(Q40753388)

23 September 2017

title

ERK activation mediates cell cycle arrest and apoptosis after DNA damage independently of p53. (English)

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23 September 2017

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Atsushi Hirao

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23 September 2017

Damu Tang

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23 September 2017

Dongcheng Wu

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23 September 2017

Jill M Lahti

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23 September 2017

Lieqi Liu

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23 September 2017

Brie Mazza

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23 September 2017

Vincent J Kidd

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23 September 2017

Tak W Mak

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23 September 2017

Alistair J Ingram

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23 September 2017

language of work or name

English

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publication date

30 January 2002

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Journal of Biological Chemistry

23 September 2017

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inferred from page(s)

published in

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23 September 2017

volume

277

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23 September 2017

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23 September 2017

page(s)

12710-12717

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p53 is required for radiation-induced apoptosis in mouse thymocytes

23 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

p53 sends nucleotides to repair DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

The DNA damage response: putting checkpoints in perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

Checkpoints: How to activate p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

Mdm2 promotes the rapid degradation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

Regulation of p53 stability by Mdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

Enhanced phosphorylation of p53 by ATM in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

DNA damage-induced activation of p53 by the checkpoint kinase Chk2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

JNK targets p53 ubiquitination and degradation in nonstressed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

p38 kinase mediates UV-induced phosphorylation of p53 protein at serine 389.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

The Drosophila gene hid is a direct molecular target of Ras-dependent survival signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

Making new connections: role of ERK/MAP kinase signaling in neuronal plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

Ras promotes cell survival in Drosophila by downregulating hid expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

Signal transduction. How receptors turn Ras on.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

The 3Rs of life: Ras, Raf and growth regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

Effect of extracellular signal-regulated kinase on p53 accumulation in response to cisplatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

Sustained activation of Ras/Raf/mitogen-activated protein kinase cascade by the tumor suppressor p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

ERKs and p38 kinase phosphorylate p53 protein at serine 15 in response to UV radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

Requirement for ERK activation in cisplatin-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

Caspase-8 activation and bid cleavage contribute to MCF7 cellular execution in a caspase-3-dependent manner during staurosporine-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

Akt is activated in response to an apoptotic signal.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

Cleavage of DFF-45/ICAD by multiple caspases is essential for its function during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

Etoposide (VP-16-213). Current status of an active anticancer drug

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

Involvement of the MKK6-p38gamma cascade in gamma-radiation-induced cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

Purification and characterization of ATM from human placenta. A manganese-dependent, wortmannin-sensitive serine/threonine protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

Raf-Induced Proliferation or Cell Cycle Arrest Is Determined by the Level of Raf Activity with Arrest Mediated by p21Cip1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

High-Intensity Raf Signal Causes Cell Cycle Arrest Mediated by p21Cip1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

Genetic instabilities in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

Lessons from hereditary colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

Radiation, DNA damage and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

p53, the cellular gatekeeper for growth and division

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

Participation of ATM in insulin signalling through phosphorylation of eIF-4E-binding protein 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

E1A signaling to p53 involves the p19(ARF) tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

Cycloheximide-induced T-cell death is mediated by a Fas-associated death domain-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111598200

21 January 2018

Identifiers

DOI

10.1074/JBC.M111598200

1 reference

23 September 2017

1 reference