(Q40627666)

22 September 2017

title

Caspase cleavage of the amyloid precursor protein modulates amyloid beta-protein toxicity (English)

1 reference

22 September 2017

Caspase cleavage of the amyloid precursor protein modulates amyloid β‐protein toxicity (English)

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02059.X

19 March 2024

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02059.X

19 March 2024

Salvador Soriano

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14535955

19 March 2024

Daniel C. Lu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14535955

19 March 2024

Dale E. Bredesen

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14535955

19 March 2024

Edward H. Koo

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14535955

19 March 2024

language of work or name

English

0 references

publication date

1 November 2003

1 reference

full work available at URL

22 September 2017

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1046%2Fj.1471-4159.2003.02059.x

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02059.X

https://onlinelibrary.wiley.com/doi/pdf/10.1046/j.1471-4159.2003.02059.x

19 March 2024

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02059.X

Journal of Neurochemistry

19 March 2024

published in

1 reference

22 September 2017

1 reference

22 September 2017

1 reference

22 September 2017

page(s)

733-741

1 reference

Amyloid beta-induced neuronal death is bax-dependent but caspase-independent.

22 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2003.02059.X

Activation of caspase-3 in single neurons and autophagic granules of granulovacuolar degeneration in Alzheimer's disease. Evidence for apoptotic cell death.

21 January 2018

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Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

21 January 2018

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The Bcl-2 protein family: arbiters of cell survival

15 July 2023

1 reference

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Multiple caspases are involved in beta-amyloid-induced neuronal apoptosis

19 March 2024

1 reference

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Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappaB and beta-amyloid precursor protein

19 March 2024

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Increased production of amyloid precursor protein provides a substrate for caspase-3 in dying motoneurons.

19 March 2024

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Amyloid beta peptide induces necrosis rather than apoptosis

19 March 2024

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A short cytoplasmic domain of the amyloid precursor protein induces apoptosis in vitro and in vivo.

19 March 2024

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Bcl‐2 Protects Isolated Plasma and Mitochondrial Membranes Against Lipid Peroxidation Induced by Hydrogen Peroxide and Amyloid β‐Peptide

19 March 2024

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A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

19 March 2024

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Apoptosis decision cascades and neuronal degeneration in Alzheimer's disease

19 March 2024

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Evidence of a novel event during neuronal death: development of competence-to-die in response to cytoplasmic cytochrome c

19 March 2024

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The caspase-derived C-terminal fragment of betaAPP induces caspase-independent toxicity and triggers selective increase of Abeta42 in mammalian cells

19 March 2024

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Aggregated Amyloid-β Protein Induces Cortical Neuronal Apoptosis and Concomitant “Apoptotic” Pattern of Gene Induction

19 March 2024

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Selective Phosphorylation of Adult Tau Isoforms in Mature Hippocampal Neurons Exposed to Fibrillar Aβ

19 March 2024

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02059.X

Caspase cleavage of members of the amyloid precursor family of proteins

19 March 2024

1 reference

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02059.X

Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation

19 March 2024

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Apoptotic cell death induced by beta-amyloid 1-42 peptide is cell type dependent

19 March 2024

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Activation of caspase-3 in beta-amyloid-induced apoptosis of cultured rat cortical neurons

19 March 2024

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beta-Amyloid protein-dependent nitric oxide production from microglial cells and neurotoxicity

19 March 2024

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Multiple pathways of apoptosis in PC12 cells. CrmA inhibits apoptosis induced by beta-amyloid

19 March 2024

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Neuronal apoptosis induced by beta-amyloid is mediated by caspase-8.

19 March 2024

1 reference

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Amyloid beta peptide induces cytochrome C release from isolated mitochondria

19 March 2024

1 reference

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The gamma secretase-generated carboxyl-terminal domain of the amyloid precursor protein induces apoptosis via Tip60 in H4 cells

19 March 2024

1 reference

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Caspase-6 role in apoptosis of human neurons, amyloidogenesis, and Alzheimer's disease

19 March 2024

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Apoptosis is induced by beta-amyloid in cultured central nervous system neurons

19 March 2024

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Amyloid beta interacts with the amyloid precursor protein: a potential toxic mechanism in Alzheimer's disease.

19 March 2024

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A second cytotoxic proteolytic peptide derived from amyloid beta-protein precursor

19 March 2024

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beta-Secretase cleavage of the amyloid precursor protein mediates neuronal apoptosis caused by familial Alzheimer's disease mutations

19 March 2024

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Fibrillar amyloid beta-protein mediates the pathologic accumulation of its secreted precursor in human cerebrovascular smooth muscle cells

19 March 2024

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Secreted form of amyloid beta/A4 protein precursor (APP) binds to two distinct APP binding sites on rat B103 neuron-like cells through two different domains, but only one site is involved in neuritotropic activity.

19 March 2024

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Caspase-9, Bcl-XL, and Apaf-1 form a ternary complex

19 March 2024

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Generation of an apoptotic intracellular peptide by gamma-secretase cleavage of Alzheimer's amyloid beta protein precursor.

19 March 2024

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Alternative, non-secretase processing of Alzheimer's beta-amyloid precursor protein during apoptosis by caspase-6 and -8.

19 March 2024

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Identification and transport of full-length amyloid precursor proteins in rat peripheral nervous system.

19 March 2024

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The amyloidogenic pathway of amyloid precursor protein (APP) is independent of its cleavage by caspases

19 March 2024

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Fas and Fas Ligand are associated with neuritic degeneration in the AD brain and participate in β-amyloid-induced neuronal death

19 March 2024

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Amyloid β-protein Induces Necrotic Cell Death Mediated by ICE Cascade in PC12 Cells

19 March 2024

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Caspase-2 mediates neuronal cell death induced by beta-amyloid

19 March 2024

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Proteolytic processing of the Alzheimer's disease amyloid precursor protein within its cytoplasmic domain by caspase-like proteases.

19 March 2024

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Toward understanding the molecular pathology of Huntington's disease.

19 March 2024

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Target protease specificity of the viral serpin CrmA. Analysis of five caspases

19 March 2024

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19 March 2024

Identifiers

1 reference

22 September 2017

1 reference