(Q44224221)

1 December 2017

title

Delta MEKK3:ER* activation induces a p38 alpha/beta 2-dependent cell cycle arrest at the G2 checkpoint (English)

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1 December 2017

Andrew P Garner

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1 December 2017

Claire R Weston

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1 December 2017

Daniel E Todd

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1 December 2017

Kathryn Balmanno

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1 December 2017

Simon J Cook

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1 December 2017

language of work or name

English

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publication date

1 November 2002

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1 December 2017

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1 December 2017

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1 December 2017

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1 December 2017

page(s)

8089-8104

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Regulation of cell cycle progression by Swe1p and Hog1p following hypertonic stress

1 December 2017

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7 January 2021

Sustained MAP kinase activation is required for the expression of cyclin D1, p21Cip1 and a subset of AP-1 proteins in CCL39 cells

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Cell cycle arrest and DNA endoreduplication following p21Waf1/Cip1 expression

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The role of inhibitory phosphorylation of CDC2 following DNA replication block and radiation-induced damage in human cells

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Human Myt1 Is a Cell Cycle-regulated Kinase That Inhibits Cdc2 but Not Cdk2 Activity

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7 January 2021

Radiation-induced cell cycle arrest compromised by p21 deficiency

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7 January 2021

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

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7 January 2021

Checkpoints controlling mitosis

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7 January 2021

Regulation of cell cycle re-entry by growth, survival and stress signalling pathways

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7 January 2021

SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1

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7 January 2021

Signal transduction by the JNK group of MAP kinases

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7 January 2021

Characterization of the mitogen-activated protein kinase kinase 4 (MKK4)/c-Jun NH2-terminal kinase 1 and MKK3/p38 pathways regulated by MEK kinases 2 and 3. MEK kinase 3 activates MKK3 but does not cause activation of p38 kinase in vivo

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7 January 2021

MEK kinase 3 directly activates MKK6 and MKK7, specific activators of the p38 and c-Jun NH2-terminal kinases

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7 January 2021

The Drosophila cell cycle gene fizzy is required for normal degradation of cyclins A and B during mitosis and has homology to the CDC20 gene of Saccharomyces cerevisiae

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7 January 2021

Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

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7 January 2021

Nuclear Accumulation of p21Cip1 at the Onset of Mitosis: a Role at the G2/M-Phase Transition

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7 January 2021

WAF1, a potential mediator of p53 tumor suppression

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7 January 2021

Cell cycle checkpoints: preventing an identity crisis

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7 January 2021

Cell cycle arrest and reversion of Ras-induced transformation by a conditionally activated form of mitogen-activated protein kinase kinase kinase 3.

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7 January 2021

Selective Activation of p38 Mitogen-activated Protein (MAP) Kinase Isoforms by the MAP Kinase Kinases MKK3 and MKK6

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7 January 2021

Identification of a novel inhibitor of mitogen-activated protein kinase kinase

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7 January 2021

The MO15 gene encodes the catalytic subunit of a protein kinase that activates cdc2 and other cyclin-dependent kinases (CDKs) through phosphorylation of Thr161 and its homologues

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7 January 2021

Human cyclin A is required for mitosis until mid prophase

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7 January 2021

Cyclin a is required for the onset of DNA replication in mammalian fibroblasts

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7 January 2021

Cyclin is degraded by the ubiquitin pathway

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7 January 2021

Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis

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7 January 2021

Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit.

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7 January 2021

Cdk2 kinase is required for entry into mitosis as a positive regulator of Cdc2-cyclin B kinase activity

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7 January 2021

A novel DNA damage checkpoint involving post-transcriptional regulation of cyclin A expression

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7 January 2021

Induction of metaphase arrest in cleaving Xenopus embryos by MAP kinase

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7 January 2021

Translocation of cyclin B1 to the nucleus at prophase requires a phosphorylation-dependent nuclear import signal

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7 January 2021

Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

Inhibition of cyclin-dependent kinases by p21

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

p53 regulates a G2 checkpoint through cyclin B1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

Role of inhibitory CDC2 phosphorylation in radiation-induced G2 arrest in human cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

c-Jun transactivates the promoter of the human p21(WAF1/Cip1) gene by acting as a superactivator of the ubiquitous transcription factor Sp1.

1 reference

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7 January 2021

How proteolysis drives the cell cycle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

Dual Mechanisms for the Inhibition of E2F Binding to RB by Cyclin-Dependent Kinase-Mediated RB Phosphorylation

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7 January 2021

Requirement for the MAP kinase kinase/MAP kinase cascade in Xenopus oocyte maturation.

1 reference

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7 January 2021

Regulation of APC activity by phosphorylation and regulatory factors

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7 January 2021

Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

Requirement for phosphorylation of cyclin B1 for Xenopus oocyte maturation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

Nuclear localization of Cdc25 is regulated by DNA damage and a 14-3-3 protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

Linkage of ATM to cell cycle regulation by the Chk2 protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

p21waf1 can block cells at two points in the cell cycle, but does not interfere with processive DNA-replication or stress-activated kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

Myt1: a membrane-associated inhibitory kinase that phosphorylates Cdc2 on both threonine-14 and tyrosine-15.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

p38 MAP kinases: beyond the stress response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

Human cyclin E, a nuclear protein essential for the G1-to-S phase transition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

The G(2) checkpoint is maintained by redundant pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

Identification of a 95-kDa WEE1-like tyrosine kinase in HeLa cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

UVB induced cell cycle checkpoints in an early stage human melanoma line, WM35.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

Isolation of a human cyclin cDNA: evidence for cyclin mRNA and protein regulation in the cell cycle and for interaction with p34cdc2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

1 reference

7 January 2021

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

Cyclin-dependent kinases are inactivated by a combination of p21 and Thr-14/Tyr-15 phosphorylation after UV-induced DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

Negative regulation of mitosis by wee1+, a gene encoding a protein kinase homolog

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

Chfr defines a mitotic stress checkpoint that delays entry into metaphase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

1 reference

7 January 2021

Inhibitors of mammalian G1 cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

ets-2 is a target for an akt (Protein kinase B)/jun N-terminal kinase signaling pathway in macrophages of motheaten-viable mutant mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

Role of phosphorylation in p34cdc2 activation: identification of an activating kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

Activation of the protein kinase p38 in the spindle assembly checkpoint and mitotic arrest.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

Regulation of Rb and E2F by signal transduction cascades: divergent effects of JNK1 and p38 kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

HuR regulates cyclin A and cyclin B1 mRNA stability during cell proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

Involvement of the MKK6-p38gamma cascade in gamma-radiation-induced cell cycle arrest

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

Role of p38 and JNK mitogen-activated protein kinases in the activation of ternary complex factors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

c-Jun regulates cell cycle progression and apoptosis by distinct mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

Raf-Induced Proliferation or Cell Cycle Arrest Is Determined by the Level of Raf Activity with Arrest Mediated by p21Cip1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

p21 is a universal inhibitor of cyclin kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

Maintenance of G2 arrest in the Xenopus oocyte: a role for 14-3-3-mediated inhibition of Cdc25 nuclear import

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

Mekk3 is essential for early embryonic cardiovascular development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206000

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1206000

1 reference

1 December 2017

1 reference