(Q45143151)

10 December 2017

title

An evolutionarily conserved target motif for immunoglobulin class-switch recombination (English)

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10 December 2017

Ali A Zarrin

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10 December 2017

Frederick W Alt

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10 December 2017

Jayanta Chaudhuri

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10 December 2017

Nicole Stokes

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10 December 2017

Dhruv Kaushal

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10 December 2017

Louis Du Pasquier

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10 December 2017

Ming Tian

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10 December 2017

language of work or name

English

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publication date

7 November 2004

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10 December 2017

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10 December 2017

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10 December 2017

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10 December 2017

page(s)

1275-1281

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Unraveling V(D)J recombination; insights into gene regulation

10 December 2017

cites work

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21 January 2018

Marginal-zone B cells

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What role for AID: mutator, or assembler of the immunoglobulin mutasome?

21 January 2018

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Mechanism and control of class-switch recombination

21 January 2018

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AID: how does it aid antibody diversity?

21 January 2018

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The mu switch region tandem repeats are important, but not required, for antibody class switch recombination

21 January 2018

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Immunoglobulin class-switch recombination in mice devoid of any S mu tandem repeat.

21 January 2018

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DNA sequences at immunoglobulin switch region recombination sites

21 January 2018

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Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

21 January 2018

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Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

21 January 2018

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De novo protein synthesis is required for the activation-induced cytidine deaminase function in class-switch recombination

21 January 2018

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De novo protein synthesis is required for activation-induced cytidine deaminase-dependent DNA cleavage in immunoglobulin class switch recombination

21 January 2018

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Uracil DNA glycosylase activity is dispensable for immunoglobulin class switch

21 January 2018

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Class-switch recombination: interplay of transcription, DNA deamination and DNA repair

21 January 2018

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AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

21 January 2018

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Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase

21 January 2018

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Human activation-induced cytidine deaminase causes transcription-dependent, strand-biased C to U deaminations

21 January 2018

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Transcription-targeted DNA deamination by the AID antibody diversification enzyme

21 January 2018

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AID mediates hypermutation by deaminating single stranded DNA.

21 January 2018

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Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand

21 January 2018

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DNA substrate length and surrounding sequence affect the activation-induced deaminase activity at cytidine

21 January 2018

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Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase.

21 January 2018

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Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice

21 January 2018

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Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination

21 January 2018

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Transcription-coupled events associating with immunoglobulin switch region chromatin

21 January 2018

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Replication protein A interacts with AID to promote deamination of somatic hypermutation targets

21 January 2018

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R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells

21 January 2018

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Cutting edge: DGYW/WRCH is a better predictor of mutability at G:C bases in Ig hypermutation than the widely accepted RGYW/WRCY motif and probably reflects a two-step activation-induced cytidine deaminase-triggered process

21 January 2018

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Discriminating intrinsic and antigen-selected mutational hotspots in immunoglobulin V genes

21 January 2018

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Replication protein A phosphorylation and the cellular response to DNA damage

21 January 2018

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AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching

21 January 2018

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Activation-induced deaminase (AID)-directed hypermutation in the immunoglobulin Smu region: implication of AID involvement in a common step of class switch recombination and somatic hypermutation

21 January 2018

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Absence of DNA polymerase eta reveals targeting of C mutations on the nontranscribed strand in immunoglobulin switch regions

21 January 2018

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The immune system of invertebrates and vertebrates

21 January 2018

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Microsites for immunoglobulin switch recombination breakpoints from Xenopus to mammals

21 January 2018

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An expressed neo(r) cassette provides required functions of the 1gamma2b exon for class switching.

21 January 2018

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The molecular genetics of bacteriophage P1

21 January 2018

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Palindromic but not G-rich sequences are targets of class switch recombination

21 January 2018

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Altered somatic hypermutation and reduced class-switch recombination in exonuclease 1-mutant mice

21 January 2018

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In Vitro Deamination of Cytosine to Uracil in Single-stranded DNA by Apolipoprotein B Editing Complex Catalytic Subunit 1 (APOBEC1)

21 January 2018

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Comparative analyses of immunoglobulin genes: surprises and portents

21 January 2018

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Mechanisms of chromosomal translocations in B cell lymphomas

21 January 2018

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AID is required for c-myc/IgH chromosome translocations in vivo

21 January 2018

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Growth retardation, early death, and DNA repair defects in mice deficient for the nucleotide excision repair enzyme XPF

21 January 2018

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Internal IgH class switch region deletions are position-independent and enhanced by AID expression

21 January 2018

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AID and mismatch repair in antibody diversification

21 January 2018

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7 January 2021

The influence of transcriptional orientation on endogenous switch region function

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7 January 2021

Transcription-induced cleavage of immunoglobulin switch regions by nucleotide excision repair nucleases in vitro

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7 January 2021

Chicken immunoglobulin mu-chain gene: germline organization and tandem repeats characteristic of class switch recombination

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7 January 2021

A class switch control region at the 3′ end of the immunoglobulin heavy chain locus

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7 January 2021

Identifiers

DOI

10.1038/NI1137

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10 December 2017

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