(Q40618783)

22 September 2017

title

P16INK4a is required for hSNF5 chromatin remodeler-induced cellular senescence in malignant rhabdoid tumor cells (English)

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22 September 2017

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Rob C Hoeben

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Igor Oruetxebarria

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22 September 2017

Francesca Venturini

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22 September 2017

Tuija Kekarainen

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22 September 2017

Ada Houweling

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22 September 2017

Lobke M P Zuijderduijn

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22 September 2017

Adone Mohd-Sarip

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22 September 2017

Robert G J Vries

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22 September 2017

C Peter Verrijzer

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22 September 2017

language of work or name

English

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publication date

6 November 2003

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Journal of Biological Chemistry

22 September 2017

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inferred from page(s)

published in

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22 September 2017

volume

279

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22 September 2017

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22 September 2017

page(s)

3807-3816

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The RB and p53 pathways in cancer

22 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309333200

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Immortalisation and transformation revisited

21 January 2018

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Tumor suppression by Ink4a-Arf: progress and puzzles

21 January 2018

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Chromatin silencing and activation by Polycomb and trithorax group proteins

21 January 2018

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Chromatin remodeling in development and differentiation.

21 January 2018

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SWI/SNF chromatin remodeling and cancer

21 January 2018

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Alteration of nucleosome structure as a mechanism of transcriptional regulation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M309333200

Mechanisms of chromatin assembly and transcription

21 January 2018

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Nuclear actin and actin-related proteins in chromatin remodeling.

21 January 2018

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ATP-dependent nucleosome remodeling

21 January 2018

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The chromatin remodelling factor Brg-1 interacts with beta-catenin to promote target gene activation

21 January 2018

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The C-terminal SET domains of ALL-1 and TRITHORAX interact with the INI1 and SNR1 proteins, components of the SWI/SNF complex

21 January 2018

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BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer

21 January 2018

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The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest

21 January 2018

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The Rb/E2F pathway: expanding roles and emerging paradigms

21 January 2018

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BRG-1 is required for RB-mediated cell cycle arrest

21 January 2018

1 reference

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RB and hbrm cooperate to repress the activation functions of E2F1

21 January 2018

1 reference

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Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer

21 January 2018

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Constitutional mutations of the hSNF5/INI1 gene predispose to a variety of cancers

21 January 2018

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Familial posterior fossa brain tumors of infancy secondary to germline mutation of the hSNF5 gene

21 January 2018

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Binding and stimulation of HIV-1 integrase by a human homolog of yeast transcription factor SNF5

21 January 2018

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Interaction of E1 and hSNF5 proteins stimulates replication of human papillomavirus DNA

21 January 2018

1 reference

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c-MYC interacts with INI1/hSNF5 and requires the SWI/SNF complex for transactivation function

21 January 2018

1 reference

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Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits

21 January 2018

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Essential roles of Snf5p in Snf-Swi chromatin remodeling in vivo

21 January 2018

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Disruption of Ini1 leads to peri-implantation lethality and tumorigenesis in mice

21 January 2018

1 reference

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The murine SNF5/INI1 chromatin remodeling factor is essential for embryonic development and tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309333200

Haploinsufficiency of Snf5 (integrase interactor 1) predisposes to malignant rhabdoid tumors in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309333200

A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309333200

Re-expression of hSNF5/INI1/BAF47 in pediatric tumor cells leads to G1 arrest associated with induction of p16ink4a and activation of RB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309333200

Cell cycle arrest and repression of cyclin D1 transcription by INI1/hSNF5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309333200

A key role of the hSNF5/INI1 tumour suppressor in the control of the G1-S transition of the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309333200

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M309333200

Germ line transmission of the Cdk4(R24C) mutation facilitates tumorigenesis and escape from cellular senescence

21 January 2018

1 reference

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Stabilization of p53 by p14ARF without relocation of MDM2 to the nucleolus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309333200

Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309333200

GAGA can mediate enhancer function in trans by linking two separate DNA molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309333200

Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309333200

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309333200

Use of chromatin immunoprecipitation to clone novel E2F target promoters

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M309333200

21 January 2018

The liberation of CD44.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309333200

Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309333200

INK4a-deficient human diploid fibroblasts are resistant to RAS-induced senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309333200

Biallelic mutations in p16(INK4a) confer resistance to Ras- and Ets-induced senescence in human diploid fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309333200

SNF2β-BRG1 is Essential for the Viability of F9 Murine Embryonal Carcinoma Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309333200

The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309333200

Genes involved in senescence and immortalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309333200

21 January 2018

Identifiers

DOI

10.1074/JBC.M309333200

1 reference

22 September 2017

1 reference