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Behind the Scenes: Sources of Complementarity in R&D

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  • Marco Ceccagnoli
  • Matthew J. Higgins
  • Vincenzo Palermo
Abstract
Management consultants increasingly recommend that internal R&D be outsourced; however, little is known about the substitution or complementarity between internal and external R&D. Through structural estimation of a flexible innovation production function we provide a deeper understanding of firm‐level drivers of complementarity between these two types of investments. Our analysis is based on a unique panel data set on the R&D and in‐licensing expenditures of pharmaceutical firms. Our results suggest that internal R&D and in‐licensing are neither complements nor substitutes. We find that the degree of complementarity is enhanced for firms with stronger absorptive capacity, economies of scope, and licensing experience.

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  • Marco Ceccagnoli & Matthew J. Higgins & Vincenzo Palermo, 2014. "Behind the Scenes: Sources of Complementarity in R&D," Journal of Economics & Management Strategy, Wiley Blackwell, vol. 23(1), pages 125-148, March.
  • Handle: RePEc:bla:jemstr:v:23:y:2014:i:1:p:125-148
    DOI: 10.1111/jems.12048
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    1. Rebecca Henderson & Iain Cockburn, 1996. "Scale, Scope, and Spillovers: The Determinants of Research Productivity in Drug Discovery," RAND Journal of Economics, The RAND Corporation, vol. 27(1), pages 32-59, Spring.
    2. Ashish Arora & Alfonso Gambardella, 2010. "Ideas for rent: an overview of markets for technology," Industrial and Corporate Change, Oxford University Press and the Associazione ICC, vol. 19(3), pages 775-803, June.
    3. David J. TEECE, 2008. "Profiting from technological innovation: Implications for integration, collaboration, licensing and public policy," World Scientific Book Chapters, in: The Transfer And Licensing Of Know-How And Intellectual Property Understanding the Multinational Enterprise in the Modern World, chapter 5, pages 67-87, World Scientific Publishing Co. Pte. Ltd..
    4. Chris Forman & Avi Goldfarb & Shane Greenstein, 2008. "Understanding the Inputs into Innovation: Do Cities Substitute for Internal Firm Resources?," Journal of Economics & Management Strategy, Wiley Blackwell, vol. 17(2), pages 295-316, June.
    5. Tat Chan & Jack A. Nickerson & Hideo Owan, 2007. "Strategic Management of R& D Pipelines with Cospecialized Investments and Technology Markets," Management Science, INFORMS, vol. 53(4), pages 667-682, April.
    6. Grabowski, Henry, 2002. "Patents, Innovation and Access to New Pharmaceuticals," Working Papers 02-28, Duke University, Department of Economics.
    7. Tsai, Kuen-Hung & Wang, Jiann-Chyuan, 2008. "External technology acquisition and firm performance: A longitudinal study," Journal of Business Venturing, Elsevier, vol. 23(1), pages 91-112, January.
    8. Hall, Bronwyn H., 1993. "Industrial Research During the 1980s: Did the Rate of Return Fall?," Department of Economics, Working Paper Series qt33d879r9, Department of Economics, Institute for Business and Economic Research, UC Berkeley.
    9. Daron Acemoglu & Joshua Linn, 2004. "Market Size in Innovation: Theory and Evidence from the Pharmaceutical Industry," The Quarterly Journal of Economics, President and Fellows of Harvard College, vol. 119(3), pages 1049-1090.
    10. Patricia M. Danzon & Andrew Epstein & Sean Nicholson, 2007. "Mergers and acquisitions in the pharmaceutical and biotech industries," Managerial and Decision Economics, John Wiley & Sons, Ltd., vol. 28(4-5), pages 307-328.
    11. Bronwyn H. Hall, 1993. "Industrial Research during the 1980s: Did the Rate of Return Fall?," Brookings Papers on Economic Activity, Economic Studies Program, The Brookings Institution, vol. 24(2 Microec), pages 289-343.
    12. Henry Grabowski, 2002. "Patents, Innovation and Access to New Pharmaceuticals," Journal of International Economic Law, Oxford University Press, vol. 5(4), pages 849-860, December.
    13. Cohen, Wesley M & Levinthal, Daniel A, 1989. "Innovation and Learning: The Two Faces of R&D," Economic Journal, Royal Economic Society, vol. 99(397), pages 569-596, September.
    14. Arora, Ashish & Gambardella, Alfonso, 1994. "Evaluating technological information and utilizing it : Scientific knowledge, technological capability, and external linkages in biotechnology," Journal of Economic Behavior & Organization, Elsevier, vol. 24(1), pages 91-114, June.
    15. Berndt, Ernst R. & Christensen, Laurits R., 1973. "The translog function and the substitution of equipment, structures, and labor in U.S. manufacturing 1929-68," Journal of Econometrics, Elsevier, vol. 1(1), pages 81-113, March.
    16. Pollak, Robert A & Sickles, Robin C & Wales, Terence J, 1984. "The CES-Translog: Specification and Estimation of a New Cost Function," The Review of Economics and Statistics, MIT Press, vol. 66(4), pages 602-607, November.
    17. Andrea Fosfuri & Marco S. Giarratana & Alessandra Luzzi, 2008. "The Penguin Has Entered the Building: The Commercialization of Open Source Software Products," Organization Science, INFORMS, vol. 19(2), pages 292-305, April.
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    Cited by:

    1. Joshua L. Krieger & Xuelin Li & Richard T. Thakor, 2022. "Find and Replace: R&D Investment Following the Erosion of Existing Products," Management Science, INFORMS, vol. 68(9), pages 6552-6571, September.
    2. Spyros Arvanitis & Boris Lokshin & Pierre Mohnen & Martin Woerter, 2015. "Impact of External Knowledge Acquisition Strategies on Innovation: A Comparative Study Based on Dutch and Swiss Panel Data," Review of Industrial Organization, Springer;The Industrial Organization Society, vol. 46(4), pages 359-382, June.
    3. Ashish Arora & Michelle Gittelman & Sarah Kaplan & John Lynch & Will Mitchell & Nicolaj Siggelkow & Denisa Mindruta & Mahka Moeen & Rajshree Agarwal, 2016. "A two-sided matching approach for partner selection and assessing complementarities in partners' attributes in inter-firm alliances," Strategic Management Journal, Wiley Blackwell, vol. 37(1), pages 206-231, January.
    4. Graddy-Reed, Alexandra, 2020. "Getting ahead in the race for a cure: How nonprofits are financing biomedical R&D," Research Policy, Elsevier, vol. 49(8).
    5. Sitnicki Maksym, 2018. "Exploration of the role of business schools in the development of world-class research universities," Technology audit and production reserves, 1(39) 2018, Socionet;Technology audit and production reserves, vol. 1(5(39)), pages 36-45.
    6. Charles Hoffreumon & Chris Forman & Nicolas van Zeebroeck, 2024. "Make or buy your artificial intelligence? Complementarities in technology sourcing," Journal of Economics & Management Strategy, Wiley Blackwell, vol. 33(2), pages 452-479, March.
    7. Kwon, He-Boong & Lee, Jooh & Choi, Laee, 2022. "Dynamic interplay of operations and R&D capabilities in U.S. high-tech firms: Predictive impact analysis," International Journal of Production Economics, Elsevier, vol. 247(C).
    8. Billette de Villemeur, Etienne & Versaevel, Bruno, 2019. "One lab, two firms, many possibilities: On R&D outsourcing in the biopharmaceutical industry," Journal of Health Economics, Elsevier, vol. 65(C), pages 260-283.
    9. Maria Garcia-Vega & Oscar Vicente-Chirivella, 2019. "R&D and firm resilience during bad times," Discussion Papers 2019-13, University of Nottingham, GEP.
    10. María García-Vega & Óscar Vicente-Chirivella, 2020. "The effect of technology transfers from public research institutes and universities on firm innovativeness," Discussion Papers 2020-10, University of Nottingham, GEP.
    11. Keld Laursen & Solon Moreira & Toke Reichstein & Maria Isabella Leone, 2017. "Evading the Boomerang Effect: Using the Grant-Back Clause to Further Generative Appropriability from Technology Licensing Deals," Organization Science, INFORMS, vol. 28(3), pages 514-530, June.
    12. Li-Ying, Jason & Mothe, Caroline & Nguyen, Thi Thuc Uyen, 2018. "Linking forms of inbound open innovation to a driver-based typology of environmental innovation: Evidence from French manufacturing firms," Technological Forecasting and Social Change, Elsevier, vol. 135(C), pages 51-63.
    13. García-Vega, María & Vicente-Chirivella, Óscar, 2020. "Do university technology transfers increase firms’ innovation?," European Economic Review, Elsevier, vol. 123(C).
    14. Zhili Tian & Ralph Siebert, 2020. "Dynamic Effects of Licensing and Knowledge Transfer across Research Stages: Evidence from the Pharmaceutical Industry," CESifo Working Paper Series 8311, CESifo.
    15. Grimpe, Christoph & Sofka, Wolfgang & Schulz, Philipp & Borchhardt, Geoffrey Thilo, 2019. "Markets for technology in Europe: Mapping demand and its drivers," ZEW Discussion Papers 19-043, ZEW - Leibniz Centre for European Economic Research.
    16. Rehman, Naqeeb Ur, 2015. "Does Internal and External R&D Affect SMEs Innovation Performance? Micro Level Evidence from India and Pakistan," EconStor Preprints 113229, ZBW - Leibniz Information Centre for Economics.
    17. Mar�a Garc�a-Vega & Elena Huergo, 2019. "Asymmetric additionalities between R&D outsourcing locations," Discussion Papers 2019-08, University of Nottingham, GEP.
    18. Marshall S. Jiang & Jie Jiao & Zhouyu Lin & Jun Xia, 2021. "Learning through observation or through acquisition? Innovation performance as an outcome of internal and external knowledge combination," Asia Pacific Journal of Management, Springer, vol. 38(1), pages 35-63, March.
    19. García-Vega, María & Huergo, Elena, 2019. "The role of international and domestic R&D outsourcing for firm innovation," Journal of Economic Behavior & Organization, Elsevier, vol. 157(C), pages 775-792.
    20. María García‐Vega & Elena Huergo, 2021. "Organization of R&D outsourcing: Asymmetric cross‐effects between locations," Journal of Economics & Management Strategy, Wiley Blackwell, vol. 30(3), pages 503-524, August.
    21. Thomas Åstebro & Carlos J. Serrano, 2015. "Business Partners: Complementary Assets, Financing, and Invention Commercialization," Journal of Economics & Management Strategy, Wiley Blackwell, vol. 24(2), pages 228-252, June.
    22. Cabaleiro-Cerviño, Goretti & Burcharth, Ana, 2020. "Licensing agreements as signals of innovation: When do they impact market value?," Technovation, Elsevier, vol. 98(C).
    23. Koski, Heli & Svento, Rauli, 2014. "Knowledge Complementarity of a Firm’s Internal and External R&D Capabilities," ETLA Working Papers 25, The Research Institute of the Finnish Economy.
    24. Rehman, Naqeeb Ur, 2016. "Does Internal and External Research and Development Affect Innovation of Small and Medium-Sized Enterprises? Evidence from India and Pakistan," ADBI Working Papers 577, Asian Development Bank Institute.
    25. Un, C. Annique & Rodríguez, Alicia, 2018. "Learning from R&D outsourcing vs. learning by R&D outsourcing," Technovation, Elsevier, vol. 72, pages 24-33.

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    More about this item

    JEL classification:

    • L24 - Industrial Organization - - Firm Objectives, Organization, and Behavior - - - Contracting Out; Joint Ventures
    • L65 - Industrial Organization - - Industry Studies: Manufacturing - - - Chemicals; Rubber; Drugs; Biotechnology; Plastics
    • O31 - Economic Development, Innovation, Technological Change, and Growth - - Innovation; Research and Development; Technological Change; Intellectual Property Rights - - - Innovation and Invention: Processes and Incentives
    • O32 - Economic Development, Innovation, Technological Change, and Growth - - Innovation; Research and Development; Technological Change; Intellectual Property Rights - - - Management of Technological Innovation and R&D

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