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Economic Impact of a New Rapid PCR Assay for Detecting Influenza Virus in an Emergency Department and Hospitalized Patients

Author

Listed:
  • Soto, Marcelo
  • Sampietro-Colom, Laura
  • Vilella, Anna
  • Marcos, María Ángeles
Abstract
Seasonal influenza causes significant morbidity and mortality and has a substantial economic impact on the healthcare system. The main objective of this study was to compare the cost per patient for a rapid commercial PCR assay (Xpert1 Flu) with an in-house real-time PCR test for detecting influenza virus. Community patients with influenza like-illness attending the Emergency Department (ED) as well as hospitalized patients in the Hospital Clínic of Barcelona were included. Costs were evaluated from the perspective of the hospital considering the use of resources directly related to influenza testing and treatment. For the purpose of this study, 366 and 691 patients were tested in 2013 and 2014, respectively. The Xpert1 Flu test reduced the mean waiting time for patients in the ED by 9.1 hours and decreased the mean isolation time of hospitalized patients by 23.7 hours. This was associated with a 103€ (or about $113) reduction in the cost per patient tested in the ED and 64€ ($70) per hospitalized patient. Sensitivity analyses showed that Xpert1 Flu is likely to be cost-saving in hospitals with different contexts and prices.

Suggested Citation

  • Soto, Marcelo & Sampietro-Colom, Laura & Vilella, Anna & Marcos, María Ángeles, 2016. "Economic Impact of a New Rapid PCR Assay for Detecting Influenza Virus in an Emergency Department and Hospitalized Patients," MPRA Paper 105581, University Library of Munich, Germany.
    • Handle: RePEc:pra:mprapa:105581
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    File URL: https://mpra.ub.uni-muenchen.de/105581/1/MPRA_paper_105581.pdf
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    References listed on IDEAS

    as
    1. Drummond, Michael F. & Sculpher, Mark J. & Torrance, George W. & O'Brien, Bernie J. & Stoddart, Greg L., 2005. "Methods for the Economic Evaluation of Health Care Programmes," OUP Catalogue, Oxford University Press, edition 3, number 9780198529453.
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    Cited by:

    1. Stephen Mac & Ryan O’Reilly & Neill K J Adhikari & Robert Fowler & Beate Sander, 2020. "Point-of-care diagnostic tests for influenza in the emergency department: A cost-effectiveness analysis in a high-risk population from a Canadian perspective," PLOS ONE, Public Library of Science, vol. 15(11), pages 1-15, November.

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    More about this item

    Keywords

    Influenza; PCR; Emergency Department; Proportional-hazard Regression; Survival data; Cost Minimization;
    All these keywords.

    JEL classification:

    • C5 - Mathematical and Quantitative Methods - - Econometric Modeling
    • I10 - Health, Education, and Welfare - - Health - - - General
    • I18 - Health, Education, and Welfare - - Health - - - Government Policy; Regulation; Public Health

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