(Q45295140)

PubMed publication ID

15496672

11 December 2017

title

Biochemical, ultrastructural, and reversibility studies on huntingtin filaments isolated from mouse and human brain (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6730096&resulttype=core&format=json

12 May 2020

author

Fernando Moreno-Herrero

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6730096&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6730096&resulttype=core&format=json

12 May 2020

Miguel Diaz-Hernandez

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6730096&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6730096&resulttype=core&format=json

12 May 2020

Pilar Gómez-Ramos

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6730096&resulttype=core&format=json

12 May 2020

María A Morán

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6730096&resulttype=core&format=json

12 May 2020

Isidro Ferrer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6730096&resulttype=core&format=json

12 May 2020

Arturo M Baró

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6730096&resulttype=core&format=json

12 May 2020

Jesús Avila

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6730096&resulttype=core&format=json

12 May 2020

language of work or name

English

0 references

publication date

1 October 2004

1 reference

PubMed publication ID

15496672

11 December 2017

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6730096&resulttype=core&format=json

12 May 2020

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6730096&resulttype=core&format=json

12 May 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6730096&resulttype=core&format=json

12 May 2020

page(s)

9361-9371

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6730096&resulttype=core&format=json

Nuclear and neuropil aggregates in Huntington's disease: relationship to neuropathology.

12 May 2020

cites work

1 reference

12 December 2020

Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: implications for Huntington's disease pathology

1 reference

12 December 2020

Transgenic mice expressing a Huntington's disease mutation are resistant to quinolinic acid-induced striatal excitotoxicity

1 reference

12 December 2020

Assembly of A beta amyloid protofibrils: an in vitro model for a possible early event in Alzheimer's disease

1 reference

12 December 2020

Insoluble detergent-resistant aggregates form between pathological and nonpathological lengths of polyglutamine in mammalian cells

1 reference

12 December 2020

Inhibiting caspase cleavage of huntingtin reduces toxicity and aggregate formation in neuronal and nonneuronal cells

1 reference

12 December 2020

Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease

1 reference

12 December 2020

Glutamine repeats and neurodegeneration

1 reference

12 December 2020

Inhibition of fibrillization and accumulation of prefibrillar oligomers in mixtures of human and mouse alpha-synuclein

1 reference

12 December 2020

Aggresomes, inclusion bodies and protein aggregation

1 reference

12 December 2020

Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice

1 reference

12 December 2020

Targeting small Abeta oligomers: the solution to an Alzheimer's disease conundrum?

1 reference

12 December 2020

Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity

1 reference

12 December 2020

Identities of sequestered proteins in aggregates from cells with induced polyglutamine expression

1 reference

12 December 2020

Altered proteasomal function due to the expression of polyglutamine-expanded truncated N-terminal huntingtin induces apoptosis by caspase activation through mitochondrial cytochrome c release

1 reference

12 December 2020

Early degenerative changes in transgenic mice expressing mutant huntingtin involve dendritic abnormalities but no impairment of mitochondrial energy production

1 reference

12 December 2020

Accumulation of mutant huntingtin fragments in aggresome-like inclusion bodies as a result of insufficient protein degradation

1 reference

12 December 2020

Impairment of the ubiquitin-proteasome system by protein aggregation

1 reference

12 December 2020

Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease

1 reference

12 December 2020

SCA17, a novel autosomal dominant cerebellar ataxia caused by an expanded polyglutamine in TATA-binding protein

1 reference

12 December 2020

Proteasomal-dependent aggregate reversal and absence of cell death in a conditional mouse model of Huntington's disease.

1 reference

12 December 2020

Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct

1 reference

12 December 2020

Lessons from animal models of Huntington's disease

1 reference

12 December 2020

Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases

1 reference

12 December 2020

ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats

1 reference

12 December 2020

Ultrastructure of nuclear aggregates formed by expressing an expanded polyglutamine

1 reference

12 December 2020

Huntingtin spheroids and protofibrils as precursors in polyglutamine fibrilization

1 reference

12 December 2020

Proteases acting on mutant huntingtin generate cleaved products that differentially build up cytoplasmic and nuclear inclusions

1 reference

12 December 2020

Characterization by atomic force microscopy and cryoelectron microscopy of tau polymers assembled in Alzheimer's disease

1 reference

12 December 2020

Purification of polyglutamine aggregates and identification of elongation factor-1alpha and heat shock protein 84 as aggregate-interacting proteins.

1 reference

12 December 2020

Mutant huntingtin causes context-dependent neurodegeneration in mice with Huntington's disease.

1 reference

12 December 2020

Detergent-insoluble cortical Lewy body fibrils share epitopes with neurofilament and tau

1 reference

12 December 2020

Neuronal induction of the immunoproteasome in Huntington's disease.

1 reference

12 December 2020

Protein folding and misfolding

1 reference

12 December 2020

Characterization by atomic force microscopy of Alzheimer paired helical filaments under physiological conditions

1 reference

12 December 2020

Testing the ubiquitin-proteasome hypothesis of neurodegeneration in vivo.

1 reference

12 December 2020

The molecular pathology of Alzheimer's disease

1 reference

12 December 2020

A preparation of Alzheimer paired helical filaments that displays distinct tau proteins by polyacrylamide gel electrophoresis

1 reference

12 December 2020

Neuropathological classification of Huntington's disease

1 reference

12 December 2020

Alzheimer paired helical filaments: bulk isolation, solubility, and protein composition

1 reference

12 December 2020

Pathology and Biology of the Lewy Body

1 reference

12 December 2020

Twisted ribbon structure of paired helical filaments revealed by atomic force microscopy

1 reference

12 December 2020

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

1 reference

12 December 2020

Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract

1 reference

12 December 2020

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

1 reference

12 December 2020

Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo

1 reference

12 December 2020

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

1 reference

12 December 2020

Intranuclear Neuronal Inclusions: A Common Pathogenic Mechanism for Glutamine-Repeat Neurodegenerative Diseases?

1 reference

12 December 2020

1 reference

12 December 2020

Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

1 reference

12 December 2020

Mutant huntingtin expression in clonal striatal cells: dissociation of inclusion formation and neuronal survival by caspase inhibition.

1 reference

12 December 2020

10.1523/JNEUROSCI.2365-04.2004

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6730096&resulttype=core&format=json

release_dn4itmdegfhhdlc7d3l7mw7x5a

12 May 2020

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/dn4itmdegfhhdlc7d3l7mw7x5a

24 November 2022

mapped directly with Wikidata item

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6730096&resulttype=core&format=json

12 May 2020

PubMed publication ID

15496672

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6730096&resulttype=core&format=json