(Q44454872)

3 December 2017

title

Oxidative stress contributes to arsenic-induced telomere attrition, chromosome instability, and apoptosis (English)

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3 December 2017

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Maria A Blasco

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Lin Liu

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3 December 2017

James R Trimarchi

series ordinal

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3 December 2017

Paula Navarro

series ordinal

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3 December 2017

David L Keefe

series ordinal

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3 December 2017

language of work or name

English

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publication date

26 May 2003

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Journal of Biological Chemistry

3 December 2017

published in

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3 December 2017

volume

278

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3 December 2017

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3 December 2017

page(s)

31998-32004

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Arsenic disrupts cellular levels of p53 and mdm2: a potential mechanism of carcinogenesis

3 December 2017

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1 reference

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Active oxygen species are involved in the induction of micronuclei by arsenite in XRS-5 cells

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Mutagenicity of arsenic in mammalian cells: role of reactive oxygen species

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Involvement of reactive oxygen species and caspase 3 activation in arsenite-induced apoptosis

21 January 2018

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Induction of oxyradicals by arsenic: implication for mechanism of genotoxicity

21 January 2018

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Mitochondrial control of cell death

21 January 2018

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Telomere states and cell fates

21 January 2018

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p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis

21 January 2018

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Telomeres, telomerase, and cancer: life on the edge of genomic stability

21 January 2018

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Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Telomeres shorten during ageing of human fibroblasts

21 January 2018

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Telomeres in the mouse have large inter-chromosomal variations in the number of T2AG3 repeats

21 January 2018

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Mammalian Telomerase: Catalytic Subunit and Knockout Mice

21 January 2018

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Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

21 January 2018

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Essential role of mouse telomerase in highly proliferative organs

21 January 2018

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Disease states associated with telomerase deficiency appear earlier in mice with short telomeres

21 January 2018

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Telomere shortening in mTR-/- embryos is associated with failure to close the neural tube

21 January 2018

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An essential role for functional telomeres in mouse germ cells during fertilization and early development

21 January 2018

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Bax-induced cytochrome C release from mitochondria is independent of the permeability transition pore but highly dependent on Mg2+ ions

21 January 2018

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Restoration of telomerase activity rescues chromosomal instability and premature aging in Terc-/- mice with short telomeres.

21 January 2018

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Telomere shortening and apoptosis in telomerase-inhibited human tumor cells

21 January 2018

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Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death

21 January 2018

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Human telomerase activation requires two independent interactions between telomerase RNA and telomerase reverse transcriptase

21 January 2018

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Telomere shortening triggers a p53-dependent cell cycle arrest via accumulation of G-rich single stranded DNA fragments.

21 January 2018

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Creation of human tumour cells with defined genetic elements

21 January 2018

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Cell senescence and cancer

21 January 2018

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Balancing instability: dual roles for telomerase and telomere dysfunction in tumorigenesis

21 January 2018

1 reference

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N-acetyl-L-cysteine is a pluripotent protector against cell death and enhancer of trophic factor-mediated cell survival in vitro

21 January 2018

1 reference

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Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice

21 January 2018

1 reference

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The Shortest Telomere, Not Average Telomere Length, Is Critical for Cell Viability and Chromosome Stability

21 January 2018

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Carcinogenicity, teratogenicity and mutagenicity of arsenic.

21 January 2018

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Toxicity of sodium arsenite in mouse embryos in vitro and its influence on radiation risk

21 January 2018

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Comparative studies of chromosomal aberration induced by trivalent and pentavalent arsenic

21 January 2018

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Arsenite induces apoptosis via a direct effect on the mitochondrial permeability transition pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303553200

Mitochondrial dysfunction leads to telomere attrition and genomic instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303553200

Mild Hyperoxia Shortens Telomeres and Inhibits Proliferation of Fibroblasts: A Model for Senescence?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303553200

Cytochrome c release from mitochondria of early postimplantation murine embryos exposed to 4-hydroperoxycyclophosphamide, heat shock, and staurosporine

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M303553200

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3 December 2017

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