(Q40453661)

20 September 2017

title

Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis. (English)

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20 September 2017

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Eileen J McMahon

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20 September 2017

Samantha L Bailey

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20 September 2017

Carol Vanderlugt Castenada

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20 September 2017

Hanspeter Waldner

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20 September 2017

Stephen D Miller

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20 September 2017

language of work or name

English

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publication date

27 February 2005

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20 September 2017

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20 September 2017

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20 September 2017

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20 September 2017

page(s)

335-339

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Epitope spreading in immune-mediated diseases: implications for immunotherapy

20 September 2017

cites work

1 reference

Spontaneous regression of primary autoreactivity during chronic progression of experimental autoimmune encephalomyelitis and multiple sclerosis

21 January 2018

1 reference

Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen

21 January 2018

1 reference

Functional evidence for epitope spreading in the relapsing pathology of experimental autoimmune encephalomyelitis

21 January 2018

1 reference

A predictable sequential determinant spreading cascade invariably accompanies progression of experimental autoimmune encephalomyelitis: a basis for peptide-specific therapy after onset of clinical disease

21 January 2018

1 reference

Persistent infection with Theiler's virus leads to CNS autoimmunity via epitope spreading

21 January 2018

1 reference

Temporal development of autoreactive Th1 responses and endogenous presentation of self myelin epitopes by central nervous system-resident APCs in Theiler's virus-infected mice

21 January 2018

1 reference

Myelin-specific tolerance attenuates the progression of a virus-induced demyelinating disease: implications for the treatment of MS.

21 January 2018

1 reference

Immune response in draining lymph nodes and Spleen After Intraventricular Injection of Antigen

21 January 2018

1 reference

In situ processing and distribution of intracerebrally injected OVA in the CNS.

21 January 2018

1 reference

Initiation of immune responses in brain is promoted by local dendritic cells

21 January 2018

1 reference

Transfer of central nervous system autoantigens and presentation in secondary lymphoid organs

21 January 2018

1 reference

Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo

21 January 2018

1 reference

Microglia are activated to become competent antigen presenting and effector cells in the inflammatory environment of the Theiler's virus model of multiple sclerosis

21 January 2018

1 reference

Intracerebral recruitment and maturation of dendritic cells in the onset and progression of experimental autoimmune encephalomyelitis

21 January 2018

1 reference

Brain dendritic cells and macrophages/microglia in central nervous system inflammation

21 January 2018

1 reference

Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo.

21 January 2018

1 reference

Lymphatic efflux of intracerebrally injected cells

21 January 2018

1 reference

Lymphotoxin alpha/beta and tumor necrosis factor are required for stromal cell expression of homing chemokines in B and T cell areas of the spleen

21 January 2018

1 reference

Trafficking of superparamagnetic iron oxide particles (Combidex) from brain to lymph nodes in the rat.

21 January 2018

1 reference

Two subsets of dendritic cells are present in human cerebrospinal fluid

21 January 2018

1 reference

CD83-positive dendritic cells are present in occasional perivascular cuffs in multiple sclerosis lesions.

21 January 2018

1 reference

Expression of CCR7 in multiple sclerosis: implications for CNS immunity

21 January 2018

1 reference

Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis.

21 January 2018

1 reference

Fulminant spontaneous autoimmunity of the central nervous system in mice transgenic for the myelin proteolipid protein-specific T cell receptor

21 January 2018

1 reference

De novo central nervous system processing of myelin antigen is required for the initiation of experimental autoimmune encephalomyelitis.

21 January 2018

1 reference

Naive T lymphocytes traffic to inflamed central nervous system, but require antigen recognition for activation

21 January 2018

1 reference

Pathologic role and temporal appearance of newly emerging autoepitopes in relapsing experimental autoimmune encephalomyelitis

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Dendritic cells and differential usage of the MHC class II transactivator promoters in the central nervous system in experimental autoimmune encephalitis

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NM1202

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20 September 2017

1 reference