[go: up one dir, main page]
IDEAS home Printed from https://ideas.repec.org/a/aph/ajpbhl/198979101385-1388_0.html
   My bibliography  Save this article

Delayed blood regeneration in lead exposure: An effect on reserve capacity

Author

Listed:
  • Grandjean, P.
  • Jensen, B.M.
  • Sando, S.H.
  • Jorgensen, P.J.
  • Antonsen, S.
Abstract
Twenty-five lead-exposed Danish battery production workers and 25-age-matched controls were examined to evaluate subclinical effects on blood formation. Blood lead levels averaged 2.14 μmol/L and 0.35 μmol/L in the two groups; the lead workers also showed high levels of erythrocyte protoporphyrin, as compared to the controls. Otherwise, the hematological parameters indicated an appropriate iron status and no other deviations. From all subjects, 0.45 L of blood was bled as part of a normal blood donation. Five and 11 days later, reticulocyte counts were significantly higher in the control group than in the lead-exposed workers. On day 15, the lead workers showed a significant delay in blood regeneration, as evidenced by lower hemoglobin concentration, and erythrocyte and reticulocyte counts. The lead exposure in the present study was within legal limits, and lead-induced anemia would be expected only at much higher exposure levels. Thus, despite the normal hematological findings in the initial examination, the lead exposure caused a decreased reserve capacity for blood formation, and this effect became evident only after the blood loss.

Suggested Citation

  • Grandjean, P. & Jensen, B.M. & Sando, S.H. & Jorgensen, P.J. & Antonsen, S., 1989. "Delayed blood regeneration in lead exposure: An effect on reserve capacity," American Journal of Public Health, American Public Health Association, vol. 79(10), pages 1385-1388.
    • Handle: RePEc:aph:ajpbhl:1989:79:10:1385-1388_0
    as

    Download full text from publisher

    To our knowledge, this item is not available for download. To find whether it is available, there are three options:
    1. Check below whether another version of this item is available online.
    2. Check on the provider's web page whether it is in fact available.
    3. Perform a search for a similarly titled item that would be available.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. von der Goltz, Jan & Barnwal, Prabhat, 2019. "Mines: The local wealth and health effects of mineral mining in developing countries," Journal of Development Economics, Elsevier, vol. 139(C), pages 1-16.
    2. Kanae Karita & Eiji Yano & Miwako Dakeishi & Toyoto Iwata & Katsuyuki Murata, 2005. "Benchmark Dose of Lead Inducing Anemia at the Workplace," Risk Analysis, John Wiley & Sons, vol. 25(4), pages 957-962, August.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:aph:ajpbhl:1989:79:10:1385-1388_0. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Christopher F Baum (email available below). General contact details of provider: https://www.apha.org .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.