(Q45021537)

8 December 2017

title

AID is required for c-myc/IgH chromosome translocations in vivo (English)

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8 December 2017

Tasuku Honjo

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8 December 2017

Masamichi Muramatsu

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8 December 2017

Michel C. Nussenzweig

object named as

Michel C Nussenzweig

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8 December 2017

Almudena R Ramiro

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8 December 2017

Mila Jankovic

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8 December 2017

Thomas Eisenreich

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8 December 2017

Simone Difilippantonio

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8 December 2017

Selina Chen-Kiang

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8 December 2017

André Nussenzweig

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8 December 2017

language of work or name

English

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publication date

1 August 2004

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8 December 2017

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8 December 2017

volume

118

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8 December 2017

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8 December 2017

page(s)

431-438

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The SCID but not the RAG-2 gene product is required for S mu-S epsilon heavy chain class switching.

8 December 2017

cites work

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching

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12 October 2022

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Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase.

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Circular DNA is a product of the immunoglobulin class switch rearrangement

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Transcriptionally active c- myc oncogene is contained within NIARD, a DNA sequence associated with chromosome translocations in B-cell neoplasia

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Cellular myc oncogene is altered by chromosome translocation to an immunoglobulin locus in murine plasmacytomas and is rearranged similarly in human Burkitt lymphomas

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Deficiency in Msh2 affects the efficiency and local sequence specificity of immunoglobulin class-switch recombination: parallels with somatic hypermutation.

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12 October 2022

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Clonal diversification of primary BALB/c plasmacytomas harboring T(12;15) chromosomal translocations

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Ku70 is required for late B cell development and immunoglobulin heavy chain class switching

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Plasmacytomagenesis in mice: model of neoplastic development dependent upon chromosomal translocations

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https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Chromosomal translocations in human cancer.

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

V(D)J recombination in mouse thymocytes: Double-strand breaks near T cell receptor δ rearrangement signals

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis

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12 October 2022

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Constitutive expression of AID leads to tumorigenesis

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

The AID enzyme induces class switch recombination in fibroblasts

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Cancer-susceptibility genes. Gatekeepers and caretakers

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Lymph nodes and Peyer's patches of IL-6 transgenic BALB/c mice harbor T(12;15) translocated plasma cells that contain illegitimate exchanges between the immunoglobulin heavy-chain mu locus and c-myc

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Deletional remodeling of c-myc-deregulating chromosomal translocations

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Switch circular DNA formed in cytokine-treated mouse splenocytes: evidence for intramolecular DNA deletion in immunoglobulin class switching

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

IL-6 transgenic mouse model for extraosseous plasmacytoma

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Neoplastic development in plasma cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

AID enzyme-induced hypermutation in an actively transcribed gene in fibroblasts

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Translocations among antibody genes in human cancer

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Mechanisms of chromosomal translocations in B cell lymphomas

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Transcriptional activation of the translocated c-myc oncogene in burkitt lymphoma

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Transcriptionally active DNA region that rearranges frequently in murine lymphoid tumors.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Induction of cell cycle arrest and B cell terminal differentiation by CDK inhibitor p18(INK4c) and IL-6

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Generation of plasmacytomas with the chromosomal translocation t(12;15) in interleukin 6 transgenic mice.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Speed congenics: a classic technique in the fast lane (relatively speaking).

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Translocation, breakage and truncated transcripts of c-myc oncogene in murine plasmacytomas

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Mouse c-myc oncogene is located on chromosome 15 and translocated to chromosome 12 in plasmacytomas

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

V(D)J recombination: broken DNA molecules with covalently sealed (hairpin) coding ends in scid mouse thymocytes

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Somatic mutation of the CD95 gene in human B cells as a side-effect of the germinal center reaction

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Evidence for replicative repair of DNA double-strand breaks leading to oncogenic translocation and gene amplification

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Ku80 is required for immunoglobulin isotype switching

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Translocation joins c-myc and immunoglobulin gamma 1 genes in a Burkitt lymphoma revealing a third exon in the c-myc oncogene.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

RAG-1-deficient mice have no mature B and T lymphocytes

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Organization of immunoglobulin heavy chain genes and allelic deletion model

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Hepatitis C virus induces a mutator phenotype: enhanced mutations of immunoglobulin and protooncogenes

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Circular DNA is excised by immunoglobulin class switch recombination

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Translocation and rearrangements of the c-myc oncogene locus in human undifferentiated B-cell lymphomas

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2004.08.006

Identifiers

DOI

10.1016/J.CELL.2004.08.006

1 reference

8 December 2017

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