(Q43252074)

17 November 2017

title

Hypoxia stimulates lactate release and modulates monocarboxylate transporter (MCT1, MCT2, and MCT4) expression in human adipocytes (English)

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17 November 2017

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Fátima Pérez de Heredia

series ordinal

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17 November 2017

I Stuart Wood

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17 November 2017

Paul Trayhurn

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17 November 2017

publication date

30 October 2009

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17 November 2017

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17 November 2017

volume

459

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17 November 2017

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17 November 2017

page(s)

509-518

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Comparison of hypoxia transcriptome in vitro with in vivo gene expression in human bladder cancer

17 November 2017

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Changes in MCT 1, MCT 4, and LDH expression are tissue specific in rats after long-term hypobaric hypoxia

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Hypoxia decreases insulin signaling pathways in adipocytes

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Lactate boosts TLR4 signaling and NF-kappaB pathway-mediated gene transcription in macrophages via monocarboxylate transporters and MD-2 up-regulation

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Adipocytes as regulators of energy balance and glucose homeostasis

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Reduced adipose tissue oxygenation in human obesity: evidence for rarefaction, macrophage chemotaxis, and inflammation without an angiogenic response

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The SLC16 monocaboxylate transporter family

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12 December 2020

Dysregulation of the expression and secretion of inflammation-related adipokines by hypoxia in human adipocytes

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Hypoxia dysregulates the production of adiponectin and plasminogen activator inhibitor-1 independent of reactive oxygen species in adipocytes

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The SLC16 gene family?from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond

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Lactate induces insulin resistance in skeletal muscle by suppressing glycolysis and impairing insulin signaling

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Inflammation and metabolic disorders

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12 December 2020

The plasma membrane lactate transporter MCT4, but not MCT1, is up-regulated by hypoxia through a HIF-1alpha-dependent mechanism.

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12 December 2020

Insulin resistance in obesity is associated with elevated basal lactate levels and diminished lactate appearance following intravenous glucose and insulin

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12 December 2020

Hypoxia is a potential risk factor for chronic inflammation and adiponectin reduction in adipose tissue of ob/ob and dietary obese mice

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Lactate release from adipose tissue and skeletal muscle in vivo: defective insulin regulation in insulin-resistant obese women

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Gene expression profiling of the long-term adaptive response to hypoxia in the gills of adult zebrafish.

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Obesity in C57BL/6J mice is characterized by adipose tissue hypoxia and cytotoxic T-cell infiltration.

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A Novel Serum Protein Similar to C1q, Produced Exclusively in Adipocytes

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Increases in muscle MCT are associated with reductions in muscle lactate after a single exercise session in humans

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Lactate inhibits lipolysis in fat cells through activation of an orphan G-protein-coupled receptor, GPR81

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Lactate sensitive transcription factor network in L6 cells: activation of MCT1 and mitochondrial biogenesis.

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Lactate transport in rat adipocytes: identification of monocarboxylate transporter 1 (MCT1) and its modulation during streptozotocin-induced diabetes

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Expression of monocarboxylate transporter MCT1 in normal and neoplastic human CNS tissues

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12 December 2020

PCR arrays identify metallothionein-3 as a highly hypoxia-inducible gene in human adipocytes

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12 December 2020

10.1007/S00424-009-0750-3

Identifiers

DOI

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17 November 2017

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