(Q44458788)

3 December 2017

title

Prediction of sensitivity to fluoropyrimidines by metabolic and target enzyme activities in gastric cancer (English)

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3 December 2017

Masanori Terashima

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3 December 2017

Hisataka Fujiwara

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3 December 2017

Akinori Takagane

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3 December 2017

Kaoru Abe

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3 December 2017

Takashi Irinoda

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3 December 2017

Tsutomu Nakaya

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3 December 2017

Hitoshi Yonezawa

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3 December 2017

Kenichi Oyama

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3 December 2017

Kazuyoshi Saito

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3 December 2017

Norio Kanzaki

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3 December 2017

Satoshi Ohtani

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3 December 2017

Tsuyoshi Nemoto

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3 December 2017

Yutaka Hoshino

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3 December 2017

Michihiko Kogure

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3 December 2017

Mitsukazu Gotoh

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3 December 2017

publication date

1 January 2003

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3 December 2017

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3 December 2017

volume

6 Suppl 1

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3 December 2017

page(s)

71-81

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Thymidine phosphorylase/platelet-derived endothelial cell growth factor expression associated with hepatic metastasis in gastric carcinoma

3 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS10120-003-0221-Z

Quantitative measurement of thymidylate synthase and dihydropyrimidine dehydrogenase mRNA level in gastric cancer by real-time RT-PCR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10120-003-0221-Z

Relationship between protein levels and gene expression of dihydropyrimidine dehydrogenase in human tumor cells during growth in culture and in nude mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10120-003-0221-Z

Thymidylate synthase gene polymorphism determines response and toxicity of 5-FU chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10120-003-0221-Z

Lack of correlation between thymidylate synthase levels in primary colorectal tumours and subsequent response to chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10120-003-0221-Z

Predictive value of thymidylate synthase and dihydropyrimidine dehydrogenase

21 January 2018

1 reference

12 December 2020

Phase II study of UFT plus leucovorin in colorectal cancer

1 reference

12 December 2020

Inhibitory effects of pyrimidine, barbituric acid and pyridine derivatives on 5-fluorouracil degradation in rat liver extracts

1 reference

12 December 2020

Heterogeneity and clinical role of thymidine phosphorylase activity in gastric cancer

1 reference

12 December 2020

A role for dihydropyrimidine dehydrogenase and thymidylate synthase in tumour sensitivity to fluorouracil

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12 December 2020

Metabolism and mechanism of action of 5-fluorouracil

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12 December 2020

Effect of uracil and its derivatives on antitumor activity of 5-fluorouracil and 1-(2-tetrahydrofuryl)-5-fluorouracil

1 reference

12 December 2020

A multifactorial approach including tumoural epidermal growth factor receptor, p53, thymidylate synthase and dihydropyrimidine dehydrogenase to predict treatment outcome in head and neck cancer patients receiving 5-fluorouracil

1 reference

12 December 2020

Discrepancies between the gene expression, protein expression, and enzymatic activity of thymidylate synthase and dihydropyrimidine dehydrogenase in human gastrointestinal cancers and adjacent normal mucosa.

1 reference

12 December 2020

Thymidylate synthase and drug resistance

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12 December 2020

Role of thymidine phosphorylase activity in the angiogenic effect of platelet derived endothelial cell growth factor/thymidine phosphorylase.

1 reference

12 December 2020

Thymidylate synthase mRNA level in adenocarcinoma of the stomach: a predictor for primary tumor response and overall survival

1 reference

12 December 2020

Dihydropyrimidine dehydrogenase activity and messenger RNA level may be related to the antitumor effect of 5-fluorouracil on human tumor xenografts in nude mice.

1 reference

12 December 2020

Roles of thymidylate synthase and dihydropyrimidine dehydrogenase in tumor progression and sensitivity to 5-fluorouracil in human gastric cancer

1 reference

12 December 2020

Dihydropyrimidine dehydrogenase, multidrug resistance-associated protein, and thymidylate synthase gene expression levels can predict 5-fluorouracil resistance in human gastrointestinal cancer cells.

1 reference

12 December 2020

Clinical application of biochemical modulation in cancer chemotherapy: biochemical modulation for 5-FU

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12 December 2020

Inhibition by oxonic acid of gastrointestinal toxicity of 5-fluorouracil without loss of its antitumor activity in rats

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12 December 2020

The usefulness of the ATP assay with serum-free culture for chemosensitivity testing of gastrointestinal cancer

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12 December 2020

Preclinical antitumor efficacy of S-1: a new oral formulation of 5-fluorouracil on human tumor xenografts

1 reference

12 December 2020

Development of a novel form of an oral 5-fluorouracil derivative (S-1) directed to the potentiation of the tumor selective cytotoxicity of 5-fluorouracil by two biochemical modulators

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12 December 2020

Positive correlation between the efficacy of capecitabine and doxifluridine and the ratio of thymidine phosphorylase to dihydropyrimidine dehydrogenase activities in tumors in human cancer xenografts

1 reference

12 December 2020

Antitumor activity of 1 M tegafur-0.4 M 5-chloro-2,4-dihydroxypyridine-1 M potassium oxonate (S-1) against human colon carcinoma orthotopically implanted into nude rats

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12 December 2020

The expression of thymidine phosphorylase/platelet-derived endothelial cell growth factor is correlated to angiogenesis in breast cancer

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12 December 2020

Thymidylate synthase (TS) and ribonucleotide reductase (RNR) may be involved in acquired resistance to 5-fluorouracil (5-FU) in human cancer xenografts in vivo

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12 December 2020

Clinical pharmacokinetics of 5-fluorouracil and its metabolites in plasma, urine, and bile

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12 December 2020

Severe neurotoxicity following 5-fluorouracil-based chemotherapy in a patient with dihydropyrimidine dehydrogenase deficiency

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12 December 2020

Japanese Classification of Gastric Carcinoma - 2nd English Edition -

1 reference

12 December 2020

Phase II study of S-1, a novel oral derivative of 5-fluorouracil, in advanced gastric cancer. For the S-1 Cooperative Gastric Cancer Study Group

1 reference

12 December 2020

Prediction of response to 5'-deoxy-5-fluorouridine (5'-DFUR) in patients with inoperable advanced gastric cancer by immunostaining of thymidine phosphorylase/platelet-derived endothelial cell growth factor

1 reference

12 December 2020

In vivo kinetics of thymidylate synthetase inhibition of 5-fluorouracil-sensitive and -resistant murine colon adenocarcinomas.

1 reference

12 December 2020

Late phase II study of novel oral fluoropyrimidine anticancer drug S-1 (1 M tegafur-0.4 M gimestat-1 M otastat potassium) in advanced gastric cancer patients

1 reference

12 December 2020

Phase II study of oral eniluracil, 5-fluorouracil, and leucovorin in patients with advanced colorectal carcinoma

1 reference

12 December 2020

Response to fluorouracil therapy in cancer patients: the role of tumoral dihydropyrimidine dehydrogenase activity

1 reference

12 December 2020

Relationship between dihydropyrimidine dehydrogenase activity and plasma 5-fluorouracil levels with evidence for circadian variation of enzyme activity and plasma drug levels in cancer patients receiving 5-fluorouracil by protracted continuous infus

1 reference

12 December 2020

Pharmacokinetic, oral bioavailability, and safety study of fluorouracil in patients treated with 776C85, an inactivator of dihydropyrimidine dehydrogenase

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12 December 2020

Effect of uracil on metabolism of 5-fluorouracil in vitro

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12 December 2020

Tumor angiogenesis and expression of thymidine phosphorylase/platelet derived endothelial cell growth factor in human gastric carcinoma

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12 December 2020

Uracil-ftorafur: an oral fluoropyrimidine active in colorectal cancer

1 reference

12 December 2020

Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors

1 reference

12 December 2020

Dihydropyrimidine dehydrogenase activity in hepatocellular carcinoma: implication in 5-fluorouracil-based chemotherapy

1 reference

12 December 2020

Fluorinated pyrimidines, a new class of tumour-inhibitory compounds

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12 December 2020

Preferential activation of capecitabine in tumor following oral administration to colorectal cancer patients

1 reference

12 December 2020

Pharmacokinetic study of S-1, a novel oral fluorouracil antitumor drug

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12 December 2020

Clinicopathological and prognostic significance of thymidine phosphorylase expression in gastric carcinoma

1 reference

12 December 2020

Clinicopathologic and prognostic significance of an angiogenic factor, thymidine phosphorylase, in human colorectal carcinoma

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12 December 2020

The role of thymidylate synthase expression in prognosis and outcome of adjuvant chemotherapy in patients with rectal cancer

1 reference

12 December 2020

Fluorinated pyrimidine nucleosides. 3. Synthesis and antitumor activity of a series of 5'-deoxy-5-fluoropyrimidine nucleosides

1 reference

12 December 2020

Prognostic value of tumoral thymidylate synthase and p53 in metastatic colorectal cancer patients receiving fluorouracil-based chemotherapy: phenotypic and genotypic analyses.

1 reference

12 December 2020

Role of thymidine phosphorylase and dihydropyrimidine dehydrogenase in tumour progression and sensitivity to doxifluridine in gastric cancer patients

1 reference

12 December 2020

10.1007/S10120-003-0221-Z

Identifiers

DOI

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3 December 2017

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