(Q28609886)

3 February 2017

title

Mapping of the p53 and mdm-2 interaction domains (English)

1 reference

3 February 2017

Mapping of the p53 and mdm-2 Interaction Domains (English)

1 reference

https://api.crossref.org/works/10.1128/MCB.13.7.4107-4114.1993

18 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7686617

18 August 2024

J. Chen

1 reference

3 February 2017

V. Marechal

series ordinal

1 reference

3 February 2017

A. J. Levine

series ordinal

1 reference

3 February 2017

language of work or name

English

0 references

publication date

1 July 1993

1 reference

full work available at URL

3 February 2017

http://mcb.asm.org/cgi/content/abstract/13/7/4107

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7686617

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/7686617/pdf/?tool=EBI

18 August 2024

file format

Portable Document Format

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7686617

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/7686617/?tool=EBI

18 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7686617

https://europepmc.org/articles/PMC359960

18 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7686617

https://europepmc.org/articles/PMC359960?pdf=render

18 August 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7686617

https://journals.asm.org/doi/pdf/10.1128/mcb.13.7.4107-4114.1993

18 August 2024

1 reference

https://api.crossref.org/works/10.1128/MCB.13.7.4107-4114.1993

https://www.tandfonline.com/doi/pdf/10.1128/mcb.13.7.4107-4114.1993

18 August 2024

1 reference

https://api.crossref.org/works/10.1128/MCB.13.7.4107-4114.1993

Molecular and Cellular Biology

18 August 2024

published in

1 reference

3 February 2017

1 reference

3 February 2017

1 reference

3 February 2017

page(s)

4107–4114

1 reference

Molecular analysis and chromosomal mapping of amplified genes isolated from a transformed mouse 3T3 cell line

3 February 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

Mutations in the p53 gene occur in diverse human tumour types

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

Identification of p53 as a sequence-specific DNA-binding protein

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

p53 mutations in human cancers

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

Amplification of a gene encoding a p53-associated protein in human sarcomas

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

Oncogenic forms of p53 inhibit p53-regulated gene expression

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

DNA sequencing with chain-terminating inhibitors

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

Participation of p53 protein in the cellular response to DNA damage

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

T antigen is bound to a host protein in SY40-transformed cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

Monoclonal antibodies specific for simian virus 40 tumor antigens

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

Meth A fibrosarcoma cells express two transforming mutant p53 species

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

Two distinct regions of the murine p53 primary amino acid sequence are implicated in stable complex formation with simian virus 40 T antigen.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

Identification of the p53 protein domain involved in formation of the simian virus 40 large T-antigen-p53 protein complex

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

Wild-type p53 can inhibit oncogene-mediated focus formation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

The p53 proto-oncogene can act as a suppressor of transformation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

Nuclear accumulation of p53 protein is mediated by several nuclear localization signals and plays a role in tumorigenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

Structural aspects of the p53 protein in relation to gene evolution

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

The p53 tumour suppressor gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

A structural taxonomy of DNA-binding domains

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

Inhibition of p53 transactivation required for transformation by adenovirus early 1B protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

The transcriptional transactivation function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoprotein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

Site-specific binding of wild-type p53 to cellular DNA is inhibited by SV40 T antigen and mutant p53

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

Wild-type p53 is a cell cycle checkpoint determinant following irradiation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

p53: a transdominant regulator of transcription whose function is ablated by mutations occurring in human cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

Mutant p53 DNA clones from human colon carcinomas cooperate with ras in transforming primary rat cells: a comparison of the "hot spot" mutant phenotypes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

Association of human papillomavirus types 16 and 18 E6 proteins with p53.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

Domains required for in vitro association between the cellular p53 and the adenovirus 2 E1B 55K proteins.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

Cellular localization and cell cycle regulation by a temperature-sensitive p53 protein

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

Wild-type p53 mediates positive regulation of gene expression through a specific DNA sequence element

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

A C-terminal alpha-helix plus basic region motif is the major structural determinant of p53 tetramerization

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

Wild-type p53 activates transcription in vitro

3 June 2018

1 reference

12 December 2020

Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

1 reference

12 December 2020

MDM2 gene amplification in metastatic osteosarcoma

1 reference

12 December 2020

Adenovirus E1b-58kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54 kd cellular protein in transformed cells

1 reference

12 December 2020

Mutant p53 proteins bind DNA abnormally in vitro

1 reference

12 December 2020

Cotranslation of activated mutant p53 with wild type drives the wild-type p53 protein into the mutant conformation

1 reference

12 December 2020

6304

Kastan M. B.

1991

1 reference

https://api.crossref.org/works/10.1128/MCB.13.7.4107-4114.1993

18 August 2024

Ladanyi M.

1993

1 reference

https://api.crossref.org/works/10.1128/MCB.13.7.4107-4114.1993

The p53 protein and its interactions with the oncogene products of the small DNA tumor viruses

18 August 2024

1 reference

https://api.crossref.org/works/10.1128/MCB.13.7.4107-4114.1993

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

18 August 2024

1 reference

https://api.crossref.org/works/10.1128/MCB.13.7.4107-4114.1993

18 August 2024

Identifiers

10.1128/MCB.13.7.4107

1 reference

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=7686617

18 August 2024

1 reference

1 reference

1 reference