(Q41903719)

English

Prodeath signaling of G protein-coupled receptor kinase 2 in cardiac myocytes after ischemic stress occurs via extracellular signal-regulated kinase-dependent heat shock protein 90-mediated mitochondrial targeting

scientific article published on 6 March 2013

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Prodeath signaling of G protein-coupled receptor kinase 2 in cardiac myocytes after ischemic stress occurs via extracellular signal-regulated kinase-dependent heat shock protein 90-mediated mitochondrial targeting (English)

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

G protein-coupled receptor

0 references

7

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author name string

Mai Chen

1

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Priscila Y Sato

2

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

J Kurt Chuprun

3

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Raymond J Peroutka

4

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Nicholas J Otis

5

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Jessica Ibetti

6

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Shi Pan

7

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Shey-Shing Sheu

8

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Erhe Gao

9

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Walter J Koch

10

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

publication date

6 March 2013

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Circulation Research

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

112

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

8

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

1121-1134

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Determining the absolute requirement of G protein-coupled receptor kinase 5 for pathological cardiac hypertrophy: short communication

1 reference

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5 June 2018

Mitochondrial localization unveils a novel role for GRK2 in organelle biogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3908784

5 June 2018

G protein-coupled receptor kinases in normal and failing myocardium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3908784

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A novel and efficient model of coronary artery ligation and myocardial infarction in the mouse

1 reference

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5 June 2018

Level of G protein–Coupled Receptor Kinase-2 Determines Myocardial Ischemia/Reperfusion Injury via Pro- and Anti-Apoptotic Mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3908784

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betaARKct: a therapeutic approach for improved adrenergic signaling and function in heart disease

1 reference

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5 June 2018

The complex G protein-coupled receptor kinase 2 (GRK2) interactome unveils new physiopathological targets

1 reference

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5 June 2018

Mitochondrial import of PKCepsilon is mediated by HSP90: a role in cardioprotection from ischaemia and reperfusion injury

1 reference

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G protein-coupled receptor kinase 2 (GRK2) modulation and cell cycle progression

1 reference

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5 June 2018

G-protein-coupled-receptor kinases mediate TNFα-induced NFκB signalling via direct interaction with and phosphorylation of IκBα.

1 reference

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5 June 2018

The basal flux of Akt in the mitochondria is mediated by heat shock protein 90.

1 reference

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5 June 2018

Differences in doxorubicin-induced apoptotic signaling in adult and immature cardiomyocytes

1 reference

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5 June 2018

Uncovering G protein-coupled receptor kinase-5 as a histone deacetylase kinase in the nucleus of cardiomyocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3908784

5 June 2018

Regulation of tumor cell mitochondrial homeostasis by an organelle-specific Hsp90 chaperone network.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3908784

5 June 2018

Physiological roles of G protein-coupled receptor kinases and arrestins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3908784

5 June 2018

Beta-arrestins and cell signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3908784

5 June 2018

Role of 90-kDa heat shock protein (Hsp 90) and protein degradation in regulating neuronal levels of G protein-coupled receptor kinase 3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3908784

5 June 2018

A crucial role for GRK2 in regulation of endothelial cell nitric oxide synthase function in portal hypertension.

1 reference

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5 June 2018

Activation of mu-opioid receptors transfers control of Galpha subunits to the regulator of G-protein signaling RGS9-2: role in receptor desensitization

1 reference

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5 June 2018

G protein-coupled receptor kinase 5 contains a DNA-binding nuclear localization sequence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3908784

5 June 2018

The pathophysiology of mitochondrial cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3908784

5 June 2018

New directions for protecting the heart against ischaemia-reperfusion injury: targeting the Reperfusion Injury Salvage Kinase (RISK)-pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3908784

5 June 2018

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3908784

5 June 2018

MAPK-dependent Degradation of G Protein-coupled Receptor Kinase 2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3908784

5 June 2018

Molecular chaperones Hsp90 and Hsp70 deliver preproteins to the mitochondrial import receptor Tom70

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3908784

5 June 2018

Mitochondrial PKCepsilon and MAPK form signaling modules in the murine heart: enhanced mitochondrial PKCepsilon-MAPK interactions and differential MAPK activation in PKCepsilon-induced cardioprotection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3908784

5 June 2018

Cytochrome c release from mitochondria proceeds by a two-step process

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3908784

5 June 2018

Seven-transmembrane-spanning receptors and heart function

1 reference

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5 June 2018

Clathrin box in G protein-coupled receptor kinase 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3908784

5 June 2018

Regulation of Pim-1 by Hsp90

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3908784

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Modulation of Akt kinase activity by binding to Hsp90

1 reference

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5 June 2018

Preservation of myocardial beta-adrenergic receptor signaling delays the development of heart failure after myocardial infarction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3908784

5 June 2018

Feedback inhibition of G protein-coupled receptor kinase 2 (GRK2) activity by extracellular signal-regulated kinases.

1 reference

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Agonist-dependent phosphorylation of the G protein-coupled receptor kinase 2 (GRK2) by Src tyrosine kinase

1 reference

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Hsp90's secrets unfold: new insights from structural and functional studies

1 reference

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The G protein-coupled receptor kinase 2 is a microtubule-associated protein kinase that phosphorylates tubulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3908784

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Protein kinase cross-talk: membrane targeting of the beta-adrenergic receptor kinase by protein kinase C.

1 reference

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Altered expression of beta-adrenergic receptor kinase and beta 1-adrenergic receptors in the failing human heart.

1 reference

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1 reference

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1 reference

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Akt mediates mitochondrial protection in cardiomyocytes through phosphorylation of mitochondrial hexokinase-II.

1 reference

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1 reference

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G Protein-coupled Receptor Kinase Interaction with Hsp90 Mediates Kinase Maturation

1 reference

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Myocyte redistribution of GRK2 and GRK5 in hypertensive, heart-failure-prone rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3908784

18 August 2018

Chelerythrine rapidly induces apoptosis through generation of reactive oxygen species in cardiac myocytes.

1 reference

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Binding and phosphorylation of tubulin by G protein-coupled receptor kinases

1 reference

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Morphological and molecular characterization of adult cardiomyocyte apoptosis during hypoxia and reoxygenation

1 reference

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Activation of beta-adrenergic receptor kinase during myocardial ischemia

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https://pubmed.ncbi.nlm.nih.gov/23467820

12 December 2020

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A Ubiquinone-binding Site Regulates the Mitochondrial Permeability Transition Pore

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1 reference

https://pubmed.ncbi.nlm.nih.gov/23467820

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Translocation of connexin 43 to the inner mitochondrial membrane of cardiomyocytes through the heat shock protein 90-dependent TOM pathway and its importance for cardioprotection

1 reference

https://pubmed.ncbi.nlm.nih.gov/23467820

12 December 2020

based on heuristic

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Identifiers

10.1161/CIRCRESAHA.112.300754

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

ResearchGate publication ID

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