[go: up one dir, main page]

IDEAS home Printed from https://ideas.repec.org/a/plo/pmed00/1002463.html
   My bibliography  Save this article

Treatment eligibility and retention in clinical HIV care: A regression discontinuity study in South Africa

Author

Listed:
  • Jacob Bor
  • Matthew P Fox
  • Sydney Rosen
  • Atheendar Venkataramani
  • Frank Tanser
  • Deenan Pillay
  • Till Bärnighausen
Abstract
Background: Loss to follow-up is high among HIV patients not yet receiving antiretroviral therapy (ART). Clinical trials have demonstrated the clinical efficacy of early ART; however, these trials may miss an important real-world consequence of providing ART at diagnosis: its impact on retention in care. Methods and findings: We examined the effect of immediate (versus deferred) ART on retention in care using a regression discontinuity design. The analysis included all patients (N = 11,306) entering clinical HIV care with a first CD4 count between 12 August 2011 and 31 December 2012 in a public-sector HIV care and treatment program in rural South Africa. Patients were assigned to immediate versus deferred ART eligibility, as determined by a CD4 count

Suggested Citation

  • Jacob Bor & Matthew P Fox & Sydney Rosen & Atheendar Venkataramani & Frank Tanser & Deenan Pillay & Till Bärnighausen, 2017. "Treatment eligibility and retention in clinical HIV care: A regression discontinuity study in South Africa," PLOS Medicine, Public Library of Science, vol. 14(11), pages 1-20, November.
  • Handle: RePEc:plo:pmed00:1002463
    DOI: 10.1371/journal.pmed.1002463
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1002463
    Download Restriction: no

    File URL: https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.1002463&type=printable
    Download Restriction: no

    File URL: https://libkey.io/10.1371/journal.pmed.1002463?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Matias D. Cattaneo & Luke Keele & Rocio Titiunik, 2023. "A Guide to Regression Discontinuity Designs in Medical Applications," Papers 2302.07413, arXiv.org, revised May 2023.
    2. Ahmed, Shahira & Autrey, Jessica & Katz, Ingrid T. & Fox, Matthew P. & Rosen, Sydney & Onoya, Dorina & Bärnighausen, Till & Mayer, Kenneth H. & Bor, Jacob, 2018. "Why do people living with HIV not initiate treatment? A systematic review of qualitative evidence from low- and middle-income countries," Social Science & Medicine, Elsevier, vol. 213(C), pages 72-84.
    3. Mhairi Maskew & Alana T Brennan & Matthew P Fox & Lungisile Vezi & Willem D F Venter & Peter Ehrenkranz & Sydney Rosen, 2020. "A clinical algorithm for same-day HIV treatment initiation in settings with high TB symptom prevalence in South Africa: The SLATE II individually randomized clinical trial," PLOS Medicine, Public Library of Science, vol. 17(8), pages 1-20, August.
    4. Jacob Bor & Anna Gage & Dorina Onoya & Mhairi Maskew & Yorghos Tripodis & Matthew P Fox & Adrian Puren & Sergio Carmona & Koleka Mlisana & William MacLeod, 2021. "Variation in HIV care and treatment outcomes by facility in South Africa, 2011–2015: A cohort study," PLOS Medicine, Public Library of Science, vol. 18(3), pages 1-18, March.
    5. Dean Eckles & Nikolaos Ignatiadis & Stefan Wager & Han Wu, 2020. "Noise-Induced Randomization in Regression Discontinuity Designs," Papers 2004.09458, arXiv.org, revised Nov 2023.
    6. Mariam O. Adeleke & Gianluca Baio & Aidan G. O'Keeffe, 2022. "Regression discontinuity designs for time‐to‐event outcomes: An approach using accelerated failure time models," Journal of the Royal Statistical Society Series A, Royal Statistical Society, vol. 185(3), pages 1216-1246, July.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pmed00:1002463. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosmedicine (email available below). General contact details of provider: https://journals.plos.org/plosmedicine/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.