antioxidant concentrations: findings from the Third National Health and Nutrition Examination Survey

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Transport of vitamin C in animal and human cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Measuring reactive species and oxidative damage in vivo and in cell culture: how should you do it and what do the results mean?

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

MRC/BHF Heart Protection Study of antioxidant vitamin supplementation in 20,536 high-risk individuals: a randomised placebo-controlled trial

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Serial coronary angiographic evidence that antioxidant vitamin intake reduces progression of coronary artery atherosclerosis

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Quantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

The union of vascular and metabolic actions of insulin in sickness and in health.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Lack of long-term effect of vitamin C supplementation on blood pressure

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Beneficial effects of fenofibrate to improve endothelial dysfunction and raise adiponectin levels in patients with primary hypertriglyceridemia

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Vascular and metabolic effects of combined therapy with ramipril and simvastatin in patients with type 2 diabetes

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Additive beneficial effects of fenofibrate combined with atorvastatin in the treatment of combined hyperlipidemia

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Additive beneficial effects of losartan combined with simvastatin in the treatment of hypercholesterolemic, hypertensive patients

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Impaired insulin-mediated skeletal muscle blood flow in patients with NIDDM.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Ascorbic acid reverses endothelial vasomotor dysfunction in patients with coronary artery disease.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Vitamin C pharmacokinetics in healthy volunteers: evidence for a recommended dietary allowance

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

A new recommended dietary allowance of vitamin C for healthy young women

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Insulin action in vascular endothelium: potential mechanisms linking insulin resistance with hypertension

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Insulin-stimulated activation of eNOS is independent of Ca2+ but requires phosphorylation by Akt at Ser(1179).

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Insulin receptor substrate-1 and phosphoinositide-dependent kinase-1 are required for insulin-stimulated production of nitric oxide in endothelial cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Quantification of isoprostanes as indices of oxidant stress and the risk of atherosclerosis in humans

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Ascorbic acid reduces blood pressure and arterial stiffness in type 2 diabetes

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Endothelial function and oxidative stress

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Vitamin C as an antioxidant: evaluation of its role in disease prevention

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Cerivastatin improves insulin sensitivity and insulin secretion in early-state obese type 2 diabetes.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Role of endothelium-derived nitric oxide in the abnormal endothelium-dependent vascular relaxation of patients with essential hypertension.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Metabolic benefits deriving from chronic vitamin C supplementation in aged non-insulin dependent diabetics

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Obesity and body fat distribution induce endothelial dysfunction by oxidative stress: protective effect of vitamin C.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Oral L-arginine and vitamins E and C improve endothelial function in women with type 2 diabetes.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Glucose transporter isoforms GLUT1 and GLUT3 transport dehydroascorbic acid

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Nitric oxide release accounts for insulin's vascular effects in humans

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Clinical trials of antioxidants in atherosclerosis: are we doing the right thing?

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Insulin-mediated skeletal muscle vasodilation is nitric oxide dependent. A novel action of insulin to increase nitric oxide release

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Vitamin C improves endothelium-dependent vasodilation by restoring nitric oxide activity in essential hypertension.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Vitamin C Improves Endothelium-Dependent Vasodilation in Patients With Insulin-Dependent Diabetes Mellitus

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Vitamin C improves endothelium-dependent vasodilation in patients with non-insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Antioxidant vitamins C and E ameliorate hyperglycaemia-induced oxidative stress in coronary endothelial cells.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Molecular and physiologic actions of insulin related to production of nitric oxide in vascular endothelium

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Insulin-stimulated production of nitric oxide is inhibited by wortmannin. Direct measurement in vascular endothelial cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Oxidative stress and antioxidant defense in relation to the severity of diabetic polyneuropathy and cardiovascular autonomic neuropathy

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Effect of Vitamin C on Forearm Blood Flow and Glucose Metabolism in Essential Hypertension

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00768.2005

21 January 2018

Identifiers

10.1152/AJPHEART.00768.2005

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16126809

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16126809

ResearchGate publication ID

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