(Q28609886)

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Mapping of the p53 and mdm-2 Interaction Domains

scientific article published on July 1, 1993

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scholarly article

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PubMed publication ID

3 February 2017

Mapping of the p53 and mdm-2 interaction domains (English)

1 reference

PubMed publication ID

3 February 2017

Mapping of the p53 and mdm-2 Interaction Domains (English)

1 reference

10.1128/MCB.13.7.4107-4114.1993

https://api.crossref.org/works/10.1128/MCB.13.7.4107-4114.1993

18 August 2024

nuclear protein

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7686617

18 August 2024

author name string

J. Chen

1

1 reference

PubMed publication ID

3 February 2017

V. Marechal

2

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PubMed publication ID

3 February 2017

A. J. Levine

3

1 reference

PubMed publication ID

3 February 2017

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publication date

1 July 1993

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3 February 2017

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http://mcb.asm.org/cgi/content/abstract/13/7/4107

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7686617

18 August 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/7686617/pdf/?tool=EBI

Portable Document Format

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content deliverer

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7686617

18 August 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/7686617/?tool=EBI

online access status

content deliverer

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7686617

18 August 2024

https://europepmc.org/articles/PMC359960

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7686617

18 August 2024

https://europepmc.org/articles/PMC359960?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7686617

18 August 2024

https://journals.asm.org/doi/pdf/10.1128/mcb.13.7.4107-4114.1993

1 reference

10.1128/MCB.13.7.4107-4114.1993

https://api.crossref.org/works/10.1128/MCB.13.7.4107-4114.1993

18 August 2024

https://www.tandfonline.com/doi/pdf/10.1128/mcb.13.7.4107-4114.1993

1 reference

10.1128/MCB.13.7.4107-4114.1993

https://api.crossref.org/works/10.1128/MCB.13.7.4107-4114.1993

18 August 2024

Molecular and Cellular Biology

1 reference

PubMed publication ID

3 February 2017

13

1 reference

PubMed publication ID

3 February 2017

7

1 reference

PubMed publication ID

3 February 2017

4107–4114

1 reference

PubMed publication ID

3 February 2017

Molecular analysis and chromosomal mapping of amplified genes isolated from a transformed mouse 3T3 cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

17 March 2017

Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

17 March 2017

Mutations in the p53 gene occur in diverse human tumour types

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

17 March 2017

Identification of p53 as a sequence-specific DNA-binding protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

17 March 2017

p53 mutations in human cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

17 March 2017

Amplification of a gene encoding a p53-associated protein in human sarcomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

17 March 2017

Oncogenic forms of p53 inhibit p53-regulated gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

17 March 2017

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

17 March 2017

DNA sequencing with chain-terminating inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

17 March 2017

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

7 April 2017

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

7 April 2017

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

7 April 2017

Participation of p53 protein in the cellular response to DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

7 April 2017

T antigen is bound to a host protein in SY40-transformed cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

7 April 2017

Monoclonal antibodies specific for simian virus 40 tumor antigens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

29 September 2017

Meth A fibrosarcoma cells express two transforming mutant p53 species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

29 September 2017

Two distinct regions of the murine p53 primary amino acid sequence are implicated in stable complex formation with simian virus 40 T antigen.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

29 September 2017

Identification of the p53 protein domain involved in formation of the simian virus 40 large T-antigen-p53 protein complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

29 September 2017

Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

29 September 2017

Wild-type p53 can inhibit oncogene-mediated focus formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

29 September 2017

The p53 proto-oncogene can act as a suppressor of transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

29 September 2017

Nuclear accumulation of p53 protein is mediated by several nuclear localization signals and plays a role in tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

29 September 2017

Structural aspects of the p53 protein in relation to gene evolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

29 September 2017

The p53 tumour suppressor gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

29 September 2017

Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

29 September 2017

A structural taxonomy of DNA-binding domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

29 September 2017

Inhibition of p53 transactivation required for transformation by adenovirus early 1B protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

29 September 2017

The transcriptional transactivation function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

29 September 2017

Site-specific binding of wild-type p53 to cellular DNA is inhibited by SV40 T antigen and mutant p53

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

29 September 2017

Wild-type p53 is a cell cycle checkpoint determinant following irradiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

29 September 2017

p53: a transdominant regulator of transcription whose function is ablated by mutations occurring in human cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

29 September 2017

Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

29 September 2017

Mutant p53 DNA clones from human colon carcinomas cooperate with ras in transforming primary rat cells: a comparison of the "hot spot" mutant phenotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

3 June 2018

Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

3 June 2018

Association of human papillomavirus types 16 and 18 E6 proteins with p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

3 June 2018

Domains required for in vitro association between the cellular p53 and the adenovirus 2 E1B 55K proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

3 June 2018

Cellular localization and cell cycle regulation by a temperature-sensitive p53 protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

3 June 2018

Wild-type p53 mediates positive regulation of gene expression through a specific DNA sequence element

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

3 June 2018

Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

3 June 2018

A C-terminal alpha-helix plus basic region motif is the major structural determinant of p53 tetramerization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359960

3 June 2018

Wild-type p53 activates transcription in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/7686617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

1 reference

https://pubmed.ncbi.nlm.nih.gov/7686617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MDM2 gene amplification in metastatic osteosarcoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/7686617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenovirus E1b-58kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54 kd cellular protein in transformed cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7686617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant p53 proteins bind DNA abnormally in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/7686617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cotranslation of activated mutant p53 with wild type drives the wild-type p53 protein into the mutant conformation

1 reference

https://pubmed.ncbi.nlm.nih.gov/7686617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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