(Q34076841)

30 July 2017

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title

Genes involved in senescence and immortalization (English)

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30 July 2017

Lundberg AS

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30 July 2017

Hahn WC

series ordinal

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30 July 2017

Gupta P

series ordinal

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30 July 2017

Weinberg RA

series ordinal

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30 July 2017

publication date

1 December 2000

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Current Opinion in Cell Biology

30 July 2017

published in

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30 July 2017

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30 July 2017

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30 July 2017

page(s)

705-709

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Repression of c-fos transcription and an altered genetic program in senescent human fibroblasts

30 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900155-1

7 January 2021

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900155-1

7 January 2021

Senescence of human fibroblasts induced by oncogenic Raf.

1 reference

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7 January 2021

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900155-1

7 January 2021

E1A signaling to p53 involves the p19(ARF) tumor suppressor

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900155-1

7 January 2021

The serial cultivation of human diploid cell strains

1 reference

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7 January 2021

Mild Hyperoxia Shortens Telomeres and Inhibits Proliferation of Fibroblasts: A Model for Senescence?

1 reference

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7 January 2021

Oxidative DNA damage and senescence of human diploid fibroblast cells.

1 reference

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7 January 2021

Telomeres shorten during ageing of human fibroblasts

1 reference

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7 January 2021

Telomere length predicts replicative capacity of human fibroblasts

1 reference

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7 January 2021

Telomeres, telomerase and cancer

1 reference

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7 January 2021

A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon

1 reference

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7 January 2021

Telomeres, telomerase and senescence

1 reference

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7 January 2021

Telomerase, Cell Immortality, and Cancer

1 reference

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7 January 2021

Telomere reduction in human colorectal carcinoma and with ageing

1 reference

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7 January 2021

Extension of cell life-span and telomere length in animals cloned from senescent somatic cells

1 reference

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7 January 2021

Extension of life-span by introduction of telomerase into normal human cells

1 reference

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7 January 2021

Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span

1 reference

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7 January 2021

Restoration of telomeres in human papillomavirus-immortalized human anogenital epithelial cells

1 reference

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7 January 2021

Heterogeneity in telomere length of human chromosomes.

1 reference

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7 January 2021

Accumulation of short telomeres in human fibroblasts prior to replicative senescence

1 reference

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7 January 2021

Subsenescent telomere lengths in fibroblasts immortalized by limiting amounts of telomerase

1 reference

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7 January 2021

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

1 reference

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7 January 2021

Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900155-1

7 January 2021

The Effect of Low Oxygen Tension on the in Vitro-Replicative Life Span of Human Diploid Fibroblast Cells and Their Transformed Derivatives

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900155-1

7 January 2021

Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900155-1

7 January 2021

The free radical theory of aging matures

1 reference

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7 January 2021

The p66shc adaptor protein controls oxidative stress response and life span in mammals

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900155-1

7 January 2021

Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900155-1

7 January 2021

Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900155-1

7 January 2021

Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900155-1

7 January 2021

Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence

1 reference

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7 January 2021

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900155-1

1 reference

7 January 2021

p16INK4A and p19ARF act in overlapping pathways in cellular immortalization

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900155-1

7 January 2021

Inhibitors of cyclin-dependent kinases induce features of replicative senescence in early passage human diploid fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900155-1

7 January 2021

Features of replicative senescence induced by direct addition of antennapedia-p16INK4A fusion protein to human diploid fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900155-1

7 January 2021

p16 INK4a can initiate an autonomous senescence program

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900155-1

7 January 2021

Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900155-1

7 January 2021

Bypass of Senescence After Disruption of p21 CIP1/WAF1 Gene in Normal Diploid Human Fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900155-1

7 January 2021

Murine fibroblasts lacking p21 undergo senescence and are resistant to transformation by oncogenic Ras.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900155-1

7 January 2021

p19ARF links the tumour suppressor p53 to Ras

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900155-1

7 January 2021

p14ARF links the tumour suppressors RB and p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900155-1

7 January 2021

Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14(ARF) tumor suppressor

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900155-1

7 January 2021

Cooperative effects of INK4a and ras in melanoma susceptibility in vivo

1 reference

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7 January 2021

Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900155-1

7 January 2021

Defects in TGF-beta signaling overcome senescence of mouse keratinocytes expressing v-Ha-ras

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900155-1

7 January 2021

Atmospheric carbon dioxide concentrations over the past 60 million years

1 reference

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7 January 2021

Cellular response to oncogenic ras involves induction of the Cdk4 and Cdk6 inhibitor p15(INK4b)

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900155-1

7 January 2021

10.1016/S0955-0674(00)00155-1

Identifiers

DOI

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30 July 2017

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