(Q40591224)

21 September 2017

title

MDM2 mediates p300/CREB-binding protein-associated factor ubiquitination and degradation (English)

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21 September 2017

main subject

protein ubiquitination

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Yetao Jin

1 reference

21 September 2017

Shelya X Zeng

series ordinal

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21 September 2017

Hunjoo Lee

series ordinal

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21 September 2017

Hua Lu

series ordinal

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21 September 2017

language of work or name

English

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publication date

9 February 2004

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Journal of Biological Chemistry

21 September 2017

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inferred from page(s)

published in

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21 September 2017

volume

279

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21 September 2017

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21 September 2017

page(s)

20035-20043

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Regulation of p53 stability by Mdm2

21 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

Mdm2 promotes the rapid degradation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

Mdm2 association with p53 targets its ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

21 January 2018

The mdm2 Proto-Oncogene

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https://api.crossref.org/works/10.1074%2FJBC.M309916200

Amplification of a gene encoding a p53-associated protein in human sarcomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

Mdm2: keeping p53 under control

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

21 January 2018

p53: puzzle and paradigm

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https://api.crossref.org/works/10.1074%2FJBC.M309916200

p53, the cellular gatekeeper for growth and division

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

The complexity of p53 modulation: emerging patterns from divergent signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

A DNA damage-induced p53 serine 392 kinase complex contains CK2, hSpt16, and SSRP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

The p53-mdm2 autoregulatory feedback loop: a paradigm for the regulation of growth control by p53?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

The p53-mdm-2 autoregulatory feedback loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

MDM2 inhibits p300-mediated p53 acetylation and activation by forming a ternary complex with the two proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

p300/MDM2 complexes participate in MDM2-mediated p53 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

Interaction between the retinoblastoma protein and the oncoprotein MDM2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

Cyclin G recruits PP2A to dephosphorylate Mdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

MDM2 suppresses p73 function without promoting p73 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

MDM2 and MDMX bind and stabilize the p53-related protein p73

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

Mdm2 binds p73 alpha without targeting degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

The human MDM2 oncoprotein increases the transcriptional activity and the protein level of the p53 homolog p63.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

MDM2 promotes ubiquitination and degradation of MDMX

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

Estrogen receptor-dependent proteasomal degradation of the glucocorticoid receptor is coupled to an increase in mdm2 protein expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

Ligand-dependent interaction of the glucocorticoid receptor with p53 enhances their degradation by Hdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

Tip60 is targeted to proteasome-mediated degradation by Mdm2 and accumulates after UV irradiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

MDM2 inhibits PCAF (p300/CREB-binding protein-associated factor)-mediated p53 acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

Acetylation of general transcription factors by histone acetyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

Structure of histone acetyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

p53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

Mapping of the p53 and mdm-2 Interaction Domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

The N-terminal domain of p73 interacts with the CH1 domain of p300/CREB binding protein and mediates transcriptional activation and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

Histone-like TAFs within the PCAF histone acetylase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

Different effects of p14ARF on the levels of ubiquitinated p53 and Mdm2 in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

Polyubiquitination of p53 by a ubiquitin ligase activity of p300.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

MDM2 promotes p21waf1/cip1 proteasomal turnover independently of ubiquitylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

Ubiquitination regulates PSD-95 degradation and AMPA receptor surface expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

RETRACTED: Regulation of p53: intricate loops and delicate balances

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309916200

21 January 2018

Identifiers

DOI

10.1074/JBC.M309916200

1 reference

release_pryor33nbrblbny7gk3zbi6dkm

21 September 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/pryor33nbrblbny7gk3zbi6dkm

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference